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    3D Micro-CT Analysis of Void and Gap Formation in Curved Root Canals
    (NLM (Medline), 2017) Şımşek N.; Keleş A.; Ahmetoğlu F.; Akinci L.; Er K.
    Objective: This study used microcomputed tomography (micro-CT) to compare the volumes of voids and gaps in curved root canals instrumented and filled using various techniques. Methods: Twenty extracted mandibular first molars with two curved mesial root canals were used. Root canals were instrumented using a self-adjusting file (SAF) or Revo-S file system. For standardization, mesiobuccal canals were instrumented with SAF and mesiolingual canals were instrumented with Revo-S in each root. The canals were divided into four experimental groups (n=10 in each). The canals were then filled via cold lateral compaction (CLC) or a thermoplasticized injectable technique (TT) using gutta-percha and AH Plus root canal sealer. The roots were scanned with a micro-CT, and the volumes of the voids and gaps were calculated using three-dimensional (3D) micro-CT images. Data were analyzed using unpaired t- and Kruskal-Wallis tests. A value of P<0.05 was considered significant. Results: None of the tested techniques provided void- or gap-free fillings. Nevertheless, the SAF showed more gap formation than the Revo-S, and TT showed higher gap formation in all experimental groups. These differences, however, were not statistically significant (P>0.05). Conclusion: The SAF and Revo-S rotary file systems yielded comparable results. No statistically significant difference was found between the results of the various instrumentation and filling techniques. Copyright: © 2020 European Endodontic Journal.
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    Lesion sterilization and tissue repair
    (Cumhuriyet University Faculty of Dentistry, 2014) Şimşek N.; Özan U.; Er K.
    Success of the endodontic treatment depends on the microbial elimination in the root canal and periradicular region. Mechanic instrumentation alone cannot achieve a sterile condition. For this reason, some researchers have tried to solve this problem with local administration of antibiotic mixtures. Triple antibiotic paste containing metronidazole, ciprofloxacin, and minocycline has been reported to be a successful protocol in controlling the root canal pathogens. The developed treatment method have been named lesion sterilization and tissue reapir. The purpose of this review is to make contribution to beter understanding of biocompatibility, efficiency, and the restricted properties of the triple antibiotic paste in endodontic therapy and pulp revascularization.