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Öğe A 9-year follow-up of a girl with pyridoxine (vitamin B6)-dependent seizures: magnetic resonance spectroscopy findings(Verduci Publisher, 2012) Dogan, M.; Dogan, D. Gumus; Kahraman, A. S.; Ozcan, O.; Yakinci, C.; Alkan, A.Being an extremely rare condition makes the diagnosis of pyridoxine-dependent seizures (PDS) difficult. Early diagnosis of PDS is very important to prevent unwanted clinical outcomes. Elevated levels of glutamate and decreased levels of gamma-aminobutyric acid (GABA) in the frontal and parietal cortices are detected in this disorder. Here we present an 18 year old girl with PDS, who was reported 9 years ago with Magnetic Resonance Spectroscopy (MRS) findings. Present and past MRS findings showed a decrease in N-acetyl-aspartate-to creatine ratio on MRS. In this case it is surprising that neuronal damage has been preceded despite the administration of accurate treatment. That can be because of delay in treatment and/or under treatment.Öğe BILATERAL SPLIT FEET: A NEW FINDING IN CORNELIA DE LANGE SYNDROME(Medecine Et Hygiene, 2010) Dogan, D. G.; Dogan, M.; Aslan, M.; Karabiber, H.Bilateral split feet: a new finding in Cornelia de Lange Syndrome: We report on a male infant with Cornelia de Lange syndrome and bilateral split feet. Bilateral split feet do not appear to have ever been a reported feature in any of the published cases of Cornelia de Lange syndrome.Öğe Brain diffusion-weighted imaging in diabetic patients with retinopathy(Verduci Publisher, 2012) Dogan, M.; Ozsoy, E.; Doganay, S.; Burulday, V.; Firat, P. G.; Ozer, A.; Alkan, A.Objective: Our aim was to detect whether there is any change in apparent diffusion coefficients (ADC) levels in different sites of the brain, particularly in areas associated with the vision, in diabetic patients with retinopathy by measuring diffusion-weighted imaging (DWI). Materials and Methods: Conventional magnetic resonance imaging (MRI) and DWI of the brain were obtained from 45 diabetic patients (15 patients with proliferative diabetic retinopathy (group 1), 15 patients with nonproliferative diabetic retinopathy (group 2), 15 diabetic patients without retinopathy (group 3) and from 15 age-matched healthy volunteers (group 4). ADC values of visual cortex, cingulate gyrus, orbitofrontal, dorsomedial and dorsolateral frontal, corona radiate, and thalamus were obtained. Results: The ADC values of visual cortex, cingulate gyrus and orbitofrontal cortex significantly increased in groups 1 and 2 compared to groups 3 and 4 (p < 0.001). The ADC values of visual cortex significantly increased in group 1 compared to group 2 (p < 0.001). The duration of disease and value of HbA1c positively correlated with ADC values of the visual and orbitofrontal cortexes, and cingulate gyrus. Conclusions: We found an increase in ADC values supporting the neuronal loss in some regions, especially in visual center by DWI in the diabetic patients with retinopathy. This result supports the association between diabetic retinopathy and brain injury.Öğe CSF flow patterns in the brain in patients with neuro-Behcet disease and Behcet disease(Verduci Publisher, 2017) Unlu, S.; Dogan, M.; Kapicioglu, Y.; Kamisli, S.; Oner, S.; Yildirim, I. O.; Ozturk, M.OBJECTIVE: In the etiopathogenesis of Behcet disease (BD) and Neuro-Behcet disease (NBD), vascular eclipse occurs in both the arteries and veins. The disease affects all vascular structures. The present study evaluates the use of Phase Contrast (PC) Cerebral Spinal Fluid (CSF) Flow Magnetic Resonance Imaging (MRI), a non-invasive technique for measuring CSF dynamics, for determining the level of aqueducts that are influenced in BD and NBD. PATIENTS AND METHODS: The quantitative evaluation of CSF flow in BD and NBD was performed using images obtained at the level of the cerebral aqueduct on the semi-axial plane. The PC-MRI angiography technique was used. RESULTS: There is no distinctive difference between BD and NBD that can be distinguished by the aqueduct diameters of both conditions. A clear increase in aqueduct diameter occurred BD and NBD group when compared to the control group. While there were no differences found between the BD group and the control group regarding peak velocity, average velocity, forward flow, reverse flow, net forward flow, and flow, there were distinctive increases in these various factors in the NBD group. CONCLUSIONS: Using the non-invasive PC-MRI technique, this study found that in BD and NBD patients, changes occurred in CSF flow figures. Increases in CSF parameters were also observed in NBD patients, a finding which may be helpful for future distinction between BD and NBD during diagnosis.Öğe Diffuse edema and bilateral massive pleural effusion as the presentation of systemic lupus erythematosus(Sage Publications Ltd, 2011) Aslan, M.; Bicak, U.; Dogan, D. G.; Dogan, M.; Yakinci, C.A rare case of systemic lupus erythematosus (SLE), with massive bilateral pleural effusions and generalized edema as the first manifestations, is reported. The patient was a previously healthy 13-year-old boy. He presented with a history of fever, lack of appetite, gradually increasing fatigue, cough, diffuse edema, and moderate dyspnea. He responded well to corticosteroids with resolution of the pleural effusions, and edema. SLE should always be kept in mind in cases of massive pleural effusions and/or diffuse edema, even in the absence of other clinical manifestations of the disease. Lupus (2011) 20, 308-310.Öğe Effects of electromagnetic radiation produced by 3G mobile phones on rat brains: Magnetic resonance spectroscopy, biochemical, and histopathological evaluation(Sage Publications Ltd, 2012) Dogan, M.; Turtay, M. G.; Oguzturk, H.; Samdanci, E.; Turkoz, Y.; Tasdemir, S.; Alkan, A.Objective: The effects of electromagnetic radiation (EMR) produced by a third-generation (3G) mobile phone (MP) on rat brain tissues were investigated in terms of magnetic resonance spectroscopy (MRS), biochemistry, and histopathological evaluations. Methods: The rats were randomly assigned to two groups: Group I is composed of 3G-EMR-exposed rats (n = 9) and Group 2 is the control group (n = 9). The first group was subjected to EMR for 20 days. The control group was not exposed to EMR. Choline (Cho), creatinin (Cr), and N-acetylaspartate (NAA) levels were evaluated by MRS. Catalase (CAT) and glutathione peroxidase (GSH-Px) enzyme activities were measured by spectrophotometric method. Histopathological analyses were carried out to evaluate apoptosis in the brain tissues of both groups. Results: In MRS, NAA/Cr, Cho/Cr, and NAA/Cho ratios were not significantly different between Groups I and 2. Neither the oxidative stress parameters, CAT and GSH-Px, nor the number of apoptotic cells were significantly different between Groups I and 2. Conclusions: Usage of short-term 3G MP does not seem to have a harmful effect on rat brain tissue.Öğe Evaluation of Potential Donors in Living Donor Liver Transplantation(Elsevier Science Inc, 2015) Dirican, A.; Baskiran, A.; Dogan, M.; Ates, M.; Soyer, V.; Sarici, B.; Ozdemir, F.Introduction. Correct donor selection in living donor liver transplantation (LDLT) is essential not only to decrease the risks of complications for the donors but also to increase the survival of both the graft and the recipient. Knowing their most frequent reasons of donor elimination is so important for transplantation centers to gain time. In this study we evaluated the effectiveness of potential donors in LDLT and studied the reasons for nonmaturation of potential liver donors at our transplantation center. Patients and Methods. We studied the outcomes of 342 potential living donor candidates for 161 recipient candidates for liver transplantation between January 2013 and June 2014. Donor candidates' gender, age, body mass index (BMI), relationship with recipient, and causes of exclusion were recorded. Results. Among 161 recipients, 96 had a LDLT and 7 had cadaveric liver transplantation. Twelve of the 342 potential donors did not complete their evaluation; 106 of the remaining 330 donor candidates were accepted as suitable for donation (32%) but 10 of these were excluded preoperatively. The main reasons for unsuitability for liver donation were small remnant liver size (43%) and fatty changes of the liver (38.4%). Other reasons were arterial anatomic variations, ABO incompatibility, and Gilbert syndrome. Only 96 of the candidates (29% of the 330 candidates who completed the evaluation) underwent donation. Effective donors were 29% of potential and 90.5% of suitable donors. Conclusions. In our center, 106 of 330 (32%) donor candidates were suitable for donation and the main reasons for unsuitability for liver donation were small remnant liver size and fatty changes of the liver.Öğe Evaluation of Potential Donors in Living Donor Liver Transplantation (vol 47, pg 1315, 2015)(Elsevier Science Inc, 2015) Dirican, A.; Baskiran, A.; Dogan, M.; Ates, M.; Soyer, V.; Sarici, B.; Ozdemir, F.[Abstract Not Available]Öğe HANHART SYNDROME(Medecine Et Hygiene, 2010) Dogan, D. G.; Dogan, M.; Aslan, M.; Menekse, E.; Yakinci, C.Hanhart syndrome: We report on a male infant with Hanhart Syndrome. It is classified in oromandibular limb hypogenesis syndromes which are a group of rare conditions involving congenital malformations of tongue, mandible, and limbs.Öğe Incarcerated Morgagni hernia provoked by pregnancy(Sage Publications Ltd, 2010) Oguzturk, H.; Ates, M.; Turtay, M. G.; Dogan, M.; Ince, V.Morgagni hernias are rare diaphragmatic hernias, usually occurring on the right and located in the anterior mediastinum. Herniation of abdominal contents is typically caused by an increase in intraabdominal pressure secondary to trauma, pregnancy or obesity. In this article, a 35-year-old pregnant woman with a Morgagni hernia diagnosed on chest X-ray is presented. Emergency laparotomy was performed with reduction of the herniation and repair of the diaphragmatic defect. To our knowledge, this is the first reported case of hernia in a pregnant woman with incarcerated bowel presenting with respiratory and gastrointestinal symptoms from Turkey. (Hong Kong j.emerg.med. 2010;17:392-394)Öğe Intraosseous lipoma presenting as a sphenoid sinus mass(Verduci Publisher, 2011) Dogan, M.; Kahraman, A. S.; Firat, C.; Kahraman, B.; Karatas, E.; Kizilay, A.Intraosseous lipoma is an uncommon mesenchymal tumor that is frequently found in appendecular skeleton. In extremely rare conditions, it can appear in sphenoid bone, and only 2 cases have been described in literature until now. We present a case of lipoma in the body of the sphenoid bone mimicking sphenoid sinus tumor. A 16-year-old man presented to Department of Otorhinolaryngology with a complaint of nonspecific headache. There were any clinical findings on physical examination. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed and the diagnosis was made on these imaging findings. Other diagnostic technique, invasive histopathological assessment was not necessary. To our knowledge, this is the first case of lipoma in the body of the sphenoid bone with indentation to sphenoid sinus. The patient has been followed-up radiologically without the need for surgery for two years.Öğe Letter on the article "A rare tumour of the neck in a child"(ELSEVIER MASSON, VIA PALEOCAPA 7, 20121 MILANO, ITALY, 2017) Dogan, M.; Kahraman, A. S.; Yildirim, I. O.Öğe Letter on the article A rare tumour of the neck in a child(Elsevier Masson, 2017) Dogan, M.; Kahraman, A. S.; Yildirim, I. O.[Abstract Not Available]Öğe Multiple dural arteriovenous fistulas involving the cavernous sinus, transverse sinus, sigmoid sinus and spinal drainage: CT angiography findings in 14-year-old boy(Verduci Publisher, 2012) Dogan, M.; Kahraman, A. S.; Firat, C.; Ak, M.; Yildirim, O.; Dogan, D. G.Dural arteriovenous fistulas (DAVF) are rare and constitute 10% to 15% of all intracranial arteriovenous malformations. Only few cases of DAVFs are reported in children. Here is the first case report describing CT angiographic findings in a 14 year old child having multiple DAVFs involving spinal canal, both cavernous and cerebral sinuses.Öğe Primer malignant melanoma of kidney: a case report(Verduci Publisher, 2011) Tasdemir, C.; Samdanci, E. Turkmen; Dogan, M.; Elmali, C.; Sargin, S. YasarWe report a case of malignant melanoma of the kidney presenting as a primary tumor. This tumor was found incidentally in a 67-year-old man. This is a rare primer malign melanoma case of the kidney in 67-year old man, with no history of melanoma, presenting with an asymptomatic solitary renal mass. The patient underwent a right radical nephrectomy, We discuss the probability that this tumor is renal in origin and directly linked to the origin of malignant melanoma.Öğe A rare cause of ankle pain: concomitant intravenous lobular capillary haemangioma and arteriovenous fistula(Verduci Publisher, 2012) Turtay, M. G.; Samdanci, E.; Oguzturk, H.; Colak, C.; Dogan, M.Intravenous lobular capillary haemangioma (ILCH), also called intravenous pyogenic granuloma, is a rare benign lesion. These lesions are frequently showed themselves in the veins of the neck and upper extremities of young women. Clinical features are not specific. Ultrasonography can be used for diagnosis and showing additional pathologies such as arteriovenous fistula. The treatment is surgical excision. Correct pathologic diagnosis is required for differential diagnosis. We report an ILCH case presented to the Emergency Department with the complaints of pain and swelling in the ankle, originated from an arteriovenous fistula in vena saphena magna.Öğe Tramadol or paracetamol do not effect the diagnostic accuracy of acute abdominal pain with significant pain relief - a prospective, randomized, placebo controlled double blind study(Verduci Publisher, 2012) Oguzturk, H.; Ozgur, D.; Turtay, M. G.; Kayaalp, C.; Yilmaz, S.; Dogan, M.; Pamukcu, E.OBJECTIVES: To examine the effects of early administration of analgesics in patients with acute abdominal pain on pain severity, abdominal findings and diagnostic accuracy. METHODS: 210 patients with non-traumatic acute abdominal pain lasting less than 72 hours were enrolled to this trial. Patients were administrated by placebo, tramadol (1 mg/kg), or paracetamol (15 mg/kg) randomly after the first evaluation of pain severity scores (standard 100 mm visual analog scale) and abdominal findings (rebound, rigidity, tenderness). After 20 and 40 minutes of administrations, pain severity scores and abdominal findings were re-examined. Complete blood count, electrocardiography, plain abdominal x-ray, urine analysis and abdominal ultrasound were used for the initial diagnosis. The final diagnoses were decided after re-examinations, biochemical blood analysis, abdominal computed tomography in all patients and consultations or other diagnostic methods when necessary. RESULTS: There were 70 patients in each group. Baseline pain severity scores and abdominal findings were similar at all groups. After 20 minutes, pain severity scores were decreased in tramadol and paracetamol groups compared with the placebo group as 55% and 45% vs 1% respectively (p < 0.001). After 40 minutes, decreases on pain severity scores were more significant at treatment groups, 67% and 60% vs 0 (p < 0.001). When compared to placebo tramadol and paracetamol increased the new onset or worsening nausea or vomiting. There was no difference on abdominal findings among the groups after 20 and 40 minutes examinations. Diagnostic accuracy of tramadol, paracetamol and placebo groups were 96%, 94% and 94% respectively. CONCLUSIONS: Early administration of tramadol and paracetamol provided effective pain relief in patients with non-traumatic acute abdominal pain and those administrations did not interfere with diagnosis.
