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Öğe Foreign body aspiration in children(2020) Gul, Evrim; Cakmak, Muharrem; Gul, Yeliz; Gurger, Mehtap; Sari, Mehmet Yusuf; Atescelik, MetinAim: Foreign body aspiration (FBA) is a life-threatening conditional. We aimed to share the results of FBA in children.Material and Methods: We evaluated retrospectively files of 61 patients between the ages 1-10 underwent rigid broncoscopy. It were evaluated the types and anatomic localization of aspirated foreign bodies, the age distribution of children, treatment procedures. The results was assessed by Chi-square test or Fisher's exact test. P0.05 was considered significant.Results: The mean ages were 3.29±1.91. 62% of the patients were male, and 38% were female (p0.05). Aspirated foreign body localized right in 38 patients, left in 13 patients, tracheal in 6 patients. Foreign body was observed in the right main bronch in 18 patients, in the right lower lobe bronch in 19 patients, in the medium lobe bronch in 1 patients, in the left main bronch in 9 patients, in the left lower bronchus in 4 patients. Bronchoscopies were negative in four patients, although foreign body aspiration is considered.Conclusion: FBAs are common in children. In children younger than 3 years are more common. The gold standard in treatment is rigid bronchoscopy. The incidence and severity of airway FBA can be reduced by parental education and public awareness.Öğe Meteorologic parameters and migraine headache: ED study(W B Saunders Co-Elsevier Inc, 2015) Yilmaz, Mustafa; Gurger, Mehtap; Atescelik, Metin; Yildiz, Mustafa; Gurbuz, SukruAim: Migraine is common in society and is one of the primary causes of chronic headache with episodes. In this study, we aimed to determine the role of meteorologic parameters and moon phase on triggering migraine attacks and effects on the number of patients presenting to the emergency department with migraine headaches. Materials and Methods: Patients admitted to the emergency department due to a migraine headache during a 1-year period were studied retrospectively. Correlation between moon phases, pressure, temperature, humidity, wind speed values of meteorologic observation, and recording station located in the same city and daily number of patients was analyzed. Results: A total of 3491 patients, of whom 72% (n = 2518) were women, were enrolled. The average daily number of patients was 9.6 +/- 4 (3-24). A statistically significant correlation was found between the number of daily patients and daily maximum temperature (P = .005), mean temperature (P = .013), minimum temperature (P = .041), and daily temperature change (P = .003). In addition, a negative correlation was found between the daily number of patients presenting to the emergency department and daily relative humidity (in percentage; P = .031). No significant relationship was found between moon phases and the number of patients. Conclusion: We have determined that the number of patients admitted to the emergency department with migraine headache has increased with high temperature and low humidity and that there is no relationship between the number of patients and moon phases. (C) 2014 Elsevier Inc. All rights reserved.Öğe Paraoxonase-1 gene in patients with chronic obstructive pulmonary disease investigation Q192R and L55M polymorphisms(Zhejiang Univ Sch Medicine, 2015) Gurbuz, Sukru; Yildiz, Mustafa; Kara, Murat; Kargun, Kursat; Gurger, Mehtap; Atescelik, Metin; Alatas, Omer DoganBACKGROUND: The effect of increased oxidative stress on the development of chronic obstructive pulmonary disease (COPD) is well known. One of the antioxidative systems against oxidative stress in human body is paraoxonase (PON) enzyme that protects low density lipoproteins (LDL) against oxidation. This study aimed to explore the polymorphisms on PON1, Q192R, L55M genes of patients with COPD. METHODS: DNAs extraction was obtained from blood samples of 50 patients diagnosed with COPD and 50 patients as a control group who were presented to emergency clinic. Genotypes were obtained with polymerase chain reaction (PCR) and AIw I and Hsp92II restriction enzymes were used for Q192R and L55M polymorphisms, respectively. Analysis of data was done with the Chi-square test and Fisher's exact test. RESULTS: A statistically significant difference in Q192R polymorphism was found between the COPD patients and the control group (P=0.05). There was no statistically significant difference in L55M polymorphisms between the patient and control groups (P>0.05). Q192R polymorphism was significantly correlated with the PON1 gene and cigarette smoking; however other risk factors did not show any significant correlation with this polymorphism. Though L55M polymorphism was significantly correlated with family history and tuberculosis, there was no significant correlation with other risk factors. CONCLUSION: We believe that more studies are needed to study the correlation of L55M polymorphism with other factors.