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    Detection of intracavitary lesions in 436 infertile women by office hysteroscopy and comparison with histopathology results
    (2021) Colak, Eser; Zeyneloglu, Hulusi; Ozcimen, Emel Ebru; Eroglu, Semra
    Aim: To examine the importance of office hysteroscopy in detecting and treating endometrial pathologies of infertile patient groups.Materials and Methods: For this retrospective observational study, first, electronic hospital records were examined in order to identify patients who underwent office hysterescopy at our clinic, between 2003 and 2020, for infertility. The office hysteroscopy findings of 436 patients were included in the study, and examined and compared with the histopathological results.Results: The age distribution of the patients included in the study was homogeneous in terms of group variances. Thehysteroscopy findings of the patients were as follows: normal cavityin 137 patients(31.4%), endometrial polyps in 199 patients(45.6%), synechia in 14 patients(3.2%), subseptum or arcuate uterus in 32 patients (7.3%), t-shaped uterus in 28 patients (6.4%), cervical polyps in 6 patients (1.4%), Asherman’s syndrome in 6 patients (1.4%), and submucous myoma in 14 patients (3.2%). The most frequently detected lesion with office hysteroscopy was polyps,at a rate of 47% with 205 patients. In the pathology results, of the 137 patients who were diagnosed with normal endometrium via office hysteroscopy and underwent biopsy, 119were reported as normal (89.6%), while 6 were diagnosed with polyps (4.4%). The sensitivity and specificity of office hysteroscopy in detecting endometrial polyps were 94% and 56%, respectively.Conclusion: Office hysteroscopy may be one of the first alternative methods that can be used for safe and practical outpatient diagnosis and treatment in infertile patient groups.
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    Frequency and genotype distribution of high-risk human papilloma virus types in Karabuk province, Turkey: A hospital based cross-sectional study
    (2020) Eroglu, Semra; Asgin, Nergis
    Aim: In this cross-sectional study, we aimed to determine the prevalence and genotype distribution of high-risk human papillomavirus (HPV; HR-HPV) infection in patients admitted to the gynecology and obstetrics outpatient clinics of Karabuk University Training and Research Hospital.Material and Methods: A total of 402 women aged 18–65 years who were admitted to the gynecology and obstetrics Clinic, Karabuk University Training and Research Hospital, between October 2016 and June 2019 were included. The presence of HR-HPV and genotyping of HPV were investigated using real-time polymerase chain reaction in cervical swab samples.Results: HR-HPV infection was found in 23.9% of women. HR-HPV positivity was detected most commonly in the age group of 20–29 years. Regarding genotype distribution among HPV-positive women, the genotypes that included multiple HR-HPV infections (mixed HR-HPV) were the most common genotype (38.5%), followed by HPV-16 (13.1%) and HPV-52 (9.8%).Conclusion: Prevalence of HR-HPV infection was found to be high in our region, with the most commonly observed genotypes being those containing mixed HR-HPV. We believe that these results would be helpful during the selection of primary and secondary preventive measures for cervical cancer while planning vaccination and screening programs.