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    Induces of periodontitis increases salivary orosomucoid levels
    (2018) Gokmenoglu, Ceren; Ongoz Dede, Figen; Sahin, Ismail Onur
    Aim: Periodontitis is characterized by chronic infection and inflammation in periodontal tissues leading to destruction of dental support tissues. Acute-phase proteins are effective markers for the identification and evaluation of inflammatory diseases including periodontitis. Orosomucoid (ORM) is an acute-phase plasma protein, also called alpha-1-acid glycoprotein, which is inflammation sensitive. The aim of this study was to evaluate and compare the salivary levels of ORM and C-reactive protein (CRP) in individuals with/withoutperiodontal disease. Material and Methods: A total of 90 subjects were divided into two groups of 45 patients each; periodontally healthy and chronic periodontitis. Saliva samples were collected, and clinical periodontal parameters and salivary flow rates were evaluated at baseline. The ORM and CRP levels in the saliva were analyzed with enzyme-linked immunosorbent assay. Results: The periodontal clinical parameters were significantly higher in the chronic periodontitis group when compared to those of the healthy controls (P<0.05). There was no significant difference in the salivary flow rate between the chronic periodontitis and periodontally healthy groups (P>0.05). However, the CRP and ORM levels in the saliva were significantly higher in the chronic periodontitis patients than in the healthy controls (P<0.05). In addition, a significant positive correlation was found between the CRP and ORM levels in saliva of all groups (P<0.05). Conclusions: This study revealed that presence of periodontitis was associated with higher salivary CRP and ORM levels. Moreover, the ORM level seemed to be associated with tissue destruction in inflammatory periodontal disease.
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    The Level of Knowledge of Hepatitis B Infection Among Turkish Dental Students
    (2017) Gokmenoglu, Ceren; Sadik, Elif; Altun, Gokcen; Kara, Cankat
    Aim: Dentists are at high risk of hepatitis B infection. The aim of this study was to evaluate the knowledge of students from Ordu univeriyt, faculty of dentistry on hepatitis Materials and Methods:Questionnaires consisting of 76 questions related to students’ socio-demographic status, knowledge of hepatitis infection about the ways of transmission, prevention and risk groups, and vaccination status were distributed to all dental students. Results: Total of 155 students participated in the study and completed the questionairre. The level of knowledge of the 4th and 5th year students was significantly higher than the other students (p=0.001). Fifth year students had significantly better knowledge about the transmission and prevention ways of the hepatitis when compared with the 1st year students B (p=0.001). Although, only 60% percent of the students have been vaccinated, the vaccination rates were higher in both 4th and 5th year-students when compared to the other classes. Fourty-one percent of the students did not know that HBV is contagious during asymptomatic period. Conclusion: There was a lack of knowledge about the hepatitis B infection especially among the 1st and 2nd year students. Therefore, the continuous education of infectious diseases is required starting from the first year of the dental school.
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    Periodontal Health Status of Children with Type 1 Diabetes Mellitus
    (2017) Gokmenoglu, Ceren; Canigur Bavbek, Nehir; Gurel, Mugem Asli; Dincer, Mufide
    Aim: Type 1 diabetes mellitus (DM1) is the most common chronic disease in children and adolescents. The purpose of this study was to determine the relationship between Type 1 diabetes mellitus and periodontal health and also the effect of metabolic control level on both periodontal and dental health.