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    Effects of aflatoxin B1 on weight of total body and different organs in rabbits
    (1996) Hanifi Emre M.
    Bin this study, we used 30 male New Zeland rabbits strain (Oryctolagus cuniculus huxleyi). The rabbits were groupped as A. B. C groups and given 0.005, 0.0075 and 0.0010 mg/kg/every other day respetively. None of istatistically differences found between groups according to weight of total body, right suprarenal gland, left and right kidney, heart, stomach, and salivary glands. On the other hand it was determined istatistically differences between groups' weight of left suprarenal and lung. Data were compared and discussed with literature. © TÜBITAK.
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    Investigation of propolis’ effect on thiobarbituric acid reactive substances and anti-oxidant enzyme levels of hippocampus in diabetic rats induced by streptozotocin
    (2015) Köksal B.; Hanifi Emre M.; Polat A.
    BACKGROUND: Propolis is an organic resinous viscous substance collected from flower bud and plant sprig by bees. Propolis has a potential treatment agent for oxidative damage caused by diabetes in hippocampus due to its flavonoid and phenolic content. AIM: In this study effect of propolis on thiobarbituric acid reactive substances and anti-oxidative enzyme levels of hippocampus in diabetic rats induced by streptozotocin was investigated. MATERIALS AND METHODS: The study involved measuring levels of SOD, CAT, GSH-Px and TBARs in hippocampus tissue of STZ-induced diabetic rats (Adult Male Sprague Dawley rats) after applying propolis for one month. The subjects of the study were composed of 51 rats randomly assigned to four groups (Control, STZ, P+STZ and STZ+P). For analysis of data, Kruskal Wallis Test was utilized. RESULTS: The findings of the study showed that there were no significant difference in the levels of TBARS, SOD, CAT and GSH-Px of hippocampus across the groups. CONCLUSION: Propolis application in four-week duration does not have effect on TBARS, SOD, CAT and GSH-Px levels of hippocampus of diabetic rats. These findings mean that more time for observing oxidative harms on hippocampus is needed. © 2015 Burcu Köksal, Memet Hanifi Emre, Alaadin Polat.