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Yazar "Col Madendag, Ilknur" seçeneğine göre listele

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    A critical analysis of prophylaxis to avoid venous thromboembolism after cesarean delivery
    (2019) Eraslan Sahin, Mefkure; Col Madendag, Ilknur
    Aim: The aim of the present study was to analyze the risk factors for VTE in patients who underwent cesarean section. Pregnancy is a thrombogenic condition, and pregnant women have a five-to-six fold higher risk of VTE than non-pregnant women. The incidence of VTE is two-to-four times higher in cesarean deliveries than in vaginal deliveries.Material and Methods: 450 pregnant women who delivered by cesarean section were analyzed. The Turkey Ministry of Health Risk Pregnancy Management Guidelines was used to determine the VTE risk and its factors. After analyses of the data, the number and proportion of high-risk patients, that of medium-risk patients, and that of patients were determined.Results: After analyzing the risk factors we found that 59 (13.1%) pregnant women had a high risk, 351 (78%) had a moderate risk, and 40 (8.9%) had a low risk for VTE. In risk factor analyses, 9 women (2%) in the high-risk group had a history of VTE, 9 (2%) had a high risk of thrombophilia, 9(2%) had a low risk of thrombophilia and a family history of VTE, and 32(7.1%) needed low molecular–weight heparin during the antenatal period. When moderate-risk patients were classified for VTE, we found that 151 (33.6%) had two or more minor risk factors, 117 (26%) required cesarean section during labor, 42 (9.3%) had a hospital stay >3 days or were readmitted after delivery, 32 (7.1%) had a systemic disease, and 9 (2%) had a BMI>40 kg/m2. Conclusion: The results of the study suggest that the majority of pregnant women should be given VTE prophylaxis after cesarean delivery.
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    The effect of 17-alpha-hydroxyprogesterone caproate on 75 g oral glucose tolerance test results and the prevalence of gestational diabetes mellitus
    (2020) Col Madendag, Ilknur; Eraslan Sahin, Mefkure
    Aim: The goal of the present study was to investigate the effects of 17-alpha-hydroxyprogesterone caproate (17-OHPC) on oral glucose tolerance test (75 g OGTT) results and the prevalence of gestational diabetes mellitus (GDM). Material and Methods: : In the present case-control study, 1,472 pregnant women were enrolled. Of these pregnant women, 146 had used 17-OHPC for at least one month between 16–24 weeks of gestation and the remaining 1,326 were the healthy control group. Diagnostic criteria presented by International Association of Diabetes and Pregnancy Study Group were applied for diagnosis GDM.Results: Maternal demographic characteristics were similar between groups. The mean starvation serum glucose level was importantly greater in the study group at 81.7 ± 9.3mg/dL versus 79.6 ± 13.3mg/dL in the control group. Mean first hour serum glucose was 144.4 ± 30.4mg/dl in the study group and 130.8 ± 36.9mg/dl in the control group, importantly greater in the study group. Mean second hour serum glucose was importantly greater in the study group at 111.5 ± 26.1mg/dl versus 104.8 ± 31.4mg/dl in the control group. Additionally, there was no statistically significant difference between the groups for GDM prevalence.Conclusion: The present study showed that 17-OHPC was importantly related to greater starvation, first hour, and second hour serum glucose levels compared with the healthy group.
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    The effect of birth weight percentile on adverse neonatal morbidity in term uncomplicated pregnancies
    (2019) Eraslan Sahin, Mefkure; Col Madendag, Ilknur; Ak, Mehmet
    Aim: The goal of the present study was to evaluate the effect of birth weight percentile on adverse neonatal morbidity in term uncomplicated pregnancies.Material and Methods: This retrospective analysis comprised 7,817 pregnant women with uncomplicated pregnancies and single deliveries at term. The babies were divided into groups according to birth weight percentiles as follows: (1) Small for gestational age (SGA) (10 percentile), (2) 10–25 percentile, and 26–90 percentile. The primary outcome was adverse neonatal morbidity (ANM), defined as any of the following: Apgar score 4 at 5 min; respiratory distress; mechanical ventilation; intraventricular hemorrhage, grade III or IV; necrotizing enterocolitis, stage 2 or 3; neonatal sepsis, stillbirth or neonatal death.Results: Demographic and obstetric characteristics of the mothers were similar among the groups. ANM rates were 10.7% in the SGA group, 6.8% in the 10–25 percentile group, and 2.1% in the 26–90 percentile group, a significant difference. ANM was 5-fold higher in the SGA group and 3.2-fold higher in the 10–25 percentile group than in the 26–90 percentile group. Delivery induction or augmentation, cesarean delivery for non-reassuring fetal heart rate or fetal distress, Apgar score 4 at 5 min, mechanical ventilation, neonatal sepsis, stillbirth, or neonatal death significantly increased in the 10–25 percentile group compared with those in the 26–90 percentile group. Conclusion: The present study indicated that in uncomplicated pregnancies, fetuses with birth weights within the 10–25 percentile had a significantly increased risk of ANM compared to those within the 26–90 percentile.
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    Evaluation of exclusive breastfeeding rates and breastfeeding duration in term uncomplicated Turkish adolescent mothers
    (2020) Eraslan Sahin, Mefkure; Sahin, Erdem; Madendag, Yusuf; Col Madendag, Ilknur; Ak, Mehmet
    Aim: The aim of the present study was to evaluate exclusive breastfeeding (EBF) rates and breastfeeding duration in adolescent Turkish mothers after term-uncomplicated deliveries.Material and Methods: The study comprised 803 uncomplicated, nulliparous women, who had a single pregnancy and delivered at term gestational age. After excluding any maternal and fetal factors that affected early breastfeeding initiation, 674 nulliparous pregnant women were divided into three groups as follows: adolescents 16–17 years old, adolescents 18–19 years old, and non-adolescents 20–24 years old. The primary outcome of the study was defined as EBF of the infant, especially during the first 6 months of life. Results: Gestational age at delivery, birth weight, newborn gender, rate of induced labor, and rate of vaginal deliveries were similar among the groups. We found that 22.5% (14/62) of patients in the 16- to 17-year group, 41.8% (72/172) in 18- to 19-year group, and 72.9% (321/440) in the 20- to 24-year group had EBF during the first 6 months of their baby’s life. The rate of EBF during the first 6 months was significantly less in the 16- to 17-year and 18- to 19-year groups compared to that in the 20- to 24-year group (p0.001). The mean breastfeeding duration was 6.7±1.4months in the 16- to 17-year group, 9.5±2.2 months in the 18-to 19-year group, and 15.2±3.2 months in the 20-to 24-year group. Mean breastfeeding duration was significantly less in the 16-to 17-year and 18- to 19-year groups than in the 20- to 24-year group (p0.001).Conclusion: Our results indicated that adolescent pregnancy in Turkish populations is an important risk factor affecting both EBF during the first 6 months of life and breastfeeding duration.

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