Yazar "Isik B." seçeneğine göre listele
Listeleniyor 1 - 5 / 5
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Cost-effective therapies for HCC: Resection and ablation(Springer International Publishing, 2021) Ersan V.; Isik B.Liver transplantation is the most effective option for the treatment of both HCC and underlying chronic liver disease. The stage of the disease, liver function, tumor biology, and concomitant diseases are determinant in the treatment approach. In addition to these, the capacity of the center, the experience of doctors in liver disease treatment, the economic share allocated to the health system, and equipment and trained personnel play an important role in determining the treatment. Surgical resection and some of the local ablative treatments such as PEI, RFA, and MWA can provide comparable results to liver transplantation at a lower cost in selected patients. On the other hand, the cost of the procedures is not standard, with many variables, and reveals differences between social security coverage of the countries. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2021. All rights reserved.Öğe Enhanced role of multipair donor swaps in response to size incompatibility: The first two 5-way and the first 6-way liver paired exchanges(Elsevier B.V., 2024) Yilmaz S.; Sönmez T.; Ünver M.U.; Ince V.; Akbulut S.; Sarici K.B.; Isik B.A significant portion of liver transplantations in many countries is conducted via living-donor liver transplantation (LDLT). However, numerous potential donors are unable to donate to their intended recipients due to factors such as blood type incompatibility or size incompatibility. Despite this, an incompatible donor for one recipient may still be a viable donor for another patient. In recent decades, several transplant centers have introduced liver paired exchange (LPE) programs, facilitating donor exchanges between patients and their incompatible donors, thereby enabling compatible transplants. Initially, LPE programs in Asia primarily involved ABO-i pairs, resulting in 2-way exchanges mainly between blood type A and B recipients and donors. This practice has led to a modest 1% to 2% increase in LDLTs at some centers. Incorporating size incompatibility alongside blood type incompatibility further enhances the efficacy and significance of multiple-pair LPEs. Launched in July 2022, a single-center LPE program established at Inonu University Liver Transplant Institute in Malatya, Türkiye, has conducted thirteen 2-way, nine 3-way, four 4-way, two 5-way, and one 6-way LPEs until February 2024. In 2023 alone, this program facilitated 64 LDLTs, constituting 27.7% of the total 231 LDLTs performed. This paper presents the world's first two 5-way LPEs and the first 6-way LPE. © 2024 The AuthorsÖğe Gastric perforation during chest tube placement for acute diaphragmatic rupture and review of the literature(Elsevier BV, 2006) Yilmaz M.; Isik B.; Ara C.; Yilmaz S.; Kutlu R.; Kocak O.; Ugras M.[No abstract available]Öğe Individual patient assessment and therapy decision-making in a live donor-based liver transplant institute(Springer International Publishing, 2021) Carr B.I.; Yilmaz S.; Isik B.; Kutlu R.Patients with HCC present with both their tumor and underlying liver disease, requiring input from several disciplines for optimal therapeutic decision-making. We describe our method, which emphasizes the importance of a multidisciplinary approach and a tumor board. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2021. All rights reserved.Öğe Portosystemic shunt surgery in patients with idiopathic noncirrhotic portal hypertension(Medical Science International, 2016) Karagul S.; Yagci M.A.; Tardu A.; Ertugrul I.; Kirmizi S.; Sumer F.; Isik B.Background: Idiopathic noncirrhotic portal hypertension (INCPH) is a rare disease characterized by increased portal venous pressure in the absence of cirrhosis and other causes of liver diseases. The aim of the present study was to present our results in using portosystemic shunt surgery in patients with INCPH. Material/Methods: Patients who had been referred to our Liver Transplantation Institute for liver transplantation and who had undergone surgery from January 2010 to December 2015 were retrospectively analyzed. Patients with INCPH who had undergone portosystemic shunt procedure were included in the study. Age, sex, symptoms and findings, type of portosystemic shunt, and postoperative complications were assessed. Results: A total of 1307 patients underwent liver transplantation from January 2010 to December 2015. Eleven patients with INCPH who did not require liver transplantation were successfully operated on with a portosystemic shunt procedure. The mean follow-up was 30.1±19 months (range 7–69 months). There was no mortality in the perioperative period or during the follow-up. Two patients underwent surgery again due to intra-abdominal hemorrhage; one had bleeding from the surgical site except the portacaval anastomosis and the other had bleeding from the h-graft anastomosis. No patient developed encephalopathy and no patient presented with esophageal variceal bleeding after portosystemic shunt surgery. Shunt thrombosis occurred in 1 patient (9.9%). Only 1 patient developed ascites, which was controlled medically. Conclusions: Portosystemic shunt surgery is a safe and effective procedure for the treatment of patients with INCPH. © Ann Transplant, 2016.
