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    Assessment of Liver Fibrosis with Diffusion-Weighted Magnetic Resonance Imaging Using Different b-values in Chronic Viral Hepatitis
    (Karger, 2015) Kocakoc, Ercan; Bakan, Ayse Ahsen; Poyrazoglu, Orhan Kursat; Dagli, Adile Ferda; Gul, Yeliz; Cicekci, Mehtap; Bahcecioglu, Ibrahim Halil
    Objective: To examine the effectiveness of apparent diffusion coefficient (ADC) values and to compare the reliability of different b-values in detecting and identifying significant liver fibrosis. Subjects and Methods: There were 44 patients with chronic viral hepatitis (CVH) in the study group and 30 healthy participants in the control group. Diffusion-weighted magnetic resonance imaging (DWI) was performed before the liver biopsy in patients with CVH. The values of ADC were measured with 3 different b-values (100, 600, 1,000 s/mm(2)). In addition, liver fibrosis was classified using the modified Ishak scoring system. Liver fibrosis stages and ADC values were compared using areas under the receiver-operating characteristic (ROC) curve. Results: The study group's mean ADC value was not statistically significantly different from the control group's mean ADC value at b = 100 s/mm(2) (3.69 +/- 0.5 x 10(-3) vs. 3.7 +/- 0.3 x 10(-3) mm(2)/s) and b = 600 s/mm(2) (2.40 +/- 0.3 x 10(-3) vs. 2.5 +/- 0.5 x 10(-3) mm(2)/s). However, the study group's mean ADC value (0.99 +/- 0.3 x 10(-3) mm(2)/s) was significantly lower than that of the control group (1.2 +/- 0.1 x 10(-3) mm(2)/s) at b = 1,000 s/mm(2). With b = 1,000 s/mm(2) and the cutoff ADC value of 0.0011 mm(2)/s for the diagnosis of liver fibrosis, the mean area under the ROC curve was 0.702 +/- 0.07 (p = 0.0015). For b = 1,000 s/mm(2) and the cutoff ADC value of 0.0011 mm(2)/s to diagnose significant liver fibrosis (Ishak score = 3), the mean area under the ROC curve was 0.759 +/- 0.07 (p = 0.0001). Conclusion: Measurement of ADC values by DWI was effective in detecting liver fibrosis and accurately identifying significant liver fibrosis when a b-value of 1,000 s/mm(2) was used. (C) 2015 S. Karger AG, Basel
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    Foreign body aspiration in children
    (2020) Gul, Evrim; Cakmak, Muharrem; Gul, Yeliz; Gurger, Mehtap; Sari, Mehmet Yusuf; Atescelik, Metin
    Aim: Foreign body aspiration (FBA) is a life-threatening conditional. We aimed to share the results of FBA in children.Material and Methods: We evaluated retrospectively files of 61 patients between the ages 1-10 underwent rigid broncoscopy. It were evaluated the types and anatomic localization of aspirated foreign bodies, the age distribution of children, treatment procedures. The results was assessed by Chi-square test or Fisher's exact test. P0.05 was considered significant.Results: The mean ages were 3.29±1.91. 62% of the patients were male, and 38% were female (p0.05). Aspirated foreign body localized right in 38 patients, left in 13 patients, tracheal in 6 patients. Foreign body was observed in the right main bronch in 18 patients, in the right lower lobe bronch in 19 patients, in the medium lobe bronch in 1 patients, in the left main bronch in 9 patients, in the left lower bronchus in 4 patients. Bronchoscopies were negative in four patients, although foreign body aspiration is considered.Conclusion: FBAs are common in children. In children younger than 3 years are more common. The gold standard in treatment is rigid bronchoscopy. The incidence and severity of airway FBA can be reduced by parental education and public awareness.
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    The role of apparent diffusion coefficient values in differentiation between adrenal masses
    (Elsevier Science Inc, 2014) Cicekci, Mehtap; Onur, Mehmet Ruhi; Aydin, Ayse Murat; Gul, Yeliz; Ozkan, Yusuf; Akpolat, Nusret; Kocakoc, Ercan
    The aim of this study was to evaluate the utility of apparent diffusion coefficient (ADC) values in differentiation between solid adrenal masses. The ADC values of 73 adrenal lesions (54 benign, 19 malignant) in 69 patients were measured at b 100, 600 and 1000 gradients on diffusion-weighted magnetic resonance imaging (DW-MRI). No statistically significant difference was found between ADC values of benign and malignant adrenal masses, nonadenomatous benign adrenal masses and malignant adrenal masses, adrenal adenomas and nonadenomatous lesions, adenomas and metastases, adenomas and pheochromocytomas, metastases and pheochromocytomas. ADC values are not helpful in the differentiation between solid adrenal masses. (C) 2014 Elsevier Inc. All rights reserved.