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Öğe Abdominal pain, nausea, vomiting, and ascites in a 14-year-old girl with systemic lupus erythematosus: Answers(Springer, 2019) Elmas, Ahmet Taner; Tabel, YilmazYilmaz; Selimoglu, Ayse; Kenc, Senay; Kutlu, Ramazan[Abstract Not Available]Öğe Abdominal pain, nausea, vomiting, and ascites in a 14-year-old girl with systemic lupus erythematosus: Questions(Springer, 2019) Elmas, Ahmet Taner; Tabel, Yilmaz; Selimoglu, Ayse; Kenc, Senay; Kutlu, Ramazan[Abstract Not Available]Öğe Acute Kidney Injury Associated with Rapid Treatment of Hemodiafiltration for Bismuth Intoxication: Update and Review of the Literature(2013) Elmas, Ahmet Taner; Tabel, YılmazAbstract: On altı yaşında kız hasta bulantı ve kusma yakınmaları ile acil servisimize başvurdu. Öyküsünden, gün önce intihar amaçlı 35 adet De-Nol tablet (10,5 gr kolloidal bizmut subsitrat) aldığı öğrenildi. Başvuru anındaki fizik muayene bulguları normal olarak değerlendirildi. Laboratuar tetkiklerinde; BUN 76 mg/dl, kreatinin 19.2 mg/dl ve serum bizmut düzeyi 395 pg/lt idi. Hastaya sıvı ve elektrolit tedavisi, hemodiyaliz tedavisi ve şelatör ajan olarak penisilamin tedavileri başlandı. Daha sonra, 72 saat süreyle sürekli venö--venöz hemodiyafiltrasyon tedavisi uygulandı. Üç günlük hemodiyafiltrasyon tedavisi sonunda BUN: 14 mg/dl ve serum kreatinin düzeyi 0.78 mg/dl'ye geriledi. Penisilamin tedavisinin 14. gününde serum bizmut düzeyi 32 ug/L'ye düştü. Bu vaka; kolloidal bizmut subsitrat intoksikasyonu sonucu gelişen akut böbrek hasarının tedavisinde hemodiyaliz yan etkileri gözlendiğinde hemodiyafiltrasyonun alternatif bir tedavi yöntemi olabileceğini göstermiştir.Öğe Clinical Features of Children With Henoch-Schonlein Purpura Risk Factors Associated With Renal Involvement(Iranian Soc Nephrolgy, 2012) Tabel, Yilmaz; Nano, Filiz Callak; Dogan, Derya Gumus; Elmas, Ahmet TanerIntroduction. This study aimed to evaluate renal involvement and factors affecting the prognosis in patients with Henoch-Schonlein purpura (HSP). Materials and Methods. The outcomes of 107 children diagnosed with HSP who had been followed up for at least 6 months were reviewed. Results. Renal involvement was observed in 26.1% of the patients. The mean age of the patients with renal involvement was 8.8 +/- 4.0 years as compared to 7.1 +/- 2.9 years in the patients without renal involvement (P = .02). The risk of renal involvement was found to be significantly higher in the patients who were 10 years old and over (P < .001). In the group with renal involvement, the frequency of scrotal involvement was significantly higher than that of the group without renal involvement (P = .02). The mean serum immunoglobulin A level of the patients with renal involvements was significantly higher (P = .04) and the mean serum complement C3 levels was significantly lower (P = .04) than those of the patients without renal involvement. None of the patients with renal involvement reached end-stage kidney failure. No significant relationship was observed between the development of renal involvement and early steroid treatment. Conclusions. This study proposes that in old children with HSP, elevated serum immunoglobulin A levels, decreased serum complement C3 levels, and scrotal involvement are associated with renal involvement. We failed to find any effect of steroid treatment on development of renal involvement.Öğe Clinicopathological Analysis of Our Ten-Year Pediatric Percutaneous Kidney Biopsies(Galenos Publ House, 2022) Selcuk, Senay Zirhli; Elmas, Ahmet Taner; Akpolat, Nusret; Tabel, YilmazIntroduction: Our aim in this study is to evaluate the data of native and transplant kidney biopsies in our tertiary pediatric nephrology center in terms of demographics and clinico-pathology, to determine biopsy indications and to evaluate the compatibility of indication and histopathological diagnosis. Materials and Methods: In our study, the files and biopsy results (a total of 134 biopsy results) of 126 pediatric patients aged 1-17 years who were followed up in our Pediatric Nephrology clinic and underwent percutaneous kidney biopsy between 2011 and 2021 were evaluated retrospectively. All patients' age, gender, biopsy adequacy, compliance with the indication and histopathological diagnosis, and follow-up status were recorded. Results: Of 126 patients who underwent kidney biopsy, 62 (49.2%) were male; 64 (50.8%) were girls; mean age was 9.5 +/- 4.1 years. The most common biopsy indication was nephrotic syndrome (32.5%). Immunoglobulin A nephropathy (IgAN) was the most common histopathological diagnosis (23%). The concordance between clinical preliminary diagnosis and histopathological diagnosis was as high as 82.6%. Conclusion: The high rate of compatibility between the histopathological diagnosis and our preliminary diagnoses should not question the necessity of pathological evaluation, and even all kinds of examinations should be used to reach the most accurate diagnosis with the contribution of genetic studies.Öğe Comparison of Urinary Tract Dilatation and Society of Fetal Urology systems in the detection of vesicourethral reflux and renal scar(Int Scientific Information Inc, 2021) Dogan, Gulec Mert; Sigirci, Ahmet; Cengiz, Aslinur; Tasolar, Sevgi Demiroz; Yildiz, Turan; Tabel, Yilmaz; Elmas, Ahmet TanerPurpose: The presence and degree of hydronephrosis is very important in the management of many diseases of the urinary tract. In this study, we aim to compare the sensitivity and specificity of 2 classification systems that are used for hydronephrosis grading in ultrasound, for reflux and scar detection. The classification systems were the Society of Fetal Urology (SFU) and Urinary Tract Dilatation (UTD). Material and methods: Ultrasounds and dimercaptosuccinic acid scintigraphies (DMSA) of all patients who underwent voiding cystourethrogram (VCUG) due to urinary tract infection were examined retrospectively. DMSA was accepted for scar detection and VCUG for reflux detection as reference methods. SFU classification was used for hydronephrosis in ultrasound reports, and UTD classification was made over the reports. Sensitivity, specificity, and positive and negative predictive values of UTD and SFU classification systems for reflux and scar detection were calculated, and these 2 systems were compared. Results: 103 (39%) of the patients were male and 162 (61%) were female. Pathologies were detected in 192 (35%) of 530 kidneys in ultrasound. In 110 (42%) of the children, reflux was detected in VCUG. Scars in DMSA were detected in only 16% (44) of 266 kidneys. Sensitivity, positive and negative predictive values of the UTD classification system were statistically significantly higher than the SFU system for scar and reflux detection (p < 0.01). Conclusions: If we use the UTD system in ultrasounds of patients with urinary tract infections, children reported as UTD 0 may not need VCUG, which reduces radiation exposure to children and the cost of the diagnostic interventions.Öğe Crush Syndrome of Children in Kahramanmaraş Earthquake: A Single Center Experience in Malatya(Aves, 2024) Selcuk, Senay Zirhli; Elmas, Ahmet Taner; Tabel, YilmazObjective: Natural disasters cause enormous environmental, economic, and human losses. Children are the most vulnerable group and face severe consequences. While the primary cause of post -traumatic death is direct injury, the secondary cause is crush syndrome (CS). In this study, we aimed to share our experience in the management of children with CS during disasters by evaluating the clinical and laboratory outcomes of a group of 26 paediatric patients. Materials and Methods: Age, weight, length of time under rubble, laboratory results, and characteristics of crush injuries were assessed in 26 paediatric patients admitted to the emergency department after the earthquake. Diagnostic criteria for CS were established and the need for dialysis, hyperbaric oxygen or amputation and its determinants were assessed. Results: Crush syndrome was observed in 10 of the 26 patients. Significant differences in creatinine, aspartate aminotransferase, alanine aminotransferase, creatine kinase, hematocrit, pH, HCO3, and myoglobin levels were observed between patients with and without CS. None of the individuals rescued from the rubble within the first 6 hours had symptoms associated with CS. These 10 patients who developed CS were rescued within the first 48 hours of the earthquake, while 2 siblings were rescued after 81 hours and did not develop CS. Conclusion: The fact that the children were rescued from the rubble after 81 hours without developing CS shows the importance of patience in rescue operations. In addition, the very cold weather conditions during this earthquake may have prevented the development of dehydration and acute kidney injury and reduced the possibility of CS.Öğe Determination of reference values for urinary neutrophil gelatinase-associated lipocalin in premature infants(Informa Healthcare, 2014) Elmas, Ahmet Taner; Tabel, Yilmaz; Ipek, SevcanBackground: The aim of this study is to determine the reference values of urinary neutrophil gelatinase-associated lipocalin (uNGAL) in healthy very preterm infants. Method: The study was performed on 30 preterm infants whose gestational ages (GA) were between 28 and 34 weeks. They were divided into three groups according to the GA as group 1: GA 28-29 weeks, group 2: 30-32 weeks and group 3: 33-34 weeks. Blood and urine samples were obtained on postnatal (PN) days 1 and 7. uNGAL was measured by ELISA. Results: There were 10 preterm infants for each group. The median values of uNGAL on PN Days 1 were 19.80 (8.6-25.7) ng/ml, 9.25 (1.42-30.3) ng/ml, and 7.95 (1.60-27.8) ng/ml in group 1, group 2 and group 3, respectively. Multivariate linear regression analysis showed that uNGAL values are not associated with GA, birth weight, and gender in preterm infants on PN Days 1 and 7. Conclusion: Our study indicated that normal values of uNGAL concentrations in healthy very preterm infants, and older children or adults are similar preterm infants.Öğe Effectiveness of game-based core exercise in children with non-neuropathic bladder dysfunction and comparison to biofeedback therapy(Wiley, 2023) Kilcik, Melek Havva; Ozdemir, Filiz; Elmas, Ahmet TanerObjectives This study was planned to evaluate the effectiveness of game-based core exercises in children diagnosed with non-neuropathic bladder dysfunction and compare this effectiveness to that of the biofeedback treatment method. Methods The study included 48 children, aged 6-13 years, who were diagnosed with non-neuropathic bladder dysfunction. The children satisfying the inclusion criteria were selected by drawing lots from the population with the method of nonprobability random sampling. The patients were divided into three groups: group I, game-based core stabilization exercise training; group II, biofeedback program; and group III, game-based core stabilization exercise training in addition to the biofeedback program. The Dysfunctional Voiding and Incontinence Symptom Scale (DVISS) scores and uroflowmetry values of the patients were evaluated before and after the treatment. Results The mean age of the participants was 8.81 +/- 2.08 years. There was a statistically significant difference between the pretreatment and post-treatment DVISS scores in all three groups (p < .05). However, no significant difference was found among the groups. There was no statistically significant difference in the uroflowmetry results of the patients in group I and II before and after the treatment. In group III, the time to maximum flow rate after treatment was significantly reduced, and the average flow rate was significantly increased. Conclusions According to the results of this study, the use of game-based exercises along with biofeedback treatment may reduce DVISS scores in children with non-neuropathic bladder dysfunction. A combination of the two methods may have positively affected the uroflowmetry results of the patients. We think that game-based exercises will contribute to the literature as a new treatment option in the treatment of non-neuropathic bladder dysfunction.Öğe Effects of total parenteral nutrition on renal function in preterm neonate(Turkish Pediatrics Assoc, 2012) Tabel, Yilmaz; Oncul, Mehmet; Akin, Ilke Mungan; Karabulut, Aysun Bay; Elmas, Ahmet TanerAim: The aim of this study was to establish serum sistatine C, urine beta(2) microglobulin, gluthatione-S -transferase pi and N-acetyle beta-D glucosaminidase levels in order to evaluate the effect of total parenteral nutrition on renal function in premature infants. In addition, we aimed to compare the renal functions between premature infants receiving total parenteral nutrition and control groups receiving enteral feeding. Material and Method: A hundred four premature infants with a gestational age between 28 and 34 weeks were included in the study. The parenteral nutrition group consisted of 50 infants (male/female; 23/27 and mean weight 1258 +/- 212.3 g) and the enteral nutrition group consisted of 54 infants (male/female; 20/34 and mean weight 1608 +/- 206.1 g). In the parenteral nutrition group; total parenteral group nutrition was initiated on the 3rd day in the enteral nutrition group, minimal enteral nutrition was started on a mean of 6.3 +/- 2.4 days and total enteral nutrition was started on a mean of 24.5 +/- 6.3 days. Breastmilk was given orally or by orogastric/nasogastric tube at first day of life in the enteral group. On the 3rd and 30th day Of life, blood samples of all patients were obtained for evaluating biochemical parameters and cystatin C and urine samples were obtained for evaluation of N-acetyl beta-D glucosaminidase, gluthatione-S-transferase pi, beta(2) microglobulin, sodium, creatinin levels, density and pH of the urine. The study was approved by the ethics commite (2008/16). Results: When we compared the patients who received total parenteral nutrition and enteral nutrition on the 3rd and 30th days, serum cystatin C, urinary beta(2) microglobulin, gluthatione-S-transferase pi and N-acetyl- beta-D glucosaminidase excretions were similar on the 3rd day however were significantly higher on the 30th day in samples of the patients receiving total parenteral nutrition (p<0.05 for each parameter on each day). Conclusions: This study shows that total parenteral nutrition in premature infants can have adverse effects on glomerular and tubular functions of the kidney which can be manifested at an early time with cystatin C, beta(2) microglobulin, gluthatione-S-transferase pi and N-acetyl beta-D glucosaminidase. (Turk Arch Ped 2012; 47: 247-52)Öğe Erken doğmuş yenidoğanlarda total parenteral beslenmenin böbrek işlevleri üzerine etkileri(2012) Tabel, Yılmaz; Öncül, Mehmet; Akın, İlke Mungan; Karabulut, Aysun Bay; Elmas, Ahmet TanerAmaç: Erken doğmuş yenidoğanlarda total parenteral beslenmenin böbrek işlevleri üzerine etkilerini değerlendirmek için; serumda sistatin C, idrarda ?2 mikroglobülin, glütatyon-S-transferaz ? ve N-asetil ?-D glükozaminidaz düzeylerini saptayarak, total parenteral beslenme alanlar ile enteral beslenen kontrol grubu hastaların böbrek işlevlerinin karşılaştırılması amaçlanmıştır. Gereç ve Yöntem: Bu çalışma; gestasyonel yaşları 28-34 hafta arasında olan 104 erken doğmuş hastada yapıldı. Total parenteral beslenen 50 (Erkek/Kız: 23/27 ve ortalama ağırlıkları 1258±212,3 g) ve enteral beslenen 54 (Erkek/Kız: 20/34 ve ortalama ağırlıkları 1608±206,1 g) erken doğan bebek bu çalışmaya alındı. Total parenteral beslenme alan grupta üçüncü günden sonra total parenteral beslenme başlanırken, minimal enteral beslenmeye ortalama 6,3±2,4 günlerde ve tam enteral beslenmeye ortalama 24,5±6,3 günlerde geçildi. Enteral yolla beslenen gruba ise birinci gün anne sütü orogastrik/nazogastrik sonda ile veya ağızdan başlandı. Tüm hastaların üçüncü ve 30. günlerdeki serumdaki sistatin C, glükoz, BUN, kreatinin, total protein, albümin, AST, ALT, ALP, sodyum, potasyum, kalsiyum, fosfor ve idrardaki; N-asetil-?-D glükozaminidaz, glütatyon S-transferaz ?, ?2-mikroglobülin, sodyum, kreatinin, yoğunluk, pH ölçümleri değerlendirildi. Çalışma için etik kurul onayı alındı (2008/16). Bulgular: Total parenteral beslenme alan hastalar ile enteral beslenen hastaların üçüncü gün değerleri arasında anlamlı fark yokken, 30. gündeki serum sistatin C, idrar ?2 mikroglobülin, glütatyon-S-transferaz ? ve N-asetil ?-D glükozaminidaz değerleri karşılaştırıldığında total parenteral beslenme grubunda enteral beslenenlere göre anlamlı olarak yüksek olduğu saptandı (p<0,05). Çıkarımlar: Bu çalışma; total parenteral beslenmenin böbrekte glomerüler ve tübüler işlevler üzerine olumsuz etkilerinin olabileceğini ve bunun sistatin C, idrar ?2 mikroglobülin, glütatyon-S-transferaz ? ve N-asetil ?-D glükozaminidaz ile erkenden saptanabileceğini göstermesi bakımından anlamlı olmakla beraber, daha geniş serilerde ve daha homojen hasta gruplarında yapılacak çalışmalarla desteklenmesi gerekmektedir.Öğe Evaluation of Genotypic and Phenotypic Characteristics of Children with Familial Mediterranean Fever in Eastern Turkey(2019) Kalem, Hülya; kayhan tetik, Burcu; Elmas, Ahmet Taner; Selçuk, Engin Burak; Tabel, YılmazAbstract: Objective: Familial Mediterranean fever (FMF) is a hereditary disease. It usually affects countries in the Mediterranean region and is common in Turks. This retrospective study was conducted to evaluate phenotype-genotype characteristics of children with FMF in Malatya district and surrounding areas in eastern Turkey. Materials and methods: A total of 427 patients who had been diagnosed with clinical FMF between 2006 and 2015 were included in the study. Results: Of the patients, 207 (48.5%) were female, and 220 (51.5%) were male. The mean age of diagnosis was 7.7±3.7 years, and the age of onset of complaints was 5.7±3.5 years. The delay of diagnosis was 1.9±1.8 years. The most common complaint was abdominal pain (95.1%). The most commonly detected mutant allele was M694V (26.9%) mutation. We detected heterozygous mutations in 203 (52%) patients, homozygous mutations in 71 (18%) patients, compound heterozygous mutations in 81 (22%) patients, and no mutation in 8% of the patients. The most common homozygous mutation was M694V (57.7%), the most common heterozygous mutation was E148Q (38.4%), and the most common compound heterozygous mutation was M694V/M680I (17.1%). Conclusion: In our study, we found that the frequency of mutations was similar to that of the whole population of Turkey, and the severity of the disease was lower.Öğe Evaluation of hypertension by ambulatory blood pressure monitoring in children with solitary kidney(Taylor & Francis Ltd, 2015) Tabel, Yilmaz; Aksoy, Ozlem; Elmas, Ahmet Taner; Celik, Serkan FazliIn this study, we aimed to investigate the blood pressure (13P) profile in children with a unilateral functioning solitary kidney (UFSK). A group of 49 patients between the ages of 5 and 18 years, and 30 healthy controls between the ages of 6 and 16 years were investigated. Gender, weight, height and body mass index (BMI) of patients and controls were recorded. BP profile was determined by ambulatory BP monitoring (ABPM.). We have observed a higher risk of hypertension compared with healthy children. Also, masked hypertension is more frequently in the patients group and white-coat hypertension was observed in the control group. The mean night-time systolic BP (SBP) load (p = 0.01) and 24-h diastolic BP (DBP) load (p = 0.008) of children with multicystic dysplastic kidney (MCDK) was significantly higher than the healthy group. The mean night-time SBP load (p = 0.001) of children with unilateral renal agenesis (URA) and 24-h DBP load (p - 0.003) of children with unilateral atrophic or hypoplastic kidney were significantly higher than healthy group. We showed that the children with a solitary kidney had increased risk of hypertension. ABPM reflects the BP profile more precisely than casual BP measurement and it can be used to evaluate white-coat and masked hypertension in children with a solitary kidney.Öğe Evaluation of Renal Functions in Preterm Infants With Respiratory Distress Syndrome(John Wiley & Sons Inc, 2014) Tabel, Yilmaz; Oncul, Mehmet; Elmas, Ahmet Taner; Gungor, SerdalBackground: The aim of this prospective study was to evaluate urinary glutathione S transferases p (GST-pi), beta-2-microglobulin (B2-MG), and N-acetyl-beta-D-glucosaminidase (NAG) levels as markers revealing the effect of respiratory distress syndrome (RDS) on renal function in preterm infants. Methods: The study was performed with 76 preterm infants whose gestational ages were between 28 and 32 weeks. Twenty-six preterm infants with RDS (cases) and 50 preterm infants without RDS (controls) enrolled in the study. Blood and urine samples were obtained on postnatal (PN) day 3 and 30. Urinary GSTp levels were measured by enzyme-linked immunosorbent assay (ELISA), and urinary B2-MG levels were determined by nephelometric method. Results: There was no significant difference in urinary B2-MG and GST-pi levels between RDS and non-RDS groups on PN day 3 (P > 0.05 for each). However, preterm infants with RDS had significantly higher urinary B2-MG and GSTp levels than the control group on PN day 30 (P = 0.0001 and P = 0.031, respectively). Urinary NAG levels were higher in RDS group than those of the controls on both PN day 3 and 30, but these findings were not statistically significant (P > 0.05, for each). Conclusion: Preterm infants with RDS had increased levels of both GST-p and B2-MG levels on PN day 30, suggesting subclinical tubular dysfunction, probably secondary to hypoxic stress. (C) 2014 Wiley Periodicals, Inc.Öğe Evaluation of renal tubular function in epileptic children treated with levetiracetam(2016) Elmas, Ahmet Taner; Güngör, Serdal; Arslan, Müjgan; Tabel, Yılmaz; Raif Güngör, Sabiha; Özyalın, FatmaAbstract: Our study aim was to measure the urinary N-acetyl-?-D-glucosaminidase/creatinine (NAG/UCr) index in epileptic children who received levetiracetam (LEV) treatment at least for 6 months, and compare it to healthy children. Thirty five children with epilepsy were enrolled in this prospective study. NAG was studied using the calorimetric method and NAG levels were expressed in units per liter (U/L) and NAG/UCre levels were determined in U/mmol creatinine. There were no statistically significant differences for the urine NAG and NAG/UCr index before and after LEV treatment in the epileptic group (p>0.05, for each). There were no significant correlations between the serum concentration of LEV and urinary NAG levels (r=0.258, p=0.135) and NAG/UCr levels (r=0.164, p=0.346) before treatment. Our study demonstrated that LEV treatment was safe and did not interfere in renal tubular function in epileptic childrenÖğe Fifteen Years of Experience in Ambulatory Blood Pressure Monitoring in Children at a Single Center(Erciyes Univ Sch Medicine, 2023) Sapcioglu, Mustafa; Selcuk, Senay Zirhli; Elmas, Ahmet Taner; Tabel, YilmazObjective: This study was conducted at a tertiary medical center in a region where similar studies had not been previously conducted. It aimed to analyze 15 years of data obtained from the ambulatory blood pressure monitoring (ABPM) program and to address the challenges associated with diagnosing hypertension (HT).Materials and Methods: This study included 1,859 children aged 5-18 years who were admitted between 2005 and 2020 and diagnosed with HT according to clinical measurements. All necessary demographic and clinical data were collected retrospectively. Measurements were performed using the Mobil-O-Graph device. Results: A total of 1,859 cases, comprising 1,098 (59.1%) boys and 761 (40.9%) girls, were included in the study. Of these cases, 327 (17.6%) were obese, and 1,532 (82.4%) were of normal weight. According to ABPM data, 30.7% of all cases were normotensive. Additionally, the rate of HT in obese subjects (79.2%) was significantly higher than in non-obese subjects (67.2%). Logistic regression analysis of the study showed that older age, obesity, and being in the diastolic non-dipper group were associated with a higher risk of invalid measurement.Conclusion: This study emphasizes the high prevalence of white coat HT in children in our region, despite the difficulties related to measurement adequacy, and thus highlights the importance of using ABPM in the diagnosis and follow-up of hypertension.Öğe Hemodiafiltrasyon ile hızlıca tedavi edilen bizmut zehirlenmesine bağlı akut böbrek hasarı: güncelleme ve olgu tartışması(İnönü Üniversitesi Tıp Fakültesi Dergisi, 2013) Elmas, Ahmet Taner; Tabel, YılmazOn altı yaşında kız hasta bulantı ve kusma yakınmaları ile acil servisimize başvurdu. Öyküsünden, 7 gün önce intihar amaçlı 35 adet De-Nol tablet (10,5 gr kolloidal bizmut subsitrat) aldığı öğrenildi. Başvuru anındaki fizik muayene bulguları normal olarak değerlendirildi. Laboratuar tetkiklerinde; BUN 76 mg/dl, kreatinin 19.2 mg/dl ve serum bizmut düzeyi 395 µg/lt idi. Hastaya sıvı ve elektrolit tedavisi, hemodiyaliz tedavisi ve şelatör ajan olarak penisilamin tedavileri başlandı. Daha sonra, 72 saat süreyle sürekli venö-venöz hemodiyafiltrasyon tedavisi uygulandı. Üç günlük hemodiyafiltrasyon tedavisi sonunda BUN: 14 mg/dl ve serum kreatinin düzeyi 0.78 mg/dl’ye geriledi. Penisilamin tedavisinin 14. gününde serum bizmut düzeyi 32 µg/L’ye düştü. Bu vaka; kolloidal bizmut subsitrat intoksikasyonu sonucu gelişen akut böbrek hasarının tedavisinde hemodiyaliz yan etkileri gözlendiğinde hemodiyafiltrasyonun alternatif bir tedavi yöntemi olabileceğini göstermiştir.Öğe Hypertension in Children with Unilateral Multicystic Dysplastic Kidney: A Common but Rarely Diagnosed Condition(Aves, 2022) Elmas, Ahmet Taner; Selcuk, Senay Zirhli; Tabel, YilmazObjective: In this study, we aimed to determine the frequency of hypertension by performing 24 hours ambulatory blood pressure monitoring in children with unilateral multi-cystic disease of kidney without ipsilateral and/or contralateral kidney and/or urinary system anomalies. Methods: This study enrolled 24 patients with unilateral multi-cystic disease of kidney and age- and height-matched 20 healthy children. Blood pressure was measured by 2 approaches as follows: manual blood pressure and ambulatory blood pressure monitoring. Day-time, night-time, and 24 hours heart rate, pulse pressure, systolic and diastolic blood pressure, median arterial pressure, and systolic and diastolic blood pressure loads (%) were compared. Results: Ambulatory blood pressure monitoring measurements showed the presence of masked hypertension in 12 patients (45.8%), although 2 (8.3%) unilateral multi-cystic disease of kidney patients were hypertensive with manual blood pressure measurements. We detected that systolic blood pressure loads (%) (day-time, night-time, and 24 hours) and disatolic blood pressure loads (%) (night-time and 24 hours) were considerably higher than those of healthy children (P =.030, P =.012, P =.005, P =.012 and P =.005, respectively). Conclusion: Children with unilateral multi-cystic disease of kidney are more likely to have masked hypertension. Manual blood pressure measurements are not accurate in ruling out hypertension in children with unilateral multi-cystic disease of kidney. Ambulatory blood pressure monitoring contributes to more susceptible outcomes in proportion to manual blood pressure measurement in these patients, and it should be considered in clinical practice instead of manual blood pressure measurements.Öğe A hypertensive girl with failure to thrive accompanied by gastrointestinal symptoms: Answers(Springer, 2021) Selcuk, Senay Zirhli; Elmas, Ahmet Taner; Yildirim, Ismail Okan; Sigirci, Ahmet; Sozeri, Betul; Tabel, Yilmaz[Abstract Not Available]Öğe A hypertensive girl with failure to thrive accompanied by gastrointestinal symptoms: Questions(Springer, 2021) Selcuk, Senay Zirhli; Elmas, Ahmet Taner; Yildirim, Ismail Okan; Sigirci, Ahmet; Sozeri, Betul; Tabel, Yilmaz[Abstract Not Available]
