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    Comparative investigation of the effects of different materials used with a titanium barrier on new bone formation
    (Wiley, 2013) Ezirganli, Seref; Polat, Serkan; Baris, Emre; Tatar, Ilkan; Celik, Hakan Hamdi
    Objectives In this study, we aimed to study the effects on new bone formation of autogenous blood, deproteinized bovine bone graft (DBBG), and biphasic calcium phosphate (BCP) bioceramic graft materials placed under titanium barriers. Material and methods Twenty-four adult male New Zealand white rabbits were used in this study. Two titanium barriers were fixed on each rabbit's calvarium. The study included four groups, one of which was a control group. The experiment groups, autogenous blood, DBBG (Bio-Oss (R); Geistlich Biomaterials, Wolhusen, Switzerland) and BCP (4BoneTM; Biomatlante, Vigneux de Bretagne, France) were placed under titanium barriers; in the control group, no materials were used. Half of the animals were sacrificed after 1month, and the rest were sacrificed after 3months. After this, micro-computerized tomography images were taken, and a histomorphometric evaluation was carried out. Results The amounts of new bone formation were found to be higher at the third month than at the first month. The differences between the groups were examined with both a micro-computerized tomography and histomorphometric analysis, and no statistical significance was noted in the first month. In contrast, the increase in the amount of new bone formation at the third month was found to be statistically significant only between the DBBG and control groups (P<0.05). Conclusion Autogenous blood with titanium barriers in guided bone regeneration seems to be as successful as DBBG and BCP bioceramic graft material.
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    Neoplasms of the salivary glands in a Turkish adult population
    (Medicina Oral S L, 2010) Kara, Muhammed Isa; Goze, Fahrettin; Ezirganli, Seref; Polat, Serkan; Muderris, Suphi; Elagoz, Sahende
    Objective: This retrospective study aimed to investigate the types and distribution of neoplasm of salivary glands in a Turkish population. Study Design: The histological diagnosis records of the Department of Pathology at Cumhuriyet University were reevaluated for 125 patients who were treated for salivary gland tumors from 1987 to 2008. The neoplasms were analyzed for histological diagnosis, age, sex, and site. The histological diagnoses were analyzed according to the 2005 WHO classification. Results: A total of 125 primary salivary gland neoplasms, consisting of 95 (76%) benign and 30 (24%) malignant groups were recorded. The most common major and minor salivary gland sites were the parotid (61.6%) and palatal glands (9.6%), respectively. Pleomorphic adenoma was the most frequent benign tumor followed by Warthin's tumor. Among the malignant group, adenoid cystic carcinoma was the most prevalent. Age for all cases ranged from 16-80 years; mean age was 41.97 years, with a female to male ratio of 1:1.15. Conclusions: Although there were some discrepancies, the characteristics of salivary gland tumors of Turkish patients are in line with those of patients from other countries according to tumor type, tumor site distribution, and age and sex of patients.
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    The Prevalence of Impacted Premolars in the Anatolian Population
    (Aves, 2013) Ezirganli, Seref; Kirtay, Mustafa; Ozer, Koray; Un, Emin Celalettin; Kosger, Hasan Huseyin; Kazancioglu, Hakki Oguz
    Objective: The aim of this study was to determine the prevalence of impacted premolars and the associated pathology of these teeth in the Anatolian population. Methods: This retrospective cohort study was composed of 10246 panoramic radiographs of patients (6074 females, 4172 males) between 2000 and 2011. We reviewed the panoramic radiographs and clinical data and determined the prevalence of impacted premolars to be associated with sex, age, and number of premolars. We investigated the associated pathology and approach of treatment. Results: A total of 83 patients (43 females, 40 males; mean age 23.42 +/- 11.18 years, range 12 to 69) had 101 impacted permanent premolars that were either mesioangular (n=47, 46.54%), vertical (n=32, 31.68% 9), distoangular (n=14, 13.86%), horizontal (n=6, 5.94%), and/ or buccolingual (n=2, 1.98%). Premolar transmigration was absent. Of these premolars, 7 (6.93%) were associated with cystic lesions. In this study, 61.39% of impacted premolars were extracted; 39 (38.61%) were followed up. Conclusion: The prevalence of impacted premolars in the Anatolian population was determined to be 0.98%. Although premolar impaction is infrequent, early diagnosis is important because most of the cases (93.07%) are asymptomatic.