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Öğe Clinical and radiographic features of odontogenic keratocysts and evaluation of recurrence rates after treatment: A retrospective study(2019) Ege, Bilal; Demirkol, Mehmet; Yalçın, Mustafa; Alan, HilalAbstract: Aim: In this retrospective study, it was aimed to evaluate the clinical and pathological features of cases diagnosed with OKC and therecurrence status after treatment options.Material and Methods: 41 patients who were treated with the diagnosis of OKC between December 2015-June 2018 and whose preandpost-treatment follow-up data could be reached were included in the study. As the variables examined, age and gender of thepatients, localization of cyst and radiographic features, histopathological findings, treatment methods and recurrence status wereinvestigated retrospectively.Results: Of 41 patients with a mean age of 36.68±17.89 (age range 13 to 78) years, 24 (58.5%) were males and 17 (41.5%) werefemales. It was determined that OKCs were observed most frequently in the third decades (21.9%) followed by the second andfourth decades (19.5%). The incidence of OKC was determined to be higher in the mandible (80.5%) than in the maxilla (19.5%).The recurrence was observed in 7 of 41 cases (17.1%) after the treatment. The recurrence was detected particularly in mandibularposterior and larger lesions. The fact that five of the seven recurrent cases were parakeratotic and likewise five cases were treatedwith enucleation was noteworthy.Conclusions: The treatment and prognosis of OKC should be determined according to the condition of the case and the treatmentprotocol should be managed accordingly.Öğe Comparison of the Anesthetic Efficiency of Lidocaine and Tramadol Hydrochloride in Orthodontic Extractions: A Split-Mouth, Prospective, Randomized, Double-Blind Study(W B Saunders Co-Elsevier Inc, 2020) Ege, Bilal; Ege, Miray; Koparal, Mahmut; Alan, HilalPurpose: The aim of the present randomized controlled split-mouth clinical study was to evaluate and compare the clinical anesthetic efficacy of lidocaine and tramadol hydrochloride in orthodontic extractions. Materials and Methods: A total of 32 systemically healthy patients requiring bilaterally maxillary first premolar extractions for orthodontic reasons were included. Each patient received 1.8 mL of lidocaine (36 mg lidocaine HCI and 0.0225 mg epinephrine) on 1 side and 1.8 mL tramadol (50 mg tramadol HCl and 0.0225 mg epinephrine diluted to 1.8 mL by distilled water) on the other side. The anesthetic solutions were infiltrated into the buccal vestibule (local infiltration) based on a computer-generated list. In each patient, the time of anesthetic onset and finish, anesthetic activity, duration of postoperative analgesia, additional analgesic medication, wound healing, possible side effects, and satisfaction levels were recorded intraoperatively and postoperatively for both sides. Results: Although no relevant differences were found between the solutions for anesthetic onset, lidocaine was significantly more effective statistically for the total anesthesia duration. Comparing the anesthetic activity at 5 minutes before extraction, we found that tramadol was significantly more effective statistically compared with lidocaine. Similarly, tramadol was significantly more effective statistically than lidocaine for satisfaction level and wound healing. Moreover, compared with tramadol, in terms of postoperative pain, the visual analog scale scores with lidocaine were significantly higher at statistically 7, 8, 9, and 10 hours during the first 12 hours. In general, the lidocaine values were dramatically higher than were the tramadol values. Conclusions: The results of the present study suggest that using tramadol combined with epinephrine can be an alternative local anesthetic for maxillary first premolar tooth extractions in oral-maxillofacial surgery. (C) 2019 American Association of Oral and Maxillofacial SurgeonsÖğe Dentist visits of Syrian refugees and the cost of their dental healthcare(2019) Koparal, Mahmut; Ege, Bilal; Keskinruzgar, Aydin; Yapici Yavuz, Gunay; Erdogmus, Zozan; Unsal, Mustafa NafizAim: To investigate dental problems of Syrian refugees in southeast Turkey and assess the burden of their dental healthcare costs to government. Material and Methods: A retrospective study included dental records of Syrian refugees who applied to Adıyaman Dental Hospital (ADH), were compared with Adıyaman public by years.Results: In 2012, the most common treatments were tooth extraction and complicated tooth extraction, the total dental care cost of such refugee patients was $3,082.14 and the median cost per refugee was $4.43. The most common treatment provided to both the Adıyaman public and Syrian refugees in 2017 was dental filling. In the same year, total dental care cost of refugees was $603,303.69, the median cost per refugee was $22.20. The total dental care cost of the Adıyaman public was $3,869,524.96, the median dental care cost in Adıyaman public was $17.95 for one person in 2017.Conclusions: Dental problems of Syrian refugees and the financial burden of their dental healthcare to the government significantly increased.Keywords: Refugee; dental care cost; Syrian; immigrant; treatment; budgetÖğe The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible(2017) Ege, Bilal; Aksungur, Zeynep; Erdemli, Mehmet Erman; Akgül, Hasan; Bağ, Harika Gözde Gözükara; Selamoğlu, ZelihaAim: The present study investigated the changes in the liver tissues of rats with experimentally fractured mandible following the use of Grape Extract (GSE) and Low Level Laser Therapy (LLLT) in healing the fracture in dentistry. Materials and Methods: 60 adult male Wistar Albino rats were randomly assigned to 5 main groups (Control, Fractured Mandible (FM), FM + GSE, FM + LLLT, FM + LLLT + GSE), and then these groups were divided into two groups of 7 and 21 days (n = 6). A vertical fracture line passing through the molar teeth was formed in the right mandibles of all subjects except for these in the control group, and the fracture was internally fixed with a four-hole microplate and four micro-screws. Malondialdehyde (MDA), reduced glutathione (GSH), superoxide dismutase (SOD), catalase (CAT) activities were analyzed to determine the changes caused by GSE and LLLT administration in rat liver tissues in fractured mandibles. Results: It was determined that MDA and SOD levels in FM group and GSH and CAT activity levels in FM + GSE group and MDA levels in FM + LLLT group and GSH and CAT levels in FM + GSE + LLLT group increased statistically significantly to the control group on days 7 and 21. Conclusion: Biochemical parameters were investigated on the 7th and the 21st days, and it was determined that the oxidative damage caused by mandibular defects could be eliminated substantially in the rat liver especially with the administration of grapeseed that has antioxidant capacity.Öğe The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible(2017) Erdemli, Mehmet Erman; Akgul, Hasan; Ege, Bilal; Aksungur, Zeynep; Gozukara Bag, Harika; Selamoglu, ZelihaAim: The present study investigated the changes in the liver tissues of rats with experimentally fractured mandible following the use of Grape Extract (GSE) and Low Level Laser Therapy (LLLT) in healing the fracture in dentistry. Materials and Methods: 60 adult male Wistar Albino rats were randomly assigned to 5 main groups (Control, Fractured Mandible (FM), FM + GSE, FM + LLLT, FM + LLLT + GSE), and then these groups were divided into two groups of 7 and 21 days (n = 6). A vertical fracture line passing through the molar teeth was formed in the right mandibles of all subjects except for these in the control group, and the fracture was internally fixed with a four-hole microplate and four micro-screws. Malondialdehyde (MDA), reduced glutathione (GSH), superoxide dismutase (SOD), catalase (CAT) activities were analyzed to determine the changes caused by GSE and LLLT administration in rat liver tissues in fractured mandibles. Results: It was determined that MDA and SOD levels in FM group and GSH and CAT activity levels in FM + GSE group and MDA levels in FM + LLLT group and GSH and CAT levels in FM + GSE + LLLT group increased statistically significantly to the control group on days 7 and 21. Conclusion: Biochemical parameters were investigated on the 7th and the 21st days, and it was determined that the oxidative damage caused by mandibular defects could be eliminated substantially in the rat liver especially with the administration of grapeseed that has antioxidant capacityÖğe The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible(2017) Erdemli, Mehmet Erman; Selamoğlu, Zeliha; Akgül, Hasan; Ege, Bilal; Bağ, Harika Gözde Gözükara; Aksungur, ZeynepAim: The present study investigated the changes in the liver tissues of rats with experimentally fractured mandible following the use of Grape Extract (GSE) and Low Level Laser Therapy (LLLT) in healing the fracture in dentistry.Materials and Methods: 60 adult male Wistar Albino rats were randomly assigned to 5 main groups (Control, Fractured Mandible (FM), FM + GSE, FM + LLLT, FM + LLLT + GSE), and then these groups were divided into two groups of 7 and 21 days (n = 6). A vertical fracture line passing through the molar teeth was formed in the right mandibles of all subjects except for these in the control group, and the fracture was internally fixed with a four-hole microplate and four micro-screws. Malondialdehyde (MDA), reduced glutathione (GSH), superoxide dismutase (SOD), catalase (CAT) activities were analyzed to determine the changes caused by GSE and LLLT administration in rat liver tissues in fractured mandibles.Results: It was determined that MDA and SOD levels in FM group and GSH and CAT activity levels in FM + GSE group and MDA levels in FM + LLLT group and GSH and CAT levels in FM + GSE + LLLT group increased statistically significantly to the control group on days 7 and21.Conclusion: Biochemical parameters were investigated on the 7th and the 21st days, and it was determined that the oxidative damagecaused by mandibular defects could be eliminated substantially in the rat liver especially with the administration of grapeseed that has antioxidant capacity.Öğe Güneydoğu Anadolu Bölgesi’nde yedi farklı dental anomalinin görülme sıklığı(Selcuk Dental Journal, 2018) Koparal, Mahmut; Ünsal, Haluk Yener; Alan, Hilal Türker; Yalçın, Mustafa; Ege, Bilal; Gülsün, BelginÖz: Amaç: Bu çalışmanın amacı, Güneydoğu Anadolu Bölgesinde yaşayan bireylerde yedi farklı dental anomalinin görülme sıklığının ve cinsiyetler arasındaki dental anomali görülme yatkınlıkların değerlendirilmesidir. Gereç ve Yöntemler: Çalışma Adıyaman Üniversitesi Dişhekimliği Fakültesi’ne ve Adıyaman Ağız ve Diş Sağlığı Merkezi’ne çeşitli nedenlerle müracat etmiş hastalardan rastgele seçilen 4256 hastaya ait panoramik radyografi görüntüleri üzerinde retrospektif olarak tasarlandı. Hastalara ait panoramik radyografi görüntüleri dental anomalilerin tespit edilmesi amacıyla 2 araştırmacı tarafından değerlendirildi. Çalışmada hastaların panoramik radyografi görüntüleri üzerinde tespit edilen, alt keser diş eksikliği, sürnümerer diş, ektopi, gömülü kalma, mikrodonti, taurodontism ve dilaserasyon olmak üzere 7 tip dental anomali cinsiyetler arası dağılımına göre istatistiksel olarak analiz edilmiştir Bulgular: En sık görülen anomali %4,2 oranıyla gömülü kalma olarak tespit edildi. Taurodontizm % 0,02 lik oranla en az görülen anomali olarak tespit edildi. Gömülü diş görülme sıklığı erkek bireylerde, kadınlara kıyasla istatistiksel olarak anlamlı derecede daha fazla bulunmuştur. Ektopik diş görülme oranı, erkeklerde kadınlara nazaran istatistiksel olarak anlamı derecede fazla bulunmuştur. Kadınlarda alt keser diş eksikliği görülme oranı, erkeklere göre istatistiksel olarak anlamlı derecede fazla bulunmuştur. Sonuç: Güneydoğu Anadolu Bölgesinde yaşayan bireylerde gömülü kalma, en sık rastlanılan anomali olarak karşımıza çıkmaktadır. Alt keser diş eksikliği kadınlarda daha fazla görülürken, gömülü diş ve ektopiye erkeklerde daha sık rastlanılmıştır. Bunun yanında, sürnümerer diş, dilaserasyon, taurodontizm ve mikrodonti gibi anomalilerin görülme sıklığı bakımından cinsiyetler arasında farklılık tespit edilmemiştir. Taurodontizm en az rastlanılan anomali olarak tespit edilmiştir.Öğe Histomorphometric analysis of the effects of grape seed extract (vitis vinifera) and low-level laser therapy (LLLT) on fracture healing(2020) Ege, Bilal; Aras, Mutan Hamdi; Akgul, Hasan; Kara, Muhammed Isa; Aydemir, Isil; Inan, Sevinc; Taysi, Seyithan; Altundag Kahraman, SevilAim: In this study, we aim to investigate the effects of supplementary Grape Seed Extract (GSE) and Low-Level Laser Therapy (LLLT) on fracture healing, oxidant and anti-oxidant system in experimental mandible fractures.Material and Methods: 48 Wistar Albino rats (adult male, n=48) were used in our study. For all the subjects, a vertical fracture line through molar teeth in right mandibles was created and internally fixed using a four-hole microplate and four micro screws. Firstly, these subjects were randomly divided into 4 main groups (Control, GSE, LLLT, GSE+LLLLT) of 12 animals each, and then these were individually separated into two sub-groups of 7th and 21st days. The number of groups (n=6) was 8 in total. GSE of 300 mg/kg/day were provided to the subjects before they were sacrificed. LLLT of 23 J/cm2 was administered to two different points along with the fracture line at intervals of 48 hours for 7 days in the 7th day sub-groups and for 14 days in the 21st day sub-groups. After the procedure, while biochemical values such as TAS, TOS and OSI are measured; histopathologically it was examined in terms of capillary number and width, inflammatory cell, fibroblast count, collagen fibers, osteoblast count, ossification and mature bone formations.Results: For biochemical analyses, there was statistically significant difference only in TAS values on either the 7th or 21st day for the groups. Histological analyses showed that mandibular fracture healing were significantly better in the GSE and GSE+LLLT groups compared to the control group. The group of only LLLT had limited recovery while the combination of GSE+LLLT was the best for ossification.Conclusions: It is concluded that GSE may be one of the potential methods to accelerate fracture healings in mandibular fractures common in oral and maxillofacial surgery clinic and thus help patients recover in shorter time, and however LLLT can have positive effects on the process of ossification and recovery only when combined with the extract, which may result in better outcomes in clinical use.Öğe Inferior alveolar nerve paresthesia due to radicular cyst: A case and review of literature(2019) Ege, Bilal; Koparal, Mahmut; Yapici Yavuz, Gunay; Keskinruzgar, Aydin; Geyik, Abdussamed; Aydin Turk, BilgeRadicular cysts are inflammatory jaw cysts that form in the apices of infected and necrotic pulp teeth. They are usually asymptomatic and tend to grow slowly. However, depending on the progressive size of the lesion and its relation to neighboring tissues, it may cause mobility, root resorption and displacement. In addition, a limited number of studies have been reported in which paresthesia occurs as a result of local pressure caused by periapical pathology and various mandibular intraosseous lesions on nerve tissue. In this study, treatment process of the paresthesia of inferior alveolar nerve caused by radicular cyst which is remained asymptomatic for a long time in the left posterior mandible is presented in a 33 year-old male patient and it is evaluated in the light of current literature.Öğe Investigation preoperative seroprevalence of hbsag, anti-hbs, anti-hcv, anti-hiv and vaccination level of patients undergoing dental surgical procedure under local anesthesia(2019) Ege, Bilal; Koparal, Mahmut; Ozcan Kucuk, AyseAim: Health care workers especially dentists are at risk due to the fact that they are in direct contact with the blood and body fluids. In the present study, it was aimed to determine the preoperative seropositivity of HBsAG, anti-HBs, anti-HCV, and anti-HIV in the patients undergoing dental surgical procedure under local anesthesia.Material and Methods: 1598 patients who were admitted to Department of Oral and Maxillofacial Surgery between 2017-2018 and underwent surgical intervention for various reasons were included. Demographic data and serum samples taken preoperatively from patients were retrospectively evaluated in terms of HBsAg, Anti-HBs, Anti-HCV and Anti-HIV seropositivity by using archive records. Furthermore, the vocational and educational status of the HBsAg (+) patients in addition their awareness about hepatitis were investigated.Results: Of the 1598 patients, 591 (37%) were males; 1007 (63%) were females. The total number of patients with HBV carriers was 73 (4.6%), the number of anti-HBs-positive patients was 828 (51.8%), and the number of anti-HCV-positive patients was 3 (0.19%). Anti-HIV positivity has been observed in none of the patients. When evaluated according to the age ranges, HBsAg was mostly detected positive in the age ranges of 21-30 and 30-40; when evaluated according to sex, HBsAg was detected higher in women.Conclusions: Knowing the prevalence of infectious diseases is highly important for both the prevention and early diagnosis of these diseases. Besides, knowing the seropositivity of these diseases before surgical interventions will facilitate for both oral and maxillofacial surgeons and other health care personnel to take necessary safety precautions against disease transmission. For this purpose, although it was observed in our study that the preoperative HBsAg, anti-HBs, anti-HCV and anti-HIV seroprevalence were not higher than those in the population were, all health care workers should be trained in occupational diseases, vaccinated and followed up at regular intervals.Keywords: HBsAg; Anti-HCV; Anti-HIV; local anesthesia; dental surgery; seroprevalance; vaccine.
