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    A comparative study of superoxide dismutase, catalase, and glutathione peroxidase activities and nitrate levels in vitiligo patients
    (Wiley, 2005) Hazneci, E; Karabulut, AB; Öztürk, Ç; Batçioglu, K; Dogan, G; Karaca, S; Esrefoglu, M
    Background Several groups have shown the involvement of oxidative stress in the pathophysiology of vitiligo. Methods In this study, we examined the erythrocyte and plasma activities of glutathione peroxidase and Cu/Zn superoxide dismutase, plasma nitrite/nitrate levels, and erythrocyte catalase activity in 23 vitiligo patients and 25 controls. Results The results show that erythrocyte superoxide dismutase activity and plasma nitrite/nitrate levels are high in vitiligo patients. Conclusions Our study confirms that oxidative stress is involved in the pathophysiology of vitiligo, as indicated by the high levels of erythrocyte superoxide dismutase activity and plasma nitrite/nitrate.
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    Primary cutaneous anaplastic large cell lymphoma in a young girl
    (European Acad Dermatology & Venereology, 2001) Haznecl, E; Aydin, NE; Dogan, G; Turhan, IO
    [Abstract Not Available]
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    The risk of coronary heart disease in men with androgenetic alopecia
    (Elsevier Science Bv, 1999) Sasmaz, S; Senol, M; Ozcan, A; Dogan, G; Tuncer, C; Akyol, O; Sener, S
    Background The meaningful association of androgenetic alopecia and coronary heart disease has been well documented, but few studies have focused on the importance of lipid parameters, such as total cholesterol, triglycerides, high density lipoprotein-cholesterol, low density lipoprotein-cholesterol, lipoprotein (a), apolipoprotein A1 and apolipoprotein B in patients with androgenetic alopecia. Objective The aim of this study is to investigate the relation between androgenetic alopecia and coronary heart disease and to determine the significance of certain lipid parameters on this relationship. Subjects Forty-one men with vertex type androgenetic alopecia (study group) and 36 men, age-matched, with normal hair status (control group) were the subjects of this study. Results We found significant differences in serum lipoprotein (a) and triglyceride levels between the study and control groups (P < 0,05). Forty-seven percent of patients and 30% of controls had a lipoprotein (a) level more than 30 mg/dl higher than the level critical for atherosclerotic heart disease. Conclusion Dermatologists should investigate lipid profile, especially lipoprotein (a), of patients with androgenetic alopecia and refer to a cardiologist if necessary. (C) 1999 Elsevier Science B.V. All rights reserved.