Yazar "Esener, Burak" seçeneğine göre listele
Listeleniyor 1 - 5 / 5
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Efficacy of dexamethasone implant in the treatment of macular edema due to different etiologies(2020) Öztürk, Emrah; Esener, Burak; Gündüz, AbuzerAbstract: Purpose: The aim of this study was to evaluate the effectiveness of intravitreal DEX implant injection in the treatment of macular edema due to four different etiologies. Materials and Methods: This is a retrospective and case control study. A total of 177 patients who underwent intravitreal DEX implant between 2014 and 2018 for four different etiologies, which are diabetic retinopathy (DR), branch retinal vein occlusion (BRVO), central retinal vein occlusion (CRVO) and posterior uveitis (PU), were included in the study. Best-corrected visual acuity (BCVA) and central macular thickness (CMT) were evaluated in pre-injection, 1st, 3rd, and 6th months post-injection. Results: Eighty-one patients (45.8%) had DR, 44 (24.9%) had BRVO, 35 (19.8%) had CRVO, and 17 (9.6%) had PU. There was a statistically significant difference in BCVA in the DR, BRVO and PU groups after the injection, but no significant difference was observed in the CRVO group. It is observed that there was a statistically significant decrease in CMT in all groups after the injection. The change in CMT in the 1st month was 153.4 ± 137 µm in the DR group, 161.1 ± 151 µm in the BRVO, 270.5 ± 189 µm in the CRVO and 142.2 ± 174 µm in the PU group. Conclusion: The intravitreal DEX implant reduces the CMT in patients with macular edema secondary to various etiologies and improves BCVA in patients with macular edema secondary to various etiologies except for patients with CRVO.Öğe Posterior reversible encephalopathy syndrome secondary to preeclampsia-a case report(2019) Esener, Burak; Ulucan Ataş, Pamuk Betul; Fırat, Penpe GülAbstract: In this article, we aimed to present a 29 year-old preeclampsia patient with sudden loss of vision in both eyes after cesarean section. In her ophthalmoscopic examination her visual acuity was at the level of light perception on both of eyes. The anterior segment examination of the patient was normal with normal eye movement in all directions. The fundus had a tilted disc, which was evident on the left. Emergency orbital, cranial MRI, carotid Doppler were requested with arterial blood pressure control of the patient. Close follow-up was recommended. Patient was diagnosed as posterior reversible encephalopathy syndrome with cortical visual loss due to vasogenic edema according to diffusion MRI result. Patient’s visual acuity was 10/10 on the right side and 16/100 on the left side after 3 days with control of arterial blood pressure.Öğe Posterior reversible encephalopathy syndrome secondary to preeclampsia-a case report(2019) Esener, Burak; Ulucan Atas, Pamuk Betul; Firat, Penpe GulIn this article, we aimed to present a 29 year-old preeclampsia patient with sudden loss of vision in both eyes after cesarean section. In her ophthalmoscopic examination her visual acuity was at the level of light perception on both of eyes. The anterior segment examination of the patient was normal with normal eye movement in all directions. The fundus had a tilted disc, which was evident on the left. Emergency orbital, cranial MRI, carotid Doppler were requested with arterial blood pressure control of the patient. Close follow-up was recommended. Patient was diagnosed as posterior reversible encephalopathy syndrome with cortical visual loss due to vasogenic edema according to diffusion MRI result. Patient’s visual acuity was 10/10 on the right side and 16/100 on the left side after 3 days with control of arterial blood pressure.Öğe Structural evaluation in inherited retinal diseases(Bmj Publishing Group, 2021) Varela, Malena Daich; Esener, Burak; Hashem, Shaima A.; de Guimaraes, Thales Antonio Cabral; Georgiou, Michalis; Michaelides, MichelOphthalmic genetics is a field that has been rapidly evolving over the last decade, mainly due to the flourishing of translational medicine for inherited retinal diseases (IRD). In this review, we will address the different methods by which retinal structure can be objectively and accurately assessed in IRD. We review standard-of-care imaging for these patients: colour fundus photography, fundus autofluorescence imaging and optical coherence tomography (OCT), as well as higher-resolution and/or newer technologies including OCT angiography, adaptive optics imaging, fundus imaging using a range of wavelengths, magnetic resonance imaging, laser speckle flowgraphy and retinal oximetry, illustrating their utility using paradigm genotypes with on-going therapeutic efforts/trials.Öğe Yaşa bağlı makula dejenerasyonu gelişiminde HIF1A, TGFA ve TGFB3 genlerinin belirli varyantlarının araştırılması(İnönü Üniversitesi, 2021) Esener, Burak; Dı?kcı?, SeyhanAmaç: YBMD ile HIF1A, TGFA ve TGFB3 genlerinin belirli varyantları arasındaki ilişkiyi değerlendirmektir. Gereç ve Yöntem: Bu prospektif, kesitsel çalışmaya Mart 2020 ve Mart 2021 tarihleri arasında İnönü Üniversitesi Tıp Fakültesi Göz Hastalıkları Ana Bilim Dalı'nda muayene edilen yaş tip YBMD'si olan 83, kuru tip YBMD'si olan 39 hasta ile kontrol grubu olarak yaş ve cinsiyet uyumlu 68 birey alındı. Tüm olguların tam göz muayenesi yapıldı. YBMD tanısı oftalmolojik muayene, optik koherens tomografi ve fundus floresein anjiografi bulgularına göre konuldu. Her bir olgudan DNA izolasyonu yapılmak üzere 2ml periferik venöz kan örneği EDTA'lı kan tüpüne alındı. HIF1A geni rs11549465 ve rs11549467 varyantları, TGFA geni rs2166975 ve rs1058213 varyantları ile TGFB3 geni IVS5+104AG varyantı PCR-RFLP yöntemi ile araştırıldı. Bulgular: Çalışmaya alınan olguların ortalama yaşı yaş tip YBMD grubunda 70,9 ± 5,91 yıl, kuru tip YBMD grubunda 70,59 ± 6,87 yıl iken kontrol grubunda ise 69,4 ± 5,56 yıldı (p>0,05). Yaş tip YBMD grubunda 51 (%61,4) erkek ve 32 (%38,6) kadın, kuru tip YBMD grubunda 23 (%59,0) erkek ve 16 (%41,0) kadın, kontrol grubunda ise 39 (%57,4) erkek ve 29 (%42,6) kadın bulunmaktaydı (p>0,05). Çalışmaya dahil edilen gözlerin median EDGK değerleri yaş tip YBMD grubunda 1,3 logMAR (0,05 - 3,10), kuru tip YBMD grubunda 0,52 logMAR (0,00 - 3,10), kontrol grubunda ise 0,15 logMAR (0,00 - 1,30) olarak belirlendi. (p<0,05). Median EDGK yaş tip YBMD'de en kötüyken kontrol grubunda en iyiydi. Gruplar arasında HIF1A geni rs11549465 ve TGFB3 geni IVS5+104AG polimorfizmine özgü genotipler arasında istatistiksel olarak anlamlı fark saptandı. TGFA geni rs2166975 ve rs1058213 polimorfizmleri için ise gruplar arasında istatistiksel olarak anlamlı fark izlenmedi (p>0,05). Olguların hiçbirinde HIF1A geni rs11549467 polimorfizmi görülmemiştir. Sonuç: Yaş tip ve kuru tip YBMD gruplarında kontrol grubuna göre HIF1A geni rs11549465 varyantı ile TGFB3 geni IVS5+104AG varyantı daha fazla saptanmıştır. Bu sonuç bu varyantların YBMD riskinin artışıyla ilişkili olabileceğini düşündürmektedir. Anahtar kelimeler: HIF1A, TGFA, TGFB3, Yaşa Bağlı Makula Dejenerasyonu
