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Öğe Assessment of myocardial changes in athletes with native T1 mapping and cardiac functional evaluation using 3 T MRI(The International Journal of Cardiovascular Imaging, 2016) Görmeli, Cemile Ayşe; Görmeli, Gökay; Yağmur, Jülide; Özdemir, Zeynep; Kahraman, Ayşegül; Çolak, Cemil; Özdemir, RamazanIntensive physical exercise leads to increases in left ventricular muscle mass and wall thickness. Cardiac magnetic resonance imaging allows the assessment of functional and morphological changes in an athlete’s heart. In addition, a native T1 mapping technique has been suggested as a non-contrast method to detect myocardial fibrosis. The aim of this study was to show the correlation between athletes’ cardiac modifications and myocardial fibrosis with a native T1 mapping technique. A total of 41 healthy non-athletic control subjects and 46 athletes underwent CMR imaging. After the functional and morphological assessments, native T1 mapping was performed in all subjects using 3.0 T magnetic resonance imaging. Most of the CMR findings were significantly higher in athletes who had C5 years of sports activity when compared with non-athletic controls and athletes who had \5 years of sports activity. Significantly higher results were shown in native T1 values in athletes who had \5 years of sports activity, but there were no significant differences in the left ventricular end-diastolic volume, left ventricular end-diastolic mass, or interventricular septal wall thickness between non-athletic controls and athleteswho had \5 years of sports activity. The native T1 mapping technique has the potential to discriminate myocardial fibrotic changes in athletes when compared to a normal myocardium. The T1 mapping method might be a feasible technique to evaluate athletes because it does not involve contrast, is non-invasive and allows for easy evaluation of myocardial remodeling.Öğe Ekstremite güçsüzlüğünün nadir görülen bir sebebi: von hippel lindau hastalığı ve radyolojik görüntülemenin tanıdaki katkıları(İnönü Üniversitesi Tıp Fakültesi Dergisi, 2015) Görmeli, Cemile Ayşe; Aydın, Zeynep Banu; Görmeli, Gökay; Aydın, Hasan; Dursun, Recep; Kahraman, Ayşegül; Özdemir, Zeynep; Durak, Mehmet AkifVon Hippel Lindau Hastalığı, 3. kromozomun kısa kolundaki hasar nedeniyle oluşan nadir görülen otozomal dominant bir hastalıktır. Von Hippel Lindau Hastalığı'nın prevelansı 1:35000-1:40000 olarak bildirilmiştir. Retinal hemanjiom ve merkezi sinir sistemi hemanjiomları hastalığın ana belirtileri olmakla beraber adrenal feokromasitoma, paraganglioma, böbrek hücre tümörleri, pankreatik kistler, nöroendokrin tümörler ve epididim kistleri daha sonra eşlik edebilir. Bu hastalık fenotipik değişkenlik gösteren multi sistemik bir hastalıktır. Elli yaşında erkek hasta, 2 aydır devam eden sağ üst ve alt ekstremitede güçsüzlük öyküsü ile başvurdu. Manyetik rezonans incelemelerinde serebellar ve spinal hemanjioblastomlar; pankreatik ve renal kistler saptandı. Bu olguda merkezi sinir sisteminde semptomatik hemanjiomları, çoklu renal ve pankreatik kistleri olan Von Hippel Lindau tanısı alan olgunun radyolojik görüntülerini ve klinik seyrini sunmayı amaçladık.Öğe The evaluation of non ischemic dilated cardiomyopathy with T1 mapping and ECV methods using 3T cardiac MRI(La radiologia medica, 2016) Görmeli, Cemile Ayşe; Özdemir, Zeynep; Kahraman, Ayşegül; Yağmur, Jülide; Özdemir, Ramazan; Çolak, CemilAbstract Purpose The aim of this study was to examine the correlation between ventricular function and the extracellular volume fraction (ECV) in patients with non-ischemic dilated cardiomyopathy (NIDCM) using 3.0 T magnetic resonance imaging (MRI). We also hypothesized that native T1 and ECV values would be increased in patients with NIDCM, independent of the left ventricular ejection fraction (LVEF). The findings of our study could lead to further studies of the follow-up protocols. Materials and methods In total, 53 consecutive dilated cardiomyopathy patients who had undergone cardiac MRI were functionally evaluated and underwent tissue characterization. Results The mean native T1 value was 1235 ± 10 ms, and the mean ECV value was 35.4 ± 2.7% in the myocardia. The LVEF values ranged from 29 to 44%. No significant correlations were observed between functional analysis measurements and native T1 or ECV values. Conclusions Our results showed that myocardial fibrosis is unrelated to cardiac functional findings in NIDCM patients. Therefore, we propose that these patients should be evaluated using MRI and tissue characterization techniques, in addition to cardiac functional analysis.Öğe Intraosseous lipoma presenting as a sphenoid sinus mass(Eur Rev Med Pharmacol Sci, 2011) Doğan, Metin; Kahraman, Ayşegül; Fırat, Cemal; Kahraman, Bayram; Karataş, Erkan; Kızılay, Ahmet– Intraosseous lipoma is an uncommon mesenchymal tumor that is frequently found in appendecular skeleton. In extremely rare conditions, it can appear in sphenoid bone, and only 2 cases have been described in literature until now. We present a case of lipoma in the body of the sphenoid bone mimicking sphenoid sinus tumor. A 16-year-old man presented to Department of Otorhinolaryngology with a complaint of nonspecific headache. There were any clinical findings on physical examination. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed and the diagnosis was made on these imaging findings. Other diagnostic technique, invasive histopathological assessment was not necessary. To our knowledge, this is the first case of lipoma in the body of the sphenoid bone with indentation to sphenoid sinus. The patient has been followed-up radiologically without the need for surgery for two years.Öğe KONJENİTAL SEMİNAL VEZİKÜL KİSTİ(2013) Kahraman, Ayşegül; Ediz, Caner; Taşdemir, Cemal; Kahraman, Bayram; Altıntaş, Ramazan; Kanbay, MustafaÖz Seminal vezikül kistleri doğumsal ya da edinsel olarak karşımıza çıkar ve ejekülatuar kanalların tıkanıklığına bağlı olduğuna inanılır (1). Seminal vezikül kistleri nadir olarak görülür ve genellikle asemptomatikdirler. Çalışmamızda, her iki yan ağrısı ve prostatizm benzeri şikayetler nedeniyle kliniğimize başvurması sonucu konjenital seminal vezikül kisti saptanan 32 yaşında erkek olgu sunulmaktadırÖğe Konjenital seminal vezikül kisti(2013) Kahraman, Ayşegül; Ediz, Caner; Cemal, Taşdemir; Kahraman, Bayram; Altıntaş, RamazanSeminal vezikül kistleri doğumsal ya da edinsel olarak karşımıza çıkar ve ejekülatuar kanalların tıkanıklığına bağlı olduğuna inanılır (1). Seminal vezikül kistleri nadir olarak görülür ve genellikle asemptomatikdirler. Çalışmamızda, her iki yan ağrısı ve prostatizm benzeri şikayetler nedeniyle kliniğimize başvurması sonucu konjenital seminal vezikül kisti saptanan 32 yaşında erkek olgu sunulmaktadırÖğe Renal rüptüre hemorajik anjiomyolipomlarda konservatif yaklaşım: Olgu sunumu(2013) Kanbay, Mustafa; Altıntaş, Ramazan; Kahraman, Ayşegül; Ediz, Caner; Taşdemir, Cemal; Kahraman, BayramAnjiomyolipom, değişen oranlarda düz kas, displastik kan damarları ve yağ dokusundan oluşan en sık görülen benign mezenkimal böbrek tümörüdür. 4 cm’den küçük lezyonlar çoğunlukla bulgu vermez. 4 cm’den büyük lezyonlarda kanama riski artar ve lezyon semptomatik hale gelebilir. Burada, sol yan ağrısı şikayeti ile başvuran, hemorajik anjiomyolipom saptanan 46 yaşında kadın olgu sunulmaktadır.Öğe An Unusual Cause of Extremity Weakness: Von Hippel-Lindau Disease and Advantages of Radiologic Imaging on Diagnosis(Turgut Özal Tıp Merkezi Dergisi, 2015) Görmeli, Cemile Ayşe; Aydın, Zeynep Banu; Görmeli, Gökay; Aydın, Hasan; Dursun, Recep; Kahraman, Ayşegül; Özdemir, Zeynep; Durak, Mehmet AkifÖz: Von Hippel Lindau Hastalığı, 3. kromozomun kısa kolundaki hasar nedeniyle oluşan nadir görülen otozomal dominant bir hastalıktır. Von Hippel Lindau Hastalığı'nın prevelansı 1: 35000-1: 40000 olarak bildirilmiştir. Retinal hemanjiom ve merkezi sinir sistemi hemanjiomları hastalığın ana belirtileri olmakla beraber adrenal feokromasitoma, paraganglioma, böbrek hücre tümörleri, pankreatik kistler, nöroendokrin tümörler ve epididim kistleri daha sonra eşlik edebilir. Bu hastalık fenotipik değişkenlik gösteren multi sistemik bir hastalıktır. Elli yaşında erkek hasta, 2 aydır devam eden sağ üst ve alt ekstremitede güçsüzlük öyküsü ile başvurdu. Manyetik rezonans incelemelerinde serebellar ve spinal hemanjioblastomlar; pankreatik ve renal kistler saptandı. Bu olguda merkezi sinir sisteminde semptomatik hemanjiomları, çoklu renal ve pankreatik kistleri olan Von Hippel Lindau tanısı alan olgunun radyolojik görüntülerini ve klinik seyrini sunmayı amaçladık. Başlık (İngilizce): Ekstremite Güçsüzlüğünün Nadir Görülen Bir Sebebi: Von Hippel Lindau Hastalığı ve Radyolojik Görüntülemenin Tanıdaki Katkıları Öz (İngilizce): Von Hippel-Lindau disease is a rare autosomal dominant disease with the disorder matched with the short arm of chromosome 3. The prevalence of Von Hippel-Lindau disease has been estimated to be between 1: 35000-1: 40000. Retinal hemangioma and central nervous system (CNS) hemangioma are the main manifestations with later accompanying adrenal pheochromacytoma, paraganglioma, renal cell carcinoma, islet cell tumors, pancreatic cysts and neuroendocrine tumors, epididymal cysts, or cystadenoma and endolmphatic sac tumor of the inner ear. The disease is a multisystem disorder with phenotypic variability. A 50-year-old man presented with a 2-month history of weakness of the right upper and lower limbs. Magnetic resonance imaging revealed cerebellar and spinal hemangioblastomas. In this case report, we present the radiologic images and clinical features of apatient with von Hippel-Lindau disease along with symptomatic central nervous system hemangioblastomas and multiple renal and pancreatic cysts.Öğe The Validity and Reliability of the Turkish Pet Attitude Scale(2022) Çevik Akyıl, Rahşan; Citlik Saritas, Seyhan; Kahraman, Ayşegül; Akyıl, Musa Şamil; Abacıgil, FilizObjective: This study tests the Turkish validity and reliability of the Pet Attitude Scale (PAS) and adapt it to Turkish society. Materials and Methods: The study population consisted of students in the departments of health at a university in Western Turkey. No sampling method was used; and the entire population was included in the study. Data were collected using a questionnaire on the participants’ sociodemographic characteristics and the PAS, which consisted of 18 items scored between 1 and 7 under three factors: love and interaction, pets in the home, and joy of pet ownership. The construct validity of the scale was evaluated by Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA). The reliability of the PAS was assessed by Cronbach’s alpha internal consistency coefficient, the item-total correlation, and the test-retest analysis. Results: The scale factors’ Cronbach’s alpha reliability coefficient ranged between 0.45 and 0.92, the items’ factor loads ranged between 0.51 and 0.85, and the total item correlation coefficients ranged between 0.31 and 0.77. The CFA supported the three-factor structure yielded by the EFA and showed good fit indices. Conclusion: The scale was reliable for Turkish society compared to the original PAS. The factor structure resembled the results of a reevaluation of PAS. Thus, it can be suggested that the PAS is valid and reliable for application in Turkish society.
