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    Effects of Home-Based Aerobic Exercise Training on Glycemic Control and Lipid Profiles in Patients with Prediabetes and Type 2 Diabetes: A Randomized Controlled Study
    (AVES, 2021) Özdemir F.; Kilcik M.H.; Evren B.; Şahin I.; Çolak C.
    Objective: Diabetes is an important health condition; in recent years, its prevalence has increased dramatically. This study aimed to evaluate the effects of home-based aerobic exercise training on glycemic control and lipid profiles in patients with prediabetes and type 2 diabetes. Material and Methods: This study included a total of 65 patients with ages between 38 and 66 years. The participants were divided into prediabetes exercise group (group I, n = 17), prediabetes control group (group II, n = 17), type 2 diabetes exercise group (group III, n = 17), and type 2 diabetes control group (group IV, n = 14). Home-based aerobic exercise training was suggested to all individuals in exercise groups (30 min, 60% of maximum heart rate [220 beats/min minus their age], 3 days per week) by a physiotherapist. Results: Among the patients, 61.5% were male and 38.5% were female. Participants’ sociodemographic characteristics, such as age, sex, and body mass index values, were similar (P > .05). After follow-up, the fasting plasma glucose (FPG) and high-density lipoprotein cholesterol (HDL_C) values were different in group I (P < .05). However, there were no differences in group II (P > .05). Hemoglobin A1c, HDL_C, FPG, and postprandial plasma glucose variables showed significant differences in group III (P < .05). There was a significant difference only in FPG levels in group IV (P < .05). Conclusion: Home-based exercise program is important for improving the patient’s self-control of diabetes. However, patients need physiotherapy counseling for sustainable home-based exercise training. © 2021 AVES. All Rights Reserved.
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    Evaluation of prediabetes patients in terms of metabolic syndrome
    (Verduci Editore s.r.l, 2024) Genc S.; Evren B.; Aydin M.N.; Sahin I.
    – OBJECTIVE: Prediabetes accompanied by metabolic syndrome accelerates the process leading to diabetes and causes an increase in complications. The current study aimed to investigate the clinical conditions accompanying prediabetes and the effect of the association of metabolic syndrome on clinical outcomes in prediabetics. SUBJECTS AND METHODS: This cross-sectional study was conducted with 88 prediabetic individuals between November 2022 and January 2023. Prediabetes was diagnosed using the American Diabetes Association (ADA) criteria, and metabolic syndrome was diagnosed using the International Diabetes Federation criteria. Clinical history, physical examination and laboratory tests of the participants were recorded. RESULTS: Metabolic syndrome (MetS) was present in 69 of 88 prediabetic patients included in the study (78.4%). Hypertension (p=0.019), abdominal obesity (p<0.001), low-density lipoprotein (LDL) elevation (p=0.006), and dyslipidemia (p=0.020) were detected more frequently in prediabetic individuals accompanied by MetS. Median values of waist circumference (p=0.020), systolic blood pressure (p=0.021), triglyceride (p<0.001), LDL (p=0.003) and postprandial blood sugar (p=0.049) in prediabetics accompanied by MetS were statistically significant. It was higher than those without MetS. The median Vit-D level of prediabetics without MetS was higher than those with MetS (p=0.049). The median creatinine value of prediabetics without MetS was higher than that of prediabetics with MetS (p=0.049). CONCLUSIONS: Hypertension, dyslipidemia, abdominal obesity, and metabolic obesity increased in the coexistence of prediabetes and MetS. At the same time, the coexistence of prediabetes and MetS was associated with higher systolic blood pressure, postprandial blood sugar, and LDL levels. Prediabetic individuals accompanied by MetS are at greater metabolic risk. © 2024 Verduci Editore s.r.l. All rights reserved.