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    Relation of susceptibility-weighted imaging findings with histological grade in intracranial meningiomas
    (2021) Er, Ali; Bozdag, Mustafa
    Aim: We aimed to investigate the relation of susceptibility-weighted imaging (SWI) findings with histological grade in intracranial meningiomas. Materials and Methods: Histopathologically confirmed 58 intracranial meningioma patients (48 typical (low-grade meningioma), 10 atypical (high-grade meningioma)) who had undergone preoperative SWI between 2015 and 2020 were retrospectively evaluated. Tumor size, location, presence of peritumoral edema, WHO grade, low-grade meningioma subtypes and Ki-67 proliferation indexes were noted. SWI findings of intracranial meningiomas were categorized as either positive or negative based on presence/absence of intratumoral susceptibility signals (ITSSs). The origin of ITSSs in SWI-positive meningiomas was assessed with phase images and classified as calcification (SWI-C), vascular structure (SWI-V) or hemorrhage (SWI-H). Mann-Whitney U, chi-square, Fisher’s exact tests and multiple logistic regression analyses were performed for statistical assessment. Results: There was a significant association between SWI-positivity and low-grade in meningiomas (p = 0.010). A higher incidence of calcification was found in low-grade meningiomas (%60 in low-grade vs %10 in high-grade). Peritumoral edema was found to be associated with high grade in meningiomas (p = 0.032). Ki-67 proliferation index was significantly higher in high-grade meningiomas compared to low-grade. (p = 0.000). Conclusion: SWI combined with peritumoral edema may help to predict high grade in intracranial meningiomas.
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    Relationship between degenerative medial meniscus lesions and the medial fat tissue thickness of the knee
    (2021) Kacmaz, Ismail Eralp; Uzakgider, Meliksah; Basa, Can Doruk; Zhamilov, Vadym; Er, Ali; Reisoglu, Ali
    Aim: It was aimed to investigate the relationship between fatty tissue thickness in the medial of the knee and degenerative meniscus lesion.Materials and Methods: Images of 300 patients (151 females and 149 males) who had previously taken knee magnetic resonance imaging (MRI) were evaluated retrospectively. The relationship between medial meniscus degenerative lesion (MMDL) and age, sex, side, height, weight, body mass index (BMI), medial fat thickness (MFT), length of medial tibial plateau (MTP) was investigated.Results: Mean age of 300 patients (144 rights, 156 left knees) was 41.4 ± 11.8 (range 18–67) years and 200 of them had degenerative meniscus lesions, 100 of them were not detected.Age, weight, height, BMI, MFT, MTP, and MFT/MTP were all correlated with the presence of an MMDL, and the strongest relationship was with age (p0.001). No significant relationship between weight and MMDL was found. However, both MFT and the MFT/MTP ratio were more strongly correlated with the presence of an MMDL. Logistic regression analysis indicated that the presence of an MMDL was 25 times more likely in patients with a high MFT/MTP ratio (odds ratio, 0.040).Conclusion: In this study, the MFT / MTP ratio was found higher in patients with medial meniscus degenerative lesions than in the healthy population. This study shows that fatty tissue thickness in the medial of the knee can be effective in the formation of degenerative meniscus lesions, as well as BMI. However, this study may form the basis for prospective studies in which factors such as daily activity, profession and sports level are also investigated to create a clearer judgment.