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    Detection of intracavitary lesions in 436 infertile women by office hysteroscopy and comparison with histopathology results
    (2021) Colak, Eser; Zeyneloglu, Hulusi; Ozcimen, Emel Ebru; Eroglu, Semra
    Aim: To examine the importance of office hysteroscopy in detecting and treating endometrial pathologies of infertile patient groups.Materials and Methods: For this retrospective observational study, first, electronic hospital records were examined in order to identify patients who underwent office hysterescopy at our clinic, between 2003 and 2020, for infertility. The office hysteroscopy findings of 436 patients were included in the study, and examined and compared with the histopathological results.Results: The age distribution of the patients included in the study was homogeneous in terms of group variances. Thehysteroscopy findings of the patients were as follows: normal cavityin 137 patients(31.4%), endometrial polyps in 199 patients(45.6%), synechia in 14 patients(3.2%), subseptum or arcuate uterus in 32 patients (7.3%), t-shaped uterus in 28 patients (6.4%), cervical polyps in 6 patients (1.4%), Asherman’s syndrome in 6 patients (1.4%), and submucous myoma in 14 patients (3.2%). The most frequently detected lesion with office hysteroscopy was polyps,at a rate of 47% with 205 patients. In the pathology results, of the 137 patients who were diagnosed with normal endometrium via office hysteroscopy and underwent biopsy, 119were reported as normal (89.6%), while 6 were diagnosed with polyps (4.4%). The sensitivity and specificity of office hysteroscopy in detecting endometrial polyps were 94% and 56%, respectively.Conclusion: Office hysteroscopy may be one of the first alternative methods that can be used for safe and practical outpatient diagnosis and treatment in infertile patient groups.
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    Distribution of gynecological pathologies accompanying perimenopausal and postmenopausal adenomyosis
    (2021) Erinanc, Ozgur Hilal; Colak, Eser
    Aim: To determine the gynecological pathologies accompanying perimenopausal (PEM) and postmenopausal (PM) adenomyosis and to determine which of these pathologies may contribute to the etiology of adenomyosis. Materials and Methods: We retrospectively reviewed pathology report archives from between 2008 and 2018 and identified surgical hysterectomy specimens that were histopathologically diagnosed as cases of adenomyosis and the accompanying gynecological pathologies. Data regarding medical history were obtained from patient files. The patients were divided into two groups, PEM and PM, and they were compared. Results: There were a total of 212 patients (154 PEM and 58 PM) diagnosed with adenomyosis by histopathological examination of hysterectomy specimens. The most common complaints in the PEM patients were abnormal uterine bleeding and pelvic pain, and adenomyosis was frequently diagnosed incidentally in the PM women who underwent hysterectomy due to prolapse. The most common concomitant pathology among all patients was uterine leiomyomas, which affected 102 patients (48.1%), 80 of whom were in the PEM group and 22 in the PM group. The second most common accompanying pathology was endometrial polyps (22.2%, n =47), which was more common among the PM patients (PEM 16.9%, n = 26; PM 36.2%, n = 21). Endometriosis was more prominent in the PEM patients (12.3% n = 19), and 11.6% of the PEM patients had endometrial hyperplasia. Conclusion: Uterine leiomyoma was the most common gynecological pathology accompanying adenomyosis in both groups, and endometriosis and endometrial hyperplasia were significantly more common in the PEM group compared to the PM group. In line with our results, we think that common etiopathogenic factors may play a role in the pathogenesis of adenomyosis and the concomitant pathologies, and we have discussed our findings here in the light of the literature.