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Öğe Blastic natural killer cell leukaemia with skin involvement: a case report(Wiley, 2004) Kaya, E; Ozcan, H; Kuku, I; Dikilitas, M; Sevinc, A; Aydogdu, INatural killer cell leukaemia is generally accompanied by extramedullary involvement. CD4+ natural killer cell leukaemia frequently manifests with cutaneous involvement. The disease pursues a very aggressive course with no long-term survivors reported. We present a patient with CD4+ natural killer cell leukaemia with skin, bone marrow and peripheral blood involvement who is still on remission at the end of 2 years.Öğe Cutaneous metastasis of endometrial carcinoma with hemorrhagic nodules and papules(Imr Press, 2005) Baydar, M; Dikilitas, M; Sevinc, A; Senel, S; Senel, F; Aydogdu, IBackground: Endometrium cancer is the fourth most frequent malignancy in women. However, skin metastasis from endometrium cancer is a very rare entity. Case: A 58-year-old multiparous woman postmenopausal for ten years presented with multiple metastatic, nodular, hemorrhagic skin lesions located at the initial surgery and radiotherapy site 14 months after the original diagnosis was made. Combination chemotherapy was instituted, but the patient died after the second cycle of chemotherapy. Conclusion: Although endometrial cancer is one of the most frequent malignancies in women, skin metastasis from endometrial cancer is very rare. In reported cases metastasis from endometrial cancer has been most commonly noted at the initial surgery and radiotherapy site. Therefore, the initial surgical and radiotherapy site must be examined carefully for skin metastasis.Öğe Hypopituitarism in older adults - The report of five cases with different presentations(Advanstar Communications, 2006) Cikim, A; Dikilitas, M; Cikim, KPatients with hypopituitarism may present with many different signs and symptoms which result from reduced secretion of one or more of pituitary hormones. Severe hyponatremia and hypoglycemia are rare but potentially life threatening presenting clinical features of hypopituitarism. As these abnormalities are completely restored with replacement therapy and patients are often undiagnosed until admission, a high clinical suspicion Is necessary to diagnose a patient 1 with hypopituitarism. We present five cases exhibiting rare symptoms of hypopituitarism-severe hyponatremia, hypoglycemia and osteoporosis-as the only presenting feature; these cases illustrate that hypopituitarism must be considered In the differential diagnosis of these abnormalities, especially in older patients.