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Öğe Effect of amyloidosis and proteinuria on augmentation index in patients with familial mediterranean fever(2019) Gurbuz, Ahmet Seyfeddin; Ozturk, Semi; Uslu, Ali Uğur; Efe, Suleyman Cagan; Ahbab, Elbis; Kirma, Cevat; Kucuk, AdemAim: There is a common belief that creativity and artistic talent/creativity are related to psychopathology. Mood disorders are more prominent in studies about relations between creativity and psychopathology. Also patients may be more productive during mania and hypomania periods of bipolar mood disorder. Considering these data, the purpose of this study was to investigate whether there is a predisposition to bipolar disorder in people with artistic creativity. Materials and Methods: A total of 157 students were selected randomly from the Art department and 157 from different departments including Faculties of Law, Science and Literature and Education. Art students had proven their artistic competence by two stage examination. Groups were compared based on mood disorder questionnaire (MDQ) and bipolarity predisposition factors. SPSS 22.0 was used for statistical analyses. Chi-square analysis was used to compare case-control groups according to demographic characteristics.Results: There were no significant differences between the groups in terms of age, sex, education, smoking, marital status, family history of psychiatric disorder. The number of psychiatric admissions were higher in the students of art (p=0.026). Alcohol-substance use was higher among students of Art (p=0.001). The MDQ scale result was 50.3% positive for Art students and 26.8% positive for students from different departments. MDQ scale, the predisposition of bipolar disorder was found to be significantly higher in Art students.Conclusion: The high prevalence of bipolarity features with MDQ scale in art students supports the relationship between artistic talent / creativity and bipolar disorder.Öğe The predictive value of the shock index and modified shock index for the short-term mortality in patients with acute pulmonary embolism(2020) Cinar, Tufan; Oz, Ahmet; Efe, Suleyman Cagan; Altintas, Mehmet S; Ayca, Burak; Karabag, TurgutAim: The purpose of the study was to examine the relationship of shock index (SI) and modified shock index (MSI) with pulmonary embolism severity index (PESI) score in predicting short-term death in acute pulmonary embolism (APE) patients. Material and Methods: This retrospective analysis included 104 consecutive patients whose APE was confirmed using computerized tomographic pulmonary angiography. For each patient, the PESI score, the SI, and the MSI were calculated. The main endpoint of the study was short-term mortality.Results: Patients based on hemodynamic status or the PESI score upon admission were allocated into high risk and non-high risk groups. We noted that SI and MSI were significantly elevated in a high risk group (1.17 ± 0.17 vs. 0.77 ± 0.17 and 1.54 ± 0.29 vs. 1.05 ± 0.21, respectively, p 0.001). In a correlation analysis, we showed that SI and MSI were significantly correlated with the PESI score for short-term mortality (r = 0.491 and r = 0.504, respectively, p 0.001). An area under curve value of SI and MSI for short-term death were 0.66 (0.52-0.79 95% CI, p = 0.022) and 0.67 (0.53-0.80 95% CI, p = 0.026) respectively.Conclusion: The present study findings demonstrated that the SI and MSI may be applicable in predicting short-death in patients with APE.Öğe Usability of aortic knob width as novel clinical predictor for coronary artery disease severity before elective coronary angiography(2020) Efe, Suleyman Cagan; Oz, Ahmet; Yalcin, Gunisil; Karabag, TurgutAim: In this study, we aimed to investigate the relationship between AKW and the severity of CAD in patients with stable CAD. Stable coronary artery disease (CAD) patients coronary artery disease severity is determined invasive coronary angiography scoring systems as SYNTAX and Gensini scores. Therefore, there is a need for noninvasive and easy to apply methods for determining the severity of the disease in stable CAD. Aortic knob width (AKW) is a measurable radiographic structure from chest X-ray.Material and Methods: The study included 168 patients with stable CAD ranging from 18 to 70 years old after exclusions criteria applied 114 patients examined. Patients grouped according to coronary artery vessel diameter narrowing above and below 70%. Patients Baseline characteristics, physical examination, medical treatments and laboratory findings recorded. The severity of CAD was evaluated by SYNTAX and Gensini scores. AKW measurement was also evaluated. Results: The two groups were statistically similar with respect to demographic properties and laboratory findings. Prior medications were similar between the groups. Furthermore percentage of diabetes mellitus and CRP levels were significantly different between groups (48.4%, 22% p:0.004 , 6.3±12, 2.4±4 p:0.049 respectively). AKW was significantly higher in group 1 compared to group 2 (41.1±6.2, 37.3±5.2; p=0.007). AKWs were correlated with Gensini and SYNTAX scores (r=0.25;p=0.007 and r=0.26;p=0.006 respectively). In a ROC analysis, the area under the curve value of AKW for CAD was 0.648 (95% CI: 0.544-0.752, p 22 were; DM (Odds ratio [OR]: 6,088, 95% CI: 1.617-22.927; P= 0.008) , AKW (OR: 1.122, 95% CI: 1.024-1.229;P= 0.013).Conclusion: To demonstrate the severity and complexity of coronary artery disease in stable coronary artery disease, noninvasive and simply calculated AKW can be used instead of invasively calculated the calculated SYNTAX and Gensini scores.