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Öğe Antifungal activity of microbial chondroitin sulfate against Candida albicans(2020) Ünver, Tuba; Erenler, Ayşe Şebnem; Melekoğlu, Rauf; Akpolat, Nusret; Seçkin, Turgay; Azimov, Raul; Özaslan, Fatma BaharAbstract: A vaginal yeast infection called vaginal candidiasis is the most commonly seen type of Candida infections with a rate of 37%. Vaginal candidiasis affects three fourth (75%) of women in their lifetimes, and this is the most common cause of women seeking gynecological care. Vaginal candidiasis can result in serious symptoms such as discharge, itching, burning sensation, pain, rash and irritation in the vagina and vulva. Candida albicans, in particular, is the most common cause of vaginal candidiasis. Therefore, the treatment and control process of Candida species is very important in terms of health. In this study, as a first step, Microbial Chondroitin Sulfate was produced from Escherichia coli C2987 strain by using a specific microbial system and reliable biotechnological methods. After that, the efficacy of Microbial CS as an antifungal agent on C. albicans strains was tested by using the agar dilution method. As a result, it was determined that the Microbial CS was particularly effective against the yeasts C. albicans, and the minimum inhibitory concentration of Microbial CS was 0.32 g/mL. Our findings showed that Microbial CS can be used in the content of various biomedical products that can be used as an antifungal agent for Candida sp. Microbial CS can also be used to treat the disease alone or to support the treatment that increases the efficacy of antibiotics.Öğe The Effect of Electrode Type on Energy Efficiency in Microbial Fuel Cells Using vgb Recombinant Enterobacter aerogenes(Adıyaman Üniversitesi Fen Bilimleri Dergisi, 2019) Erenler, Ayşe ŞebnemÖz: In this study, microbial fuel cells were designed using E. aerogenes, an important proton producing bacterium, to determine energy efficiency. In the design of these fuel cells, nafion membrane is preferred as a proton permeable membrane. Potassium ferricyanide was used in the cathode section when the anode partition mediator was prefered as methylene blue. Within the scope of the study, the efficiency of the electrode route on the optimization and energy efficiency of fuel pellets prepared using E. aerogenes was determined. A comparative study was carried out using graphite, composite and copper electrodes as the electrode type. In the experiment with copper electrode, the highest voltage value was read as 0.23 V, 0.38 V on the composite electrode and 0.52 V on the carbon electrode. It is determined that the electrode giving the highest voltage is the carbon electrode. Furthermore, optimization of designed microbial fuel cell’s nutrient, pH and microorganism incubation time has been realized.Öğe The Effect of Electrode Type on Energy Efficiency in Microbial Fuel Cells Using vgb+ Recombinant Enterobacter aerogenes(2019) Erenler, Ayşe ŞebnemAbstract: In this study, microbial fuel cells were designed using E. aerogenes, an important proton producing bacterium, to determine energy efficiency. In the design of these fuel cells, nafion membrane is preferred as a proton permeable membrane. Potassium ferricyanide was used in the cathode section when the anode partition mediator was prefered as methylene blue. Within the scope of the study, the efficiency of the electrode route on the optimization and energy efficiency of fuel pellets prepared using E. aerogenes was determined. A comparative study was carried out using graphite, composite and copper electrodes as the electrode type. In the experiment with copper electrode, the highest voltage value was read as 0.23 V, 0.38 V on the composite electrode and 0.52 V on the carbon electrode. It is determined that the electrode giving the highest voltage is the carbon electrode. Furthermore, optimization of designed microbial fuel cell’s nutrient, pH and microorganism incubation time has been realized.Öğe vgb+ Rekombinant Enterobacter aerogenes Kullanılan Mikrobiyal Yakıt Pillerinde Enerji Verimliliği Üzerine Elektrot Türünün Etkisi(2019) Erenler, Ayşe ŞebnemAbstract:In this study, microbial fuel cells were designed using E. aerogenes, an important proton producing bacterium, to determine energy efficiency. In the design of these fuel cells, nafion membrane is preferred as a proton permeable membrane. Potassium ferricyanide was used in the cathode section when the anode partition mediator was prefered as methylene blue. Within the scope of the study, the efficiency of the electrode route on the optimization and energy efficiency of fuel pellets prepared using E. aerogenes was determined. A comparative study was carried out using graphite, composite and copper electrodes as the electrode type. In the experiment with copper electrode, the highest voltage value was read as 0.23 V, 0.38 V on the composite electrode and 0.52 V on the carbon electrode. It is determined that the electrode giving the highest voltage is the carbon electrode. Furthermore, optimization of designed microbial fuel cell’s nutrient, pH and microorganism incubation time has been realized.