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Öğe Assessment of quantitative zonal parameters of prostate gland in discrimination of normal, benign, and malignant conditions: are these the more reliable parameters in the diagnosis of prostate cancer?(Verduci Publisher, 2023) Karaca, L.; Ozdemir, Z. M.; Kahraman, A.; Celik, H.; Kaya, S.OBJECTIVE: Prostate cancer diagnosis and treatment are increasing in current public healthcare programs. An improved resolution multiparametric magnetic resonance imaging (MRI) has shown the potential to enhance the detection and differentiation of this medical condition. In this study, MR perfusion parameters were investigated in different ages and diseases to differentiate clinically significant prostate cancer.PATIENTS AND METHODS: From January 2017 to December 2022, 72 consecutive patients, who had undergone multiparametric MR imaging were enrolled in this study. Four different patient groups were formed: (1) those with prostate cancer, (2) those with prostatitis, (3) those with benign prostate hyperplasia (BPH), and (4) a control group. Quantitative dynamic contrast-enhanced (DCE)-MRI pharmacokinetic parameters included Ktrans, Kep, Ve, and iAUG. Different measurements were obtained from both the peripheral and transitional zones (PZ and TZ, respectively). Means values were compared between groups based on a univariate analysis.RESULTS: Ktrans and Kep values in the PZ were found to be statistically significantly lower in the control group (p = 0. 003 and p = 0. 011, respectively). It was seen that Ktrans and Ve measurements obtained from PZ had a statistically significant determinant in detecting malignancy (p = 0. 013 and p = 0. 036, respectively). It was seen that Ktrans, Ve, and iAUG obtained from the TZ showed a statistically significant difference in prostate cancer (p = 0.025, p = 0.005, and p = 0. 011, respectively) in contrast to other cases. Peripheral Ve values were statistically significantly lower than those measured Ve values from the TZ in prostate cancer cases (p = 0.002) in contrast to the other cases.CONCLUSIONS: Quantitative DCE-MRI parameters may vary according to age, disease, and zonal anatomy. These differences may contribute to the diagnosis of clinically relevant prostate cancer.Öğe Computed tomographic perfusion imaging for the prediction of response transarterial radioembolization with Yttrium-90 glass microspheres of hepatocellular carcinoma (vol 25, pg 366, 2021)(Verduci Publisher, 2021) Kaplan, E.; Kutlu, R.; Erbay, M. F.; Kahraman, A.; Kekilli, E.; Karadag, M. Otlu; Kaplan, S.[Abstract Not Available]Öğe Endometrial carcinoma detection with 3.0 Tesla imaging: which sequence is more useful(Verduci Publisher, 2022) Karaca, L.; Ozdemir, Z. M.; Kahraman, A.; Yilmaz, E.; Akatl, A.; Kural, H.OBJECTIVE: Detection of endometrial cancer (EC) is crucial in pre-operative EC management. The study aimed at determining the most reliable sequence in magnetic resonance imaging (MRI) evaluation at the EC. Different sequences were compared using histopathological results as the gold standard. PATIENTS AND METHODS: In this retrospective study, 62 women diagnosed with EC were examined using 3 Tesla MR and post-hysterectomy histopathological examination. The MRI protocol included diffusion- weighted imaging (DWI), T2 weighted images, Dynamic Contrast T1 weighted images, and ZOOMit DWI. Apparent diffusion coefficient (ADC) maps were also obtained. ADC maps were calculated for both DWI and ZOOMit DWI. All serial images were analyzed by endometrial distance to account for myometrial invasion and tumor size. All sequences and histopathological results were compared using the paired sample t-test. RESULTS: In all 32 women, post-hysterectomy histopathological confirmation was obtained. Mean myometrial invasion values were not significantly different after comparing DWI, ZOOM it DWI, and Dynamic contrast enhancement (DCE)-T1WI (p=0.054, p=0.039). The first strong correlation was found between DWI and ZOOMit DWI (0.943). The second was between ZOOMit DWI and DCE-T1 WI (0.949). Comparing each set of sequences, no statistically significant differences in tumor size ( p > 0.05) were found. Also, no statistically significant differences between images and histopathological size were found. The ADC values of ZOOMit DWI indicated that this method detected significant differences between EC histological subtypes. CONCLUSIONS: Each sequence is essential and valuable, whereas priorities may vary depending on the desired information. The most valuable sequences for the myometrial invasion were ZOOMit and conventional DWI. T2WI and DCE T1 WI were more valuable sequences the size of EC.Öğe Evaluation of aqueduct CSF flow dynamics with cine phase contrast MRI in patients with idiopathic intracranial hypertension(Wiley-Blackwell, 2014) Akay, R.; Kamisli, O.; Kahraman, A.; Oner, S.; Ozcan, C.[Abstract Not Available]Öğe Evaluation of aqueductal CSF flow dynamics with phase contrast cine MR imaging in idiopathic intracranial hypertension patients: preliminary results(Verduci Publisher, 2015) Akay, R.; Kamisli, O.; Kahraman, A.; Oner, S.; Tecellioglu, M.OBJECTIVE: We aimed to evaluate dynamic cerebrospinal fluid (CSF) flow in idiopathic intracranial hypertension (IIH) patients with new MRI technology phase contrast cine (PCC) MRI. PATIENTS AND METHODS: Nineteen patients diagnosed with idiopathic intracranial hypertension and 11 healthy volunteers were included in this study. Nine of the IIH cases had been previously diagnosed and had been on drug treatment and 10 cases were diagnosed with IIH recently and had not been put on drug treatment yet. All CSF flow datas were evaluated by phase contrast-MRI using a 1,5 T MRI. The CSF flow was calculated in the equidistant MRI sequence which was taken through a cardiac cycle. RESULTS: Mean aqueduct area in the IIH group was 3.04 +/- 1.14 mm(2), mean peak rate was 3.29 +/- 1.77 cm/sec, mean average rate was 0.35 +/- 0.33 cm/sec and mean flow was 0.67 +/- 0.95 ml/min. In the control group mean aqueduct area was 2.87 +/- 1.01 mm(2), mean peak rate was 4.20 +/- 1.40 cm/sec, mean average rate was 0.37 +/- 0.18 cm/sec and mean flow was 0.64 +/- 0.40 ml/min. A statistically significant difference was found for the PCC MRI parameter of mean rate value (p: 0.007) between the control group and IIH patients. A statistically insignificant (p: 0.058) but marked difference was found for mean flow value. CONCLUSIONS: To our knowledge this study is the first CSF flow study in the idiopathic intracranial hypertension patients. We found a difference between the IIH groups and controls in mean rate and flow parameters. It was interesting that the mean rate and flow values of the untreated group that were higher than the controls. CSF flow analysis may be a marker to follow up IIH patients.Öğe Varying irrigation rates effect on yield and yield components of chickpea(Springer, 2013) Dogan, E.; Kahraman, A.; Bucak, B.; Kirnak, H.; Guldur, M. E.This study was conducted to determine the effect of different supplemental irrigation rates on chickpea grown under semiarid climatic conditions. Chickpea plots were irrigated with drip irrigation system and irrigation rates included the applications of 0 (I (0)) 25 (I (25)), 50 (I (50)), 75 (I (75)), 100 (I (100)), and 125 % (I (125)) of gravimetrically measured soil water deficit. Plant height, 1,000 seed weight, yield, biomass, and harvest index (HI) parameters were determined in addition to yield-water functions, evapotranspiration (ET), water use efficiency (WUE), and irrigation water use efficiency (IWUE). Significant differences were noted for plant height (ranging from 24.0 to 37.5 cm), 1,000 seed weight (ranging from 192.0 to 428.7 g), and aboveground biomass (ranging from 2,722 to 6,083 kg ha(-1)) for water applications of I (0) and I (125). Statistical analysis indicated a strong relationship between the amount of irrigation and yield, which ranged from 256.5 to 1,957.3 kg ha(-1). Harvest index values ranged between 0.092 and 0.325, while WUE and IWUE values ranged between 1.15-4.55 and 1.34-8.36 (kg ha(-1) mm(-1)), respectively.
