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Öğe Anomalous Origin of the Left Coronary Artery from the Right Coronary Sinus(Medical Tribune Inc, 2012) Colak, Mehmet Cengiz; Erdil, Nevzat; Disli, Olcay; Kahraman, Ercan; Battaloglu, BektasAnomalous origin of the left coronary artery (LCA) from the right coronary artery sinus is a rare congenital coronary anomaly. We report a case of a 48-year-old symptomatic man who was admitted to our clinic with a history of hypertension, type 2 diabetes mellitus, myocardial infarction and hypercholesterolemia. Coronary angiography was performed revealing anomalous left coronary artery from the right coronary artery sinus. In addition, stenosis of RCA and well developed stenotic diagonal artery were detected with coronary angiography. We performed coronary by-pass with left internal mammarian artery to diagonal artery and vena saphena to right coronary artery (RCA). Both coronary angiography and intraoperative view should be evaluated well in patients with anomalous of the coronary artery.Öğe Anomalous origin of the left coronary artery from the right coronary sinus(Annals of Thoracic and Cardiovascular Surgery, 2012) Çolak, Mehmet Cengiz; Erdil, Nevzat; Dişli, Olcay Murat; Kahraman, Ercan; Battaloğlu, BektaşAnomalous origin of the left coronary artery (LCA) from the right coronary artery sinus is a rare congenital coronary anomaly. We report a case of a 48-year-old symptomatic man who was admitted to our clinic with a history of hypertension, type 2 diabetes mellitus, myocardial infarction and hypercholesterolemia. Coronary angiography was performed revealing anomalous left coronary artery from the right coronary artery sinus. In addition, stenosis of RCA and well developed stenotic diagonal artery were detected with coronary angiography. We performed coronary by-pass with left internal mammarian artery to diagonal artery and vena saphena to right coronary artery (RCA). Both coronary angiography and intraoperative view should be evaluated well in patients with anomalous of the coronary arteryÖğe Effects of rivaroxaban on myocardial ischemia-reperfusion injury in rats(2022) Kahraman, Ercan; Akça, Barış; Çolak, Mehmet Cengiz; Disli, Olcay Murat; Parlakpınar, Hakan; Battaloglu, Bektas; Erdil, NevzatMyocardial infarction and further ischemia-reperfusion injury is a life-threatening conditions in humans. In this study, the effects of rivaroxaban, an anticoagulant agent, were aimed to be studied in a myocardial ischemia-reperfusion (I/R) injury model in rats. Male Wistar-albino rats were allocated into three groups; Rivaroxaban (n=15), control (n=15) and sham (n=10). Myocardial ischemia (30 minutes) and then reperfusion (120 minutes) were surgically performed in the rivaroxaban given (3mg/kg/ day by gavage for 10 days before surgical procedures) and the control groups. Electrocardiography changes, blood pressure and heart rate were recorded before ischemia, and during the periods of ischemia and the reperfusion. Hemodynamic and blood parameters were recorded. Necrotic tissue in the myocardium was determined by the triphenyl tetrazolium chloride dye method. The extent of myocardial necrosis and risk area was calculated using a computer-assisted image program. In the rivaroxaban administered group, the size of necrotic area in the myocardium decreased significantly, however, mean heart rate and mean arterial blood pressure did not change. K+ and CK levels in serum, which are indicative of tissue necrosis, were significantly lower in the rivaroxaban group compared to the control group (p<0.05). Rivaroxaban use, compared to the control group, effectively reduced the extent of myocardial injury as assessed by less necrotic myocardial tissue in rats. This protective effect of rivaroxaban may be attributed to its less thrombus formation in the coronary arteries during ischemia and less acidosis during tissue damage.Öğe Hemodializ amaçlı arteriyovenöz fistül sonrası gelişen rüptüre dev anevrizma(2014) Yılmaz, Mehmet; Dişli, Olcay Murat; Kahraman, Ercan; Akça, Barış; Dönmez, Köksal; Çolak, Mehmet Cengiz; Erdil, Nevzat; Battaloğlu, BektaşÖz: Arteriyovenöz fistül (AVF) operasyonları, kronik böbrek yetmezliği olan olgularda hemodiyaliz uygulanmasını kolaylaştıran ve olgunun yaşam standartlarını yükseltmek amacıyla en sık kullanılan yöntemlerdir. Fistülün kullanılmasına bağlı geç dönemde en sık rastlanan komplikasyonlardan biri anevrizma gelişimidir. Bu çalışmada hemodiyaliz amaçlı açılan AVFnin, geç dönem komplikasyonu olarak ortaya çıkan rüptüre dev bir anevrizma olgusuna uyguladığımız cerrahi tedavi yaklaşımımız ve sonrasındaki klinik düzelmeyi özetlemeyi amaçladık.Öğe Myokardial iskemi-reperfüzyon hasarı üzerine rivaroksabanın etkileri(İnönü Üniversitesi, 2014) Kahraman, ErcanAmaç: İskemik dokunun kanlandırılmasından sonra ortaya çıkan reperfüzyon hasarının tedavisine yönelik bilimsel çalışmalar her geçen gün artmektadır. Son dönemde kullanıma giren oral faktör 10a inhibitörü olan rivaroksabanın iskemi reperfüzyon hasarı üzerine etkisi hyapılmış bir çalışma bulunmamaktadır. Giderek kullanım alanı genişleyen bu ilacın iskemi reperfüzyon hasarı üzerine olan etkilerinin bilinmesi ilacın klinik kullanımına ışık tutacaktır. Metot: Deneylerde Wistar-albino cinsi, 250-350 g ağırlığında erkek sıçanlar kullanıldı. Denekler Sham grubu (n=10), I/R grubu (n=15) ve Rivaroksaban uygulanan grup (n=15) olmak üzere üç gruba ayrıldı. Nekroz oluşturmak için sol koroner arterin inen dalına 30 dkiskemi-iki saat reperfüzyon uygulandı. EKG değişikleri, kan basıncı ve kalp hızı deneyboyunca kaydedildi. Nekrotik doku, Trifenil Tetrazolyum Klorid (TTC) boyası ile tayin edildi. Nekroz ve risk sahasının hacmiİmage Tool 2,0 program aracılığı ile hesaplandı. Bulgular: Rivaroksaban verilen grupta OKH ve OAKB'da belirgin bir değişiklik olmadan nekroz alanı azalmış olarak bulunmuştur. Ayrıca rivaroksaban uygulanan grupta doku nekrozunun göstergeleri olan K ve CK değerleri I/Rna göre istatistiksel olarak anlamlı oranda düşük bulundu. Sonuç: Bu sonuçlar, rivaroksabanın myokardial iskemi-reperfüzyon hasarında önemli bir rol oynadığını desteklemektedir. Rivaroksabanın myokardial doku hasarını iskemi sonrasında plazmda oluşan asidozu düzelterek yapmış olabilir. Asidozun düzelmesi renal tubuler düzeyde H+ atılımı üzerine rivaroksabanın etkilerine bağlı olabilir. Bu nedenle rivaroksabanın renal etkilerinin daha derinlemesine araştırılması ilacın I/R hasarı üzerine düzeltici etkilerinin açıklanmasına ışık tutabilir.Öğe Plevral kateter ile drenaj sırasında oluşan miyokardiyal yaralanmanın erken tanısı(İnönü Üniversitesi Sağlık Bilimleri Dergisi, 2017) Karaaslan, Erol; Kahraman, Ercan; Çolak, Mehmet CengizKardiyak ve kardiovasküler cerrahide tanı ve tedavi amaçlı kateter kullanımı ve kateter ile ilişkili komplikasyonlar halen vardır. Biz bu vakada pleurocan kateter ile drenaj sırasında oluşan myokardiyal yaralanmanın erken tanısı ve uygun tedavisini sunmayı amaçladık. Anahtar Kelimeler: Myokardiyal Yaralanma, Kateter, Tanı.Öğe Spontaneous Rupture of the Ascending Thoracic Aorta in Young Man(2015) Çolak, Mehmet Cengiz; Erdil, Nevzat; Kahraman, Ercan; Kutlu, Ramazan; Battaloğlu, BektaşAbstract: Spontaneous rupture of the aorta without previous history of trauma, hypertension or apparent aortic pathology is rare. Delayed or nonoperative repair of this condition is usually lethal. We report spontaneous rupture of the ascending thoracic aorta in young man. A 20-year-old male who had complained of sudden onset of severe chest pain and dispnea was admitted to our hospital. Initially, acute type A closing aortic dissection was suspected but computed tomography (CT) showed no intimal flap, false lumen or aortic aneurysm.Öğe Successful Mitral Valve Replacement in Patient with Severe Hemolytic Anemia Due to Tight Mitral Stenosis(2016) Akça, Barış; Seçici, Serkan; Kahraman, Ercan; Dişli, Olcay Murat; Çolak, Mehmet Cengiz; Battaloğlu, Bektaş; Erdil, NevzatA 43 year-old woman complained of palpitation and shortness of breath admitted to our hospital. Transthoracic echocardiography revealed severe mitral stenosis and moderate mitral regurgitation. In routine blood tests hemoglobin and lactate dehydrogenase levels were 7.6 g/dL, 520 IU/L respectively. Coombs test was negative. After studying the other intrinsic or extrinsic causes of hemolytic anemia patient's anemia was diagnosed as intravascular hemolytic anemia due to tight mitral stenosis. Therefore, mitral valve replacement planned and performed. Hemolysis was resolved after the mitral valve replacement. In conclusion, we report a case of hemolytic anemia due to mitral stenosis resolved by mechanical mitral valve replacement.Öğe Successful mitral valve replacement in patient with severe hemolytic anemia due to tight mitral stenosis(Med-Science, 2016) Akça, Barış; Seçici, Serkan; Kahraman, Ercan; Dişli, Olcay Murat; Battaloğlu, Bektaş; Erdil, NevzatA 43 year-old woman complained of palpitation and shortness of breath admitted to our hospital. Transthoracic echocardiography revealed severe mitral stenosis and moderate mitral regurgitation. In routine blood tests hemoglobin and lactate dehydrogenase levels were 7.6 g/dL, 520 IU/L respectively. Coombs test was negative. After studying the other intrinsic or extrinsic causes of hemolytic anemia patients anemia was diagnosed as intravascular hemolytic anemia due to tight mitral stenosis. Therefore, mitral valve replacement planned and performed. Hemolysis was resolved after the mitral valve replacement. In conclusion, we report a case of hemolyt ic anemia due to mitral stenosis resolved by mechanical mitral valve replacement.Öğe Successful mitral valve replacement in patient with severe hemolytic anemia due to tight mitral stenosis(Medicine Science, 2015) Akça, Barış; Seçici, Serkan; Kahraman, Ercan; Dişli, Olcay Murat; Çolak, Mehmet Cengiz; Battaloğlu, Bektaş; Erdil, NevzatA 43 year-old woman complained of palpitation and shortness of breath admitted to our hospital. Transthoracic echocardiography revealed severe mitral stenosis and moderate mitral regurgitation. In routine blood tests hemoglobin and lactate dehydrogenase levels were 7.6 g/dL, 520 IU/L respectively. Coombs test was negative. After studying the other intrinsic or extrinsic causes of hemolytic anemia patient’s anemia was diagnosed as intravascular hemolytic anemia due to tight mitral stenosis. Therefore, mitral valve replacement planned and performed. Hemolysis was resolved after the mitral valve replacement. In conclusion, we report a case of hemolytic anemia due to mitral stenosis resolved by mechanical mitral valve replacement.Öğe Thrombosis in pregnancy: Scientometric analysis of thrombotic diseases in pregnancy between 1975-2019(2020) Yildirim, Engin; Kahraman, ErcanAim : Thrombosis and embolism during pregnancy have bad obstetric results, and diagnosis and treatment are difficult. The number of publications published about thrombosis and embolism in pregnancy has been increasing gradually. Our aim is to make a comprehensive bibliometric analysis of the literature on thrombosis and embolism during pregnancy. Method and Methods: In this study, we downloaded the data of the publications from the Web of Science Core Collection. All items indexed in these databases between 1975 and 2019 were included. Documents produced in 2020 are excluded. While searching the database, the words 'pregnancy or pregnant', 'thrombosis or embolism' were used as keywords. Results: We found a total of 6885 documents between 1975-2019. The documents obtained were written in 18 different languages, 90.8% of them were produced in English, followed by German with 3.4% and French with 3.1%. The majority of the documents found were original articles. The USA has made tremendous progress in the study of thrombosis and embolism during pregnancy and is still an effective country. The most prolific writer Khamastra M.A. with 85 articles from England. and the most productive university was Mcmaster University, Canada. Conclusion: The issue of thrombosis and embolism should be considered as a widely published and cited study area in both obstetrics and cardiovascular system practice. Clinicians and researchers will be able to easily identify which articles are strong in cardiovascular system diseases and pregnancy, and in which subjects there are more citations.
