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  • Küçük Resim
    Öğe
    Evaluating the effects of two different lipid emulsions on morbidities in premature infants
    (2021) Ercin, Secil; Coskun, Yesim; Deliloglu, Burak; Bilgin, Leyla
    Aim: The aim of this study is to evaluate the effect of OO and FO based LEs on morbidities in preterm infants. Materials and Methods: A total of 44 neonates with a gestation ≤32 weeks were included in this retrospective observational study. The study group composed of neonates (n=28) who received SMOFlipid and the control group consisted of infants (n=16) who received ClinOleic. Demographic and clinical data of the neonates in terms of duration of PN, respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD), ), duration of mechanical ventilation (MV), patent ductus arteriosus (PDA), necrotizing enterocolitis (NEC), intraventricular hemorrhage (IVH), retinopathy of prematurity (ROP), PN-associated cholestasis (PNAC) and plasma triglyceride (TG) levels (mg/dl) were collected and compared statistically. Results: We did not find significant difference in terms of RDS, BPD, NEC, IVH, ROP and PNAC. The study group had lower TG levels than the control group which were 93.03±24.55 mg/dL and 151.31±114 mg/dL, respectively (p=0.002). Conclusion: Both LEs are well tolerated and safe without any side effects in preterm infants. Although both LEs have no significant effect on morbidities, FO based LE provide better TG levels than OO based LEs.
  • Küçük Resim
    Öğe
    Use of silver-impregnated umbilical venous catheters for prevention of catheter associated bloodstream infection in neonates
    (2021) Coskun, Yesim; Kayas, Kalender; Ercin, Secil; Gursoy, Tugba
    Aim: Neonates hospitalized in neonatal intensive care units (NICU)s often require a venous access. Umbilical venous catheter (UVC) is the commonly used one. UVCs are known to cause life-threatening complications such as catheter-associated bloodstream infections (CABSI). To the best of our knowledge, our unit is the first and only NICU in Turkey that used silver-impregnated UVCs. This study aims to evaluate the impact of silver-impregnated UVC insertion on the incidence of CABSI. Materials and Methods: A total of 108 patients were included in this retrospective study. After the application of exclusion criteria, the control group was composed of neonates (n=58) who had polyurethane (PU) UVCs inserted and the study group consisted of infants (n=41) who had silver-impregnated UVCs inserted. Demographic and clinical data of the mothers and neonates including duration of UVC insertion and sepsis incidence were collected and compared statistically. Results: There was no statistically significant difference between the groups except for intubation period and mortality. One neonate in each group had CABSI (p=1). Four neonates, two in each group, were diagnosed with clinical sepsis. Total CABSI incidence in our whole population was 2% and 3.3 per 1000 catheter days. Conclusion: Strict precautions should be taken to prevent infection in every unit. In NICUs with low incidence of sepsis, silver-impregnated UVCs may have no further effect in the reduction of CABSI.