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    The correlation between delirium subtypes and treatment efficacy and biochemical parameters: A preliminary study
    (2019) Gurok, Mehmet Gurkan; Kazgan, Asli; Kaya, Mehmet Onur; Atmaca, Murad
    Aim: Delirium is one of the most important emergency cases in geriatric patient population with high morbidity and mortality rates. In clinical practice, three delirium types are defined as hyperactive, hypoactive and mixed according to the psychomotor activity and the level of wakefulness. In the present study, the purpose was to examine the treatment response of the subtypes of delirium and its relation with possible biochemical parameters.Material and Methods: Thirty patients, who were diagnosed with delirium and who were hospitalized for treatment were included in the present study. Following the classification of the patients according to the subtypes of delirium, they were evaluated before the treatment and on the 7th day of the treatment. In both interviews, the Delirium Rating Scale (DRS), Richmond Agitation and Sedation Scale (RASS), and Memorial Delirium Rating Scale (MDRS) were applied to the patients. In addition, the biochemical parameters that were required for the patients in relevant clinics were recorded.Results: Delirium patients consisted of a total of 30 patients. The patients of all three subtypes of delirium responded to the treatment scores at significant levels in terms of scale scores. However, when the Hyperactive, Hypoactive and Mixed subtypes were evaluated in terms of the difference of change on the 1st and 7th days of the treatment separately, it was determined that the difference of change values were significantly higher in the hyperactive type in terms of RASS, DRS and MDRS (p=0.004; p=0.002; p=0.001, respectively). Conclusions: As a result, the findings of the present study showed that patients who are diagnosed with delirium might show different treatment responses according to motor subtypes. Further studies are required to be conducted with bigger sampling groups.Keywords: Delirium; treatment efficacy; biochemical parameters.
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    Distress tolerance levels in alopecia areata patients
    (2021) Gurok, Mehmet Gurkan; Gocer Gurok, Nese
    Aim: Alopecia areata (AA) is a clinical manifestation that is characterized with hair loss with hairs in sharp borders, and in a round or oval shape on the scalp or in any part of the body. It is considered that genetic factors, infections, autoimmune factors, neuropeptides and psychological factors play roles in its etiopathogenesis. As psychological traumas have an important role in the onset and exacerbation period of the disease, it is also considered as a psychosomatic one. Distress Tolerance (DT) is defined as the capacity to experience and survive negative psychological situations. DT is considered important in etiopathogenesis of diseases, and it is also considered as one of the factors that determine the response to treatment and is targeted to increase in psychotherapy. In the present study, the purpose was to determine the Distress Tolerance levels of AA patients, and compare them with healthy controls. Material and Methods: A total of 36 patients, who applied to the dermatology clinic, and who did not have any other diseases except AA, were included in the study. In the Control Group, 36 healthy volunteers, who were matched in terms of age and gender with the Patient Group, and who did not have any physical or mental illness, were included. The Sociodemographic and Clinical Data Form (SCDF), Distress Tolerance Scale (DTS), and Hospital Anxiety and Depression Scale (HADS) were given to the Patient and Control Group. Results: No significant differences were detected between the groups in terms of age and gender. A significant difference was detected in the Patient Group in terms of both the total score of DTS (p<0.001) and the DTS tolerance, DTS regulation and DTS selfefficacy subscales (p=0.004, p=0.008, p=0.006, respectively). When the groups were analyzed in terms of HADS results, the anxiety levels were higher at a significant level in the Patient Group (p<0.001), and no significant differences were detected in terms of depression scores (p=0.57). Conclusions: In this study, the DT levels were determined as low in AA patients. The DT levels in AA, which is also considered as a psychosomatic disease, might be important for the onset, course and treatment of the disease. Meanwhile, it may also be aimed to increase the DT levels during the psychotherapy process.