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Öğe THE ALBUMIN-GLOBULIN RATIO PREDICTING MORTALITY IN GASTRIC CARCINOMA(Carbone Editore, 2016) Aksoy, Asude; Durak, Serdar; Ozturk, Turkan; Avci, Nilufer; Cirak, Yalcin; Deger, Ayse Nur; Bilgic, YilmazIntroduction: The potential effects of serum albumin and albumin-globulin rate on survival were investigated in patients with gastric carcinoma. Materials and methods: The biochemical values of 204 patients under chemotherapy evaluation were obtained retrospectively from archive data. Albumin-globulin ratio values were calculated using albumin/total protein-albumin formula. The values of albumin-globulin ratio and albumin were categorized as 3 groups using receiver operating characteristic analysis and a descending order. Results: The calculated cut-off value for albumin-globulin ratio was 1.14: 34.4-79.7 by receiver operating characteristic. The median survival was 20.7 months (15.9-25.5), 20.1 months (15.1-25.1), 16 months (11.8-20.1), respectively in 1st, 2nd, 3rd groups for albumin-globulin ratio (p=0.46). The median overall survival was 18.3 months (123-24.2), 21.6 months (16.8-26.3), 18.01 months (13.5-22.4) in 1st, 2nd, 3rd groups for albumin, respectively (p=0.52). There were no statistical significant differences by Kaplan-Meier method for albumin-globulin ratio, albumin p>0.05. The effects of clinicopathological and biochemical characteristics on mortality were assessed by Cox-proportional hazard regression analysis. The independent predictors of mortality were observed high grade, the presence of perineural invasion of the tumor, high nodal involvement (p:0.01, p:0.001, p:0.01), respectively. Conclusion: Albumin-globulin ratio and albumin values alone may not be useful parameters to predict mortality and survival in patients with gastric carcinoma.Öğe REAL LIFE EFFICACY AND TOLERABILITY OF TENOFOVIR ALAFENAMIDE FUMARATE IN PATIENTS WITH HEPATITIS B VIRUS-RELATED CIRRHOSIS AND LIVER TRANSPLANT RECIPIENTS. A-PRELIMINARY RESULT(Wiley, 2021) Yapali, Suna; Gokcan, Hale; Harputluoglu, Murat; Ellik, Zeynep Melekoglu; Akarsu, Mesut; Durak, Serdar; Gokcen, Pinar[Abstract Not Available]