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Öğe Assessment of myocardial changes in athletes with native T1 mapping and cardiac functional evaluation using 3 T MRI(The International Journal of Cardiovascular Imaging, 2016) Görmeli, Cemile Ayşe; Görmeli, Gökhan; Yağmur, Jülide; Özdemir, Zeynep Maraş; Kahraman, Ayşegül Sağır; Çolak, Cemil; Özdemir, RamazanAbstract Intensive physical exercise leads to increases in left ventricular muscle mass and wall thickness. Cardiac magnetic resonance imaging allows the assessment of functional and morphological changes in an athlete’s heart. In addition, a native T1 mapping technique has been suggested as a non-contrast method to detect myocardial fibrosis. The aim of this study was to show the correlation between athletes’ cardiac modifications and myocardial fibrosis with a native T1 mapping technique. A total of 41 healthy non-athletic control subjects and 46 athletes underwent CMR imaging. After the functional and morphological assessments, native T1 mapping was performed in all subjects using 3.0 T magnetic resonance imaging. Most of the CMR findings were significantly higher in athletes who had C5 years of sports activity when compared with non-athletic controls and athletes who had \5 years of sports activity. Significantly higher results were shown in native T1 values in athletes who had \5 years of sports activity, but there were no significant differences in the left ventricular end-diastolic volume, left ventricular end-diastolic mass, or interventricular septal wall thickness between non-athletic controls and athletes who had \5 years of sports activity. The native T1 mapping technique has the potential to discriminate myocardial fibrotic changes in athletes when compared to a normal myocardium. The T1 mapping method might be a feasible technique to evaluate athletes because it does not involve contrast, is non-invasive and allows for easy evaluation of myocardial remodeling.Öğe Cerebrospinal fluid dynamics in patients with multiple sclerosis: the role of phase-contrast mrı inthe differential diagnosis of active and chronic disease(Korean radıologıcal soc, 121-8 yangjae-dong, seocho-gu, seoul 137-130, south korea, 2018) Oner, Serkan; Kahraman, Ayşegül Sağır; Özcan, Cemal; Özdemir, Zeynep Maraş; Ünlü, Serkan; Kamisli, Özden; Oner, ZulalObjective: Multiple sclerosis (MS) is an inflammatory disease characterized by demyelinating plaques in the white matter. Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a new hypothesis for the etiopathogenesis of MS disease. MS-CCSVI includes a significant decrease of cerebrospinal fluid (CSF) flow through the cerebral aqueduct secondary to an impaired venous outflow from the central nervous system. This study aimed to determine whether CSF flow dynamics are affected in MS patients and the contributions to differential diagnosis in active and chronic disease using phase-contrast magnetic resonance imaging (PC-MRI). Materials and Methods: We studied 16 MS patients with chronic plaques (group 1), 16 MS patients with active plaques-enhanced on MRI (group 2), and 16 healthy controls (group 3). Quantitatively evaluation of the CSF flow was performed from the level of the cerebral aqueduct by PC-MRI. According to heart rates, 14-30 images were obtained in a cardiac cycle. Cardiac triggering was performed prospectively using finger plethysmography. Results: No statistically significant difference was found between the groups regarding average velocity, net forward volume and the average flow (p > 0.05). Compared with the controls, group 1 and group 2, showed a higher peak velocity (5.5 +/- 1.4, 4.9 +/- 1.0, and 4.3 +/- 1.3 cm/sec, respectively; p = 0.040), aqueductal area (5.0 +/- 1.3, 4.1 +/- 1.5, and 3.1 +/- 1.2 mm(2), respectively; p = 0.002), forward volume (0.039 +/- 0.016, 0.031 +/- 0.013, and 0.021 +/- 0.010 mL, respectively; p = 0.002) and reverse volume (0.027 +/- 0.016, 0.018 +/- 0.009, and 0.012 +/- 0.006 mL, respectively; p = 0.000). There were no statistical significance between the MS patients with chronic plaques and active plaques except for reverse volume. The MS patients with chronic plaques showed a significantly higher reverse volume (p = 0.000). Conclusion: This study indicated that CSF flow is affected in MS patients, contrary to the hypothesis that CCSVI-induced CSF flow decreases in MS patients. These findings may be explained by atrophy-dependent ventricular dilatation, which may occur at every stage of MS.Öğe Incidence and clinical presentation of portal vein thrombosis in cirrhotic patients(La radiologia medica, 2016) Görmeli, Cemile Ayşe; Özdemir, Zeynep Maraş; Kahraman, Ayşegül Sağır; Yağmur, Jülide; Özdemir, Ramazan; Çolak, CemilPurpose The aim of this study was to examine the correlation between ventricular function and the extracellular volume fraction (ECV) in patients with non-ischemic dilated cardiomyopathy (NIDCM) using 3.0 T magnetic resonance imaging (MRI). We also hypothesized that native T1 and ECV values would be increased in patients with NIDCM, independent of the left ventricular ejection fraction (LVEF). The findings of our study could lead to further studies of the follow-up protocols.Öğe Nöroendoskopik Üçüncü Ventrikülostomi Operasyonu Geçirmiş Olan Bir Hastanın Faz Kontrast- Manyetik Rezonans Görüntüleme ile BOS Akımının Değerlendirilmesi(Causapedia, 2017) Ünlü, Serkan; Doğan, Metin; Kahraman, Ayşegül Sağır; Yıldırım, İsmail OkanÖz: Nöroendoskopik üçüncü ventrikülostomi, hidrosefalitedavisinde başarı ile kullanılan, morbiditesi düşük,başarı oranı yüksek bir tekniktir. Üçüncü ventrikültavanına açılan şantın fonksiyonel olup olmamasıtedavinin etkinliğini için önemlidir. Faz kontrast manyetik rezonans (FK-MRG) tekniği, beyin omuriliksıvısı (BOS) akımı ve BOS akım yolu hakkında invazivişleme gerek duymadan bilgiler vermektedir. Biz bu olgusunumu ile nöroendoskopik üçüncü ventrikülostomioperasyonu uygulanmış hastanın ventrikülostomioperasyonunun fonksiyonel olup olmadığını anlamaküzere FK-MRG yöntemi ile yapılan değerlendirmeyi vebulgularını sunmayı amaçladıkÖğe Proksimal tibyofibular eklemden kaynaklanan peroneal sinir yerleşimli intranöral ganglion kisti: preoperatif tanıda manyetik rezonans görüntülemesinin katkıları(İnönü Üniversitesi Tıp Fakültesi Dergisi, 2014) Özdemir, Zeynep Maraş; Kahraman, Ayşegül Sağır; Karakaplan, Mustafa; Topgül, Haldun; Görmeli, Cemile Ayşe; Hamurcu, Meryem MervePeroneal intranöral ganglion kisti, genelde erişkin yaşta erkeklerde ortaya çıkar ve nörolojik bulgulara yol açabilir. Hastaların çoğunda peroneal sinirin geçtiği fibula boynu laterali komşuluğunda ele gelen şişlik ve ağrı şikayeti ile karşılaşılmaktadır. Tanıda elektromiyografi ve radyolojik görüntüleme yöntemleri kullanılmaktadır. Biz burada dizinin dış yan tarafında ağrılı şişlik ve düşük ayak klinik tablosu ile başvuran 14 yaşında kız hastada alt ekstremite paralizisinin nadir nedenlerinden biri olan peroneal sinir yerleşimli intranöral ganglion kisti olgusunu sunduk. Sinir fonksiyonlarının geri kazanılabilmesi için mümkün olan en kısa zamanda cerrahi müdahale yapılmalıdır. Manyetik rezonans görüntülemesi (MRG) bu lezyonun hızlı ve doğru tanısına katkı sağlamakta ve tedavi yaklaşımlarına ışık tutmaktadır.Öğe Radiation dose comparison between prospectively ECG-triggered and retrospectively ECG-gated techniques of coronary computed tomography angiography on 256-slice dual source CT scanner(Turgut Özal Tıp Merkezi Dergisi, 2016) Görmeli, Cemile Ayşe; Kahraman, Ayşegül Sağır; Özdemir, Zeynep Maraş; Yağmur, Jülide; Özdemir, Ramazan; Açıkgöz, Nusret; Çolak, CemilAbstract Introduction: Coronary artery disease is an important cause of morbidity and mortality which is a common cardiovascular disease and the clinical presentation of atherosclerosis. Coronary computed tomography angiography is increasingly being used instead of the invasive catheter angiography. We aimed to determine the effective radiation dose of retrospectively ECG gated and prospectively ECG triggered technique of coronary computed tomography angiography for the assessment of coronary artery diseases. Materials and Methods: Three hundred and twenty six patients who underwent coronary computed tomography angiography were evaluated by using a 256 slice dual source scanner. We have used 3 different techniques depended to the heart rate of patients and compared the effective radiation dose between the techniques in our study. Results: The mean heart rates was demonstrated as 96,1 beat/minute in 195 patients with technique I, 80,7 beat/minute in 103 patients with technique II and 57,1 beat/minute in 28 patients with technique III. Also, the mean effective doses were calculated as 1,15 mSv in technique I, 3,98 mSv in in technique II and 10 mSv technique III. Conclusion: Prospectively ECG-triggered coronary computed tomography angiography ensures low effective radiation dose compared with retrospectively ECG gated for assessment of coronary artery diseases. Depended to the heart rate of the patient, the appropriate technique should be determined to obtain low radiation dose and an optimal image quality. Keywords: Coronary CT Angiography; Radiation Dose; 256-Slice Dual Source CT Scanner.Öğe Radiological evaluation in living donor liver transplantation (LDLT): the effets of variations in segment 4 artery on the ratio of left lobe volume to total liver volume(Turgut Özal Tıp Merkezi Dergisi, 2016) Kahraman, Ayşegül Sağır; Özdemir, Zeynep Maraş; Kahraman, Bayram; Görmeli, Ayşe Cemile; Yılmaz, SezaiAbstract Aim: The aim of this study was to evaluate whether the variations in the origin of the segment 4 artery effects the left liver lobe volume ratio to the total liver volume in living donor liver transplantation (LDLT). Material and Methods: Multiphasic CT images were obtained in 136 potential donors (70 men, 66 women). The mean age was 32.6±9 years (ranging from 19 to 53). Volume-rendering techniques were used to evaluate hepatic arteries. The origins of the segment 4 arteries were noted. The volumes of the right lobe, the left lobe and the total liver were measured in each case. The ratios of the left lobe volume to the total liver volume were calculated and subjects were divided into two groups based on this ratio. There were 78 cases with this ratio of ≥ 30 % and 58 cases with this ratio of < 30% in Group1 and Group 2, respectively. Results: The origins of the segment 4 artery were left hepatic artery in 85 cases and variational in 51 cases. The significant difference was shown in right (p=0,003) and left lobe (p=0,000) volumes between two groups whereas not shown in total liver volumes (p=0,775). No significant difference was observed in origins of segment 4 arteries between two groups (p=0,82). Women significantly have greater ratios of left lobe volume than men (p=0,013). Conclusion: Our results indicate that the variations in the origin of the segment 4 arteries have no effects on the ratio of left lobe volume to total volume, and merits further study. Keywords: Living Donor Liver Transplantation; Volumetric Analysis; Hepatic Arterian Anatomy.Öğe Wandering intraperitoneal daughter vesicle following spontaneous rupture of a hydatid cyst: a case report(Turgut Özal Tıp Merkezi Dergisi, 2016) Kahraman, Ayşegül Sağır; Kahraman, Bayram; Çimen, Ayla; Özdemir, Zeynep Maraş; Görmeli, Ayşe CemileAbstract We aimed to present CT findings of spontaneously ruptured liver cyst hydatid with wandering intraabdominal daughter cyst. We present the case of a 39-year-old woman who presented with abdominal pain. An exophytic cystic mass in the liver was detected in the assessment of patient with sonography. On CT examination an unenhanced, exophytic, thin walled hypodens cystic mass (measured 8 cm) originating from segment III was diagnosed as cyst hydatid and follow-up recommended. Two weeks later, she was admitted to CT examination after experiencing acute abdominal pain. CT revealed that the liver cystic mass disappeared and another cystic mass with similar measurements with previous cyst occupying pelvis with minimal intraperitoneal free fluid. The diagnosis of ruptured cyst hydatid with wandering intraperitoneal doughter vesicle was made. Surgery confirmed our imaging findings. This unusual condition highlights the need for radiological follow-up of cyst hydatid as a potential cause of acute abdominal pain. Keywords: Computed Tomography; Liver; Hydatid Cyst; Rupture.Öğe Wandering intraperitoneal daughter vesicle following spontaneous rupture of a hydatid cyst: a case report(Turgut Özal Tıp Merkezi Dergisi, 2016) Kahraman, Ayşegül Sağır; Kahraman, Bayram; Çimen, Ayla; Özdemir, Zeynep Maraş; Görmeli, Ayşe CemileAbstract We aimed to present CT findings of spontaneously ruptured liver cyst hydatid with wandering intraabdominal daughter cyst. We present the case of a 39-year-old woman who presented with abdominal pain. An exophytic cystic mass in the liver was detected in the assessment of patient with sonography. On CT examination an unenhanced, exophytic, thin walled hypodens cystic mass (measured 8 cm) originating from segment III was diagnosed as cyst hydatid and follow-up recommended. Two weeks later, she was admitted to CT examination after experiencing acute abdominal pain. CT revealed that the liver cystic mass disappeared and another cystic mass with similar measurements with previous cyst occupying pelvis with minimal intraperitoneal free fluid. The diagnosis of ruptured cyst hydatid with wandering intraperitoneal doughter vesicle was made. Surgery confirmed our imaging findings. This unusual condition highlights the need for radiological follow-up of cyst hydatid as a potential cause of acute abdominal pain. Keywords: Computed Tomography; Liver; Hydatid Cyst; Rupture.
