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    A case of paralytic rabies mimicking Guillain-Barre syndrome
    (Turgut Özal Tıp Merkezi Dergisi, 2016) Erdoğan, Seher; Göktepe, Ahmet Rauf; Bosnak, Mehmet; Dai, Alper
    Abstract Rabies is an acute, fatal viral infection of the central nervous system, and one of the oldest zoonotic diseases in human history. A Syrian boy aged 14 had been hospitalized for 2 days with a preliminary diagnosis of Guillain-Barre syndrome because of muscle weakness that spread rapidly to the upper extremities. He was transferred to our unit when the muscle weakness worsened. Respiratory failure developed following admission to the ICU, and the patient was intubated and given ventilator support. Ascending paralysis and albuminocytologic dissociation in the cerebrospinal fluid (CSF) examination suggested a preliminary diagnosis of Guillain-Barre syndrome and plasmapheresis treatment was initiated. No clinical improvement was achieved despite plasmapheresis. On the 10th day of hospitalization, we learned that he had been bitten on the ankle by a stray dog in Syria 2 months ago and had not received prophylaxis. Suspecting that this might be a case of rabies, body fluid samples of the patient were sent to the National Reference Laboratory. The patient died on the 12th day of admission. A postmortem brain biopsy was taken, and Negri bodies were detected. This case report emphasizes that rabies should be considered in the differential diagnosis of patients presenting with paralysis. Keywords: Rabies; Guillain-Barre Syndrome; Encephalomyelitis.
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    A case of seckel syndrome with human bocavirus infection and respiratory failure
    (Turgut Özal Tıp Merkezi Dergisi, 2016) Erdoğan, Seher; Oto, Arzu; Boşnak, Mehmet
    Abstract Human bocavirus (HBoV) is a newly described member of the family parvovirus. We report an 18 -month-old male patient under observation with a diagnosis of Seckel syndrome and presenting to our emergency department with respiratory distress was admitted to the pediatric intensive care unit. Oxygen saturation with non-rebreather mask was 93%. The patient was intubated due to respiratory insufficiency and respirated on a mechanical ventilator. HBoV was isolated in a nasopharyngeal specimen usıng PCR. Antimicrobial and antiviral theraoy was started. The patient’s blood pressure fell, dopamine infusion was started. Hypotension persisted, and noradrenalin was added to treatment. Hypotension persisted, and the patient died on the 4th day of hospitalization. The purpose of this case report is to emphasize the need to remember HBoV infections in cases of respiratory failure, particularly under the age of 5, and that although the condition is rare in the literature, intensive care may still be required. Keywords: Seckel Syndrome; Human Bocavirus; Child.