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    Management of thrombosis in a pediatric renal transplant patient with factor vii deficiency a dilemma concerning recombinant factor VIIa
    (BETA Medical Publishers Ltd, 2020) Yalcin M.; Simsek A.; Tabel Y.; Dogan S.M.; Piskin T.
    Hemorrhagic complications in surgical patients with congenital factor VII deficiency are a major concern. Replacement therapy is required, in which recombinant factor VIIa is the first treatment choice, by virtue of its higher efficacy and no risk of infection. Because of the risk of vascular thrombosis, recombinant factor VIIa treatment may result in catastrophic outcomes, includ-ing graft loss in transplant patients. We present the case of a 7-year-old male who underwent renal transplantation and who developed renal thrombosis after recombinant factor VIIa substution therapy for factor VII deficiency. © 2020, BETA Medical Publishers Ltd. All rights reserved.
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    Subgaleal and epidural metastases of the undifferentiated embryonal sarcoma of the liver
    (Elsevier Inc., 2022) Dogan G.M.; Sığırcı A.; Okut G.; Dogan S.M.; Yilmaz S.
    Undifferentiated embryonal sarcoma of the liver (UESL) is very rare and has a very poor prognosis. UESL metastases have been reported in 5%-13% of the children with UESL and most metastases reported in the literature are present at diagnosis. Metastases reported in the literature belong to the lungs, pleura, and peritoneum. Radiological diagnosis of the UESL remains a poorly understood problem due to its rarity. Most of the reports published in the literature are also based on a relatively small number of patients. Approximately 200 cases have been reported regarding imaging features of this tumor. We reported a girl with UESL, who applied to the emergency department with abdominal pain. The lesion was solid and had cystic areas on ultrasound and there were peripherally enhanced serpenginous vessels in the lesion on Computed Tomography and MRI. Immunohistochemical diagnosis of the lesion was UESL. 26 months after surgery and adjuvant chemotherapy extradural and subcutaneus metastases were detected. These metastasis sites were first described for UESL. © 2021