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    Genotype distribution in Hepatitis C patients admitted to Erzincan Mengücek Gazi Training and Research Hospital
    (2020) Yilmaz, Aysun; Kara, Murat; Karakecili, Faruk; Dabanlioglu, Bulent; Arslan, Yusuf Kemal
    Aim: We aimed to determine the genotype distribution in Hepatitis C patients who Parasitology applied to Erzincan Binali Yildirim University, Mengücek Gazi Training and Research Hospital. Hepatitis C virus, the only member of the genus Hepacivirus of Flaviviridae family, is responsible for 25%-40% of all liver diseases. Hepatitis C virus causes acute hepatitis C and chronic hepatitis C infections. Chronic hepatitis C infection causes cirrhosis, liver failure, hepatocellular cancerand liver diseases in terminal periods. Material and Methods: A total of 77 patients, 41 male and 36 female, who were admitted to Erzincan Binali Yıldırım University, Mengücek Gazi Training and Research Hospital in the period of January 2013-June 2019, were included in our study. RT-PCR and DNA sequencing for the 5’UTR region of the HCV genome for HCV genotyping was performed using the ABI Prism 3130 × 1 DNA Sequencer device.Results: Sex of a total of 77 patients included in the study; 41 of them are men (53.2%) and 36 are women (46.8%). Average age of the patients; It was 59.9 ± 16.6 (minimum 20 and maximum 94). HCV G1b (80.5%) in 62 patients, HCV G1a (7.8%) in 6, HCV G3a (3.9%) in 3, HCV G3 (2.6%) in 2 and HCV G2 (2.6%) was found in 2 patients. HCV G1 (1.3%) was detected in 1, HCV G4 (1.3%) in 1 patient.Conclusion: The dominant genotype in Hepatitis C patients who applied to Mengücek Gazi Training and Research Hospital was determined as “HCV Genotype 1b”.
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    Prevalence of cystic echinococcosis in humans in Erzincan Province
    (2020) Davarci, Ismail; Kara, Murat; Dabanlioglu, Bulent
    Aim: A study was carried out in human patients with suspicion of cystic echinococcosis. Echinococcosis granulosus is a zoonotic disease that causes cystic echinococcosis in humans and animals. The disease caused by adult or larval stages of tapeworms of the genus Echinococcus family.Material and Methods: 1,102 blood samples sent to Erzincan Binali Yıldırım University, Mengücek Gazi Training and Research Hospital Medical Microbiology Laboratory between January 2011 and December 2018 with suspicion of cystic echinococcosis were centrifuged at 1500 rpm for 10 minutes. Serum samples were tested immediately by indirect hemagglutination test in order to detect specific antibodies.Results: 248 of 1,102 blood samples of patients were found to be infected with cystic echinococcosis for the 9-year of period (an average annual incidence of 10.48 per 100,000 inhabitants). Conclusion: It is understood that hydatid disease is decreasing in the province, but there is always a risk of increases in cystic echinococcosis for humans.