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    The correlation between combined nasal and throat swab and chest CT findings in the diagnosis of COVID 19
    (2022) Torun, Mumtaz Taner; Durmaz, Dilber
    Aim: COVID-19 has spread rapidly, caused a pandemic and become a serious public health problem all over the world. The aim of the study is to investigate whether reverse transcriptase-polymerase chain reaction (RT-PCR) method, the most commonly used method for the diagnosis of COVID-19, correlate with the chest CT findings. Material and Methods: The file records of the patients with COVID-19 and suspected COVID-19 were examined retrospectively between 11 March and 30 August 2020 after the approval of the local ethics committee. Patient files were divided into 2 groups. RT-PCR negative patients were in group 1 and RT-PCR positive patients were in group 2. Combined nose and throat swab (CNTS) was used for swab sampling. Results: Of the 492 patients included in the study, 277 were men and 215 were women, with an average age of 57.45 ± 19.83. While there were 81 (29.2%) patients with chest CT findings compatible with COVID-19 in the first group, there were 80 (37.2%) patients in the second group. While the number of patients whose chest CT findings were incompatible with COVID-19 was 196 (70.8%) in group 1, it was 135 (62.8%) in group 2. There was a poor agreement between chest CT and RT-PCR in diagnosing COVID-19 (p = 0.062). Conclusion: To diagnose the disease is the most important step in treatment management. Especially in patients with incompatible RT-RCR and chest CT, the diagnosis should be strengthened by evaluating the laboratory findings and clinical symptoms of the patient.
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    Investigating the Impact of Body Composition Analysis on Quality of Life and Anxiety-Depression in Adult Males with Chronic Obstructive Pulmonary Disease
    (Mdpi, 2025) Kurtoglu, Ahmet; Eken, Ozgur; Ciftci, Rukiye; Cicek, Ipek Balikci; Durmaz, Dilber; Deniz, Mine Argali; Aldhahi, Monira I.
    Background/Objectives: Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by systemic manifestations, including altered body composition, reduced quality of life, and psychological distress. Despite its significance, the relationship between body composition parameters and symptoms of fatigue, anxiety, and depression in patients with COPD remains underexplored. This study aimed to examine the association between detailed body composition metrics and quality of life, fatigue, and anxiety and depression symptoms in male patients with COPD compared to healthy controls. Methods: This cross-sectional study included 49 men with COPD and 51 age-matched healthy controls aged 50-80 years. Body composition was assessed using bioelectrical impedance analysis (BIA). Pulmonary function, dyspnea, activities of daily living, and psychological status were evaluated using spirometry, the Medical Research Council Dyspnea Scale, the London Chest Activity of Daily Living Scale (LCADL), and the Hospital Anxiety and Depression Scale (HADS), respectively. Results: Compared to the controls, patients with COPD exhibited significantly lower forced expiratory volume in one second (FEV1: 1.1 vs. 2.16 L; p < 0.001), lower fat mass (15.0 vs. 24.3 kg; p < 0.001), and higher muscle mass (53.8 vs. 42.0 kg; p < 0.001). They also reported significantly greater fatigue (Borg scale: 4 vs. 0; p < 0.001), higher anxiety (8 vs. 5; p = 0.006), and depression scores (11 vs. 5; p < 0.001), along with more pronounced limitations in their daily activities. Conclusions: COPD is associated with profound impairments in body composition, physical function, and mental health. Detailed body composition analysis using BIA provides valuable clinical insights and may aid in tailoring individualized interventions to improve quality of life and psychological outcomes in COPD management.
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    Investigation of Factors Affecting Shuttle Walking Performance at Increased Speed for Patients with Chronic Obstructive Pulmonary Disease
    (Mdpi, 2023) Ciftci, Rukiye; Kurtoglu, Ahmet; Eken, Ozgur; Durmaz, Dilber; Eler, Serdar; Eler, Nebahat; Aldhahi, Monira I.
    The aim of this study was to examine the factors affecting the shuttle walking test (SWT) in patients with chronic obstructive pulmonary disease (COPD). A total of 29 patients with COPD (the COPD group) and a healthy group (HG) of 34 women aged between 55 and 74 years were included in the study. After the pulmonary function profiles of the participants were assessed, and the SWT was performed. Walking distances, walking speeds, and SWT levels (SWT-L) were determined with the SWT. Before and after the SWT, the heart rate (HR), oxygen saturation level (SPO2), and Borg scale (perceived exertion (BSe) and dyspnea (BSd)) results were analyzed with a paired sample t-test. The dyspnea levels during activity of daily living were determined with the Medical Research Council (MRC) dyspnea scale, and the relationship between MRC dyspnea (MRCD) and walking distance, speed, and SWT-L was tested using multiple linear regression and Pearson correlation analysis. The walking distance, speed, and SWT-L were lower in the COPD group (p < 0.001) than in the HG. The HR values before and after the SWT changed significantly in the COPD group and the HG (p< 0.001), and the effect size was higher in the COPD group. Although the BSe and BSd results before and after the SWT in the COPD group increased significantly (p < 0.001), they did not change in the HG. There was a highly negative correlation between MRCD and walking distance, speed, and SWT-L in the COPD group (p = 0.002, p = 0.000, and p = 0.001, respectively), but no correlation was found in the HG. The results showed that the HR, perceived exertion, and dyspnea levels of women with COPD whose respiratory functions were lower than the HG were significantly affected on the SWT.