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    Evaluation of changes in neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in patients with vitiligo
    (2019) Sarac, Gulbahar; Altunisik, Nihal; Sener, Serpil; Hakverdi, Gulden
    Aim: Vitiligo is an acquired disease with loss of melanocytes, etiology of which is unclear. The aim of this study is to determine the role of systemic inflammation in vitiligo by measuring the Neutrophil-Lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) markers included in routine hemogram test, in patients with vitiligo.Material and Methods: The study was carried out by reviewing the data of patients who applied to İnönü University Faculty of Medicine Dermatology Polyclinic and diagnosed with vitiligo after Wood’s lamp examination, between July 2012 and February 2018. The study was performed retrospectively by reviewing patient files and ethics committee approval was not obtained.Results: A total of 170 individuals including 79 vitiligo patients and 91 healthy individuals were included in the study. When the vitiligo patients and healthy control group were compared in terms of routine hemogram parameters, statistically significant differences were found in terms of erythrocyte distribution width (RDW), but there were no statistically significant differences in terms of NLR, PLR, lymphocyte, neutrophil, platelets and White bloodcell (WBC) counts.Conclusion: In our study, only RDW value was found to be higher in patients with vitiligo compared to healthy controls, and no difference was found in other parameters indicating systemic inflammation.
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    Evaluation of Patients with Cutaneous Leishmaniasis Who Admitted to Dermatology Clinic in Kahramanmaras Sutcu Imam University Medical Faculty
    (Duzce Univ, 2017) Sener, Serpil; Karaman, Ulku; Hakverdi, Gulden; Sarac, Gulbahar; Tetik, Burcu Kayhan
    Objective: Leishmaniasis is a group of diseases, in different clinical forms, caused by the intracellular protozoan parasites, Leishmania species. The disease is transmitted by a female sand fly infected with the parasite sucking blood from people. Leishmania species causes three main clinical forms: cutaneous, mucocutaneous, and visceral disease. The clinical forms may vary by species and/or region of acquisition. Two forms are observed in Turkey; visceral leishmaniasis and cutaneous leishmaniasis. The aim of this study is to examine the status of Cutaneous Leismaniasis(CL) in the Kahramanmaras province and contribute to the prevention of the disease in this region. Methods: 20 CL cases were reported officially in 2009. CL was diagnosed by skin biopsy or smear. Intralesional meglumine antimoniate was applied for patients treatment. Results: Out of 20 cases, 12 and 8 were female and male. According to smear and biopsy, was found positive in 13 cases, and negative in 7 cases and the results of biyopsy was assessment as CL. Conclusion: By defining the status of CL in the region, the study can be considered to contribute to the planning of methods of intervention, public health education and personal preventative precautions.