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  • Küçük Resim
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    The association between neutrophil to lymphocyte ratio and contrast induced nephropathy in patients with ST segment elevation myocardial infarction
    (2019) Gulcu, Oktay
    Aim: The increase in the number of percutaneous coronary interventions(PCI) has also led to an increase in risk associated with intervention-including radiation injury, contrast-induced nephropathy (CIN), risk of stroke, and vascular complications. The development of CIN is an important clinical situation in patients undergoing PCI. In this study we aimed to investigate the association between inflammatory parameters and CIN development in patients with ST segment elevation myocardial infarction (STEMI).Material and Methods: Patients who underwent coronary angiography with STEMI diagnosis between January 2015 and March 2018 were included in the study. Two groups were formed according to the CIN status and predictors of CIN were investigated. Results: The average age of the patients is 58±12 years and 78.2% males. In multivariate analysis, NLR (OR: 0.92, 95% CI: 0.86-0.98 and p: 0,022) and Lesion length (OR: 0.88, 95% CI: 0.79-0.98 and p: 0,029)and were associated with CIN development. Conclusions: In this study, we showed that lesion length and NLR were independent predictors of CIN and we proposed that inflammatory process could play key role in CIN development when compared to traditional risk factors. Keywords: Neutrophil to lymphocyte ratio; coronary artery disease; contrast-induced nephropathy; propensity score matching.
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    Elevated serum uric acid levels are associated with increased risk score and MACE development in patients with STEMI
    (2019) Aksu, Ugur; Gulcu, Oktay
    Aim: Although the relationship between changes in serum uric acid (UA) levels and adverse events in ST segment elevation myocardial infarction (STEMI) patients is well known, the effect of an increase in UA levels on risk scores or major adverse cardiovascular event (MACE) development are not well established. In this study, we investigated the effects of ordinal changes in serum UA levels on adverse events and risk scores in STEMI patients. Material and Methods: The patients presenting with a diagnosis of STEMI and undergoing coronary angiography were included in the study. The patients were divided into seven groups evenly according to baseline UA levels and the effects of changes in UA levels on risk score and MACE were investigated. Results: A total 1200 STEMI patients was included in the study. The mean age of the patients was 62 years and 72% of them were males. While both Syntax score-II (SS-2) and Cadillac scores (CS) were lower among Group-1 and Group-4; SS-2, CS and development of MACE were markedly increased with an increase in UA levels. Conclusions: The UA levels in STEMI patients can be guiding for the clinician regarding the development of adverse event and patient-based intensive approaches should be considered in the patients with higher UA levels.
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    Evaluation of the relationship between coronary slow flow phenomenon and serum magnesium levels
    (2021) Ozturk, Mustafa; Turan, Oguzhan; Ceyhun, Gokhan; Aksakal, Emrah; Karaman, Kayihan; Gulcu, Oktay; Demirelli, Selami; Korkmaz, Ali Fuat
    Aim: Splint use is often recommended following wrist injection patients diagnosed with carpal tunnel syndrome (CTS), but there is not any data in the literature pertaining to the impact of splint treatment, used before injection, on the results of local injection treatment. The aim of this study to evaluate whether or not splint use starting before the injection would impact the local injection treatment outcomes.Materials and methods: Fifty seven patients (57 hands) with CTS and underwent ultrasound-guided injection were included in the study, and patients were divided into two groups in terms of splint use. Median nerve cross-sectional area (MNCSA), pain/numbness by visual analogue scale (VAS), symptoms and functionality by Boston Carpal Tunnel Questionnaire (BCTQ) were investigated before injection and 15 days after injection.Results: There was significant change over time in MNCSA, VAS, and BTCQ scores in groups. The patients not using splint group had significantly higher percentage change in VAS nighttime score.Conclusion: Our findings has shown that using neutral wrist splint, starting before and continuing after injection treatment, did not increase the injection treatment efficacy and may actually have negative effect on improvement in VAS nighttime scores.