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    Diffusion-Weighted Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy Features of Abdominal Viscera in a Patient with Gaucher's Disease
    (Univ Sains Malaysia, Sch Medical Sciences, 2014) Kalayci, Tugce Ozlem; Erdem, Gulnur; Kutlu, Ramazan; Kahraman, Aysegul; Alkan, Alpay
    A 46-year-old woman with Gaucher's disease (GD) consulted our clinic for abdominopelvic magnetic resonance imaging (MRI), as physical examination had revealed hepatosplenomegaly. Upper abdominal MRI showed massive hepatosplenomegaly and innumerable hypointense splenic nodules on T1-weighted images. Diffusion-weighted MRI (DW-MRI) and magnetic resonance spectroscopy (MRS) were performed to liver parenchyma and splenic nodules. MRS revealed lactate, lipid, acetate, and alanine peaks in splenic nodules, and choline, creatine, lipid, myo-inositolglycine, and lactate peaks in the liver parenchyma. The DW-MRI showed diffusion restriction in splenic nodules. It was concluded that MRI is a reliable method for the diagnosis and follow up of GD. Coupling DW-MRI and MRS allows quantitative evaluation, thereby increasing the efficacy of the method. This is the first report in the literature presenting advanced abdominal MRI findings in GD.
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    Investigation of right lobe hepatic vein variations of donor using 64-detector computed tomography before living donor liver transplantation
    (Aves, 2014) Kalayci, Tugce Ozlem; Kutlu, Ramazan; Karasu, Sebnem; Yilmaz, Sezai
    Background/Aims: To investigate the anatomy and variations of right lobe accessory veins and segment 5-8 veins draining into middle hepatic vein with 64 slice multidetector computed tomography (CT). Materials and Methods: 100 consecutive living donor candidates underwent 64 slice CT angiography. Image interpretation was performed based on source axial images, multiplanar reformats, and three-dimensional post-processing images by the same radiologist. Results: Segment 5 and 8 veins with larger diameters were frequently found to be the proximal ones. Accessory hepatic veins were present in the great majority of cases (83%). Most of them were the inferior right hepatic veins (55%). All cases were classified according to the number of segment 5-8 veins and the presence or absence of a right accessory hepatic vein. Most of the donors had more than one segment 5-8 vein and right lobe accessory veins (57%). Conclusion: Multidetector CT is a valuable technique for investigating the venous anatomy of the liver in living donor candidates. Anatomy and variations of the hepatic veins can easily be evaluated by using multiplanar images.