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Öğe Can Displaced Whole Zygomatic Bone as Bone Graft Be Reused for Zygomatic Bone Defect in a Neglected Tetrapod Fracture?(Lippincott Williams & Wilkins, 2011) Coban, Yusuf Kenan; Tenekeci, Goktekin; Elmas, Omer[Abstract Not Available]Öğe Comparison of the effects of PRP and hyaluronic acid in promoting peripheral nerve regeneration An experimental study with vascular conduit model in rats'(Edizioni Luigi Pozzi, 2016) Firat, Cemal; Aytekin, Ahmet Hamdi; Durak, Mehmet Akif; Geyik, Yilmaz; Erbatur, Serkan; Dogan, Metin; Elmas, OmerAIM: Peripheral nerve defects generally occur due to mechanical, chemical, thermal and pathologic causes and the reconstruction is still a challenging problem. In the present study, we aimed to compare the effects of platelet rich plasma (PRP) that has high levels of growth factors and hyaluronic acid (HA) that is known to have positive effects on nerve regeneration by decreasing scar formation in a rat model where they were injected through allogeneic aorta graft in peripheral nerve defects using histopathologic and functional methods. MATERIAL AND METHODS: The study involved 20 Wistar Albino male rats that weighed 200 to 250 grams and aged about 1 year old. Of the rats, two were used as donor for PRP and aorta graft harvest. Three random groups of 6 rats were composed. In all of the groups, the left sciatic nerves were used and 1 cm of defects were created. The right sciatic nerves were used as control groups. Group I was the group repaired with autograft, Group 2 was the group repaired with HA injected through aorta graft and Group 3 was the group repaired with PRP injected through aorta graft. The findings were evaluated in terms of functional (electromyography and walk test analysis) and histopathologic parameters at 12 weeks. RESULTS: In all of the groups varying degrees of axonal regeneration was observed. Group I was the closest group to the control group showing highest rate of nerve regeneration followed by Group 3 where PRP was injected through aorta graft and group 2 where ha was used respectively. CONCLUSION: The study demonstrates that PRP enhances peripheral nerve regeneration more than HA when used in a vascular conduit model.Öğe Radiological and Histopathological Evaluation in Reduction Mammoplasty(İnönü Üniversitesi, Tıp Fakültesi, Plastik Rekonstrüktif ve Estetik Cerrahi Anabilim Dalı, Malatya, Türkiye, 2013) Kilinc, Hidir; Elmas, Omer; Bilen, Bilge TurkRadiological and Histopathological Evaluation in Reduction Mammoplasty Öz: Amaç: Mammografi ve Ultrasonografi (USG), redüksiyon mammoplasti öncesinde asemptomatik lezyonların tespit edilmesinde yardımcı tanı yöntemleridir. Ancak preoperatif radyolojik değerlendirme her zaman kesin sonuçlar vermemektedir. Bu nedenle premalign lezyonların veya sessiz kanser odaklarının tanısı amacıyla, preoperatif radyolojik inceleme ve postoperatif histopatolojik değerlendirme birlikte kullanıldı. Gereç ve Yöntemler: Kliniğimizde, 2007-2011 yılları arasında 135 hastada radüksiyon mammoplasti ameliyatı yapıldı. Hastaların yaşları 18 ile 67 arasında değişmekteydi (ortalama 44,6 yıl). Operasyondan önce tüm hastalarda USG ve 40 yaş üstündeki hastalarda ek olarak mammografi yapıldı. Çıkarılan tüm doku örnekleri histopatolojik olarak incelendi. Bulgular: Preoperatif olarak yapılan radyolojik incelemede; 96 hastada (%71,1) USG sonuçları normal olarak değerlendirildi. %8,1 Fibrokistik değişiklik, %0,7 lipoma, %4,4 fibroadenoma, %2,9 benign lenf nodu olduğu tespit edildi. Histopatolojik olarak yapılan incelemede; %7 hafif-orta epitelyal hiperplazi, %4,8 ağır epitelyal hiperplazi, %25,9 fibrokistik değişiklik, %16,2 fibrozis, %9,6 yağdan zengin meme dokusu, %7,7 apokrin metaplazi, %4,4 duktal ektazi, %3,7 fokal adenozis, %4,4 hafif-orta dereceli duktal hiperplazi, %3,7 fibroadenoma ve %12,2 normal meme dokusu olarak değerlendirildi. Sonuç: Bu çalışmada, meme dokusu örneklerinde %87,6 oranında non-proliferatif benign değişiklikler olduğu görüldü. Premalign veya malign lezyona rastlanmadı. Bu sonuçlar, preoperatif radyolojik değerlendirme ve postoperatif histopatolojik incelemenin, memenin benign, premalign veya sessiz malign lezyonlarının tanısındaki önemini göstermesi açısından anlamlı bulundu.Öğe Radiological and Histopathological Evaluation in Reduction Mammoplasty(İnönü Üniversitesi Tıp Fakültesi Dergisi, 2013) Kilinc, Hidir; Elmas, Omer; Bilen, Bilge TurkAim: Mammography and ultrasonography are helpful diagnostic methods for the detection of asymptomatic lesions prior to reduction mammoplasty operations. Preoperative radiological evaluation does not give accurate results all time. Consequently, preoperative radilological and postoperative histopathologic evaluation were used together in order to diagnose the premalignant and silent cancer foci. Material and Methods: In our clinic, 135 patients underwent reduction mammoplasty operation between 2007 and 2011. The age of the patients ranged from 18 to 67 (mean 44.6). Ultrasonography was performed for all the patients and mammography was performed additionally for the ones older than 40 years of age. The excised tissue samples were sent for histopathologic evaluation. Results: Preoperative radiologic evaluation, USG results were assessed as normal in 96 patients (71,1%) and, of the patients, % 8,1 had fibrocystic changes, 0,7% had lipoma, 4.4% had fibroadenoma and 2,9% had benign lymph node. In the histopathologic evaluation, 7% had mild epithelial hyperplasia, 4,8% had severe epithelial hyperplasia, 25,9% had fibrocystic changes, 16.2% had fibrosis, 9,6% had fatty breast tissue, 7,7% had apocrine metaplasia, 4,4% had ductal ectasia, 3,7% had focal adenosis, 4,4% had mild ductal hyperplasia, 3,7% had fibroadenoma and 12,2% had normal breast tissue. Conclusion: In this study, non-proliferative benign changes were seen in the 87,6% of the breast tissue samples. No premalignant or malignant lesions were detected. These results revealed that preoperative radiologic evaluation and postoperative histopathologic analysis were significant in terms of diagnosis of benign, premalignant or silent malignant lesions of the breast.
