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Öğe Congenital Aplasia of the External Ear Canal and Total Dehiscence of Mastoid-Tympanic Segment of the Facial Nerve as a Cause of Recurrent Facial Paralysis(Lippincott Williams & Wilkins, 2013) Toplu, Yuksel; Kalcioglu, Mahmut Tayyar; Karatas, Erkan; Bayindir, TubaFacial nerve (FN) macrodehiscence, in contrast to microdehiscence, generally occurs as a result of chronic otitis media and is rarely seen congenitally. A patient with normal hearing who had no history of ear disease or ear operation came to the clinic with recurrent facial paralysis (FP) and frequent blockage of the external ear canal with epithelial debris complaints. In the explorative ear surgery, we observed that the posterior wall of the external ear canal or tympanic ring was absent, a large external ear cavity was covered with a thin skin, the FN was under the skin, and the tympanic-mastoid segment of the FN and chorda tympani extending to the stylomastoid foramen was completely open. FP episodes were associated with the unprotected FN. To prevent an attack of FP, and to self-clean the external ears, mastoid obliteration surgery was performed, and the mastoid segment of the FN was covered with a conchal cartilage graft. This case was diagnosed as congenital aplasia of the external ear canal due to the tympanic bone aplasia-mastoid bone hypoplasia, and the dehiscence of the mastoid-tympanic segment of the FN, and as a cause of recurrent FP, has never to date been identified.Öğe Does cartilage thickness affect hearing results in real life? Long-term results of cartilage and fascia graft in type 1 tympanoplasty(Wiley, 2019) Kalcioglu, Mahmut Tayyar; Tuysuz, Ozan; Yalcin, Muhammed Zeki; Karatas, Erkan[Abstract Not Available]Öğe Evaluation of the Protective Effect of Beta Glucan on Amikacin Ototoxicity Using Distortion Product Otoacoustic Emission Measurements in Rats(Korean Soc Otorhinolaryngol, 2013) Bayindir, Tuba; Filiz, Aliye; Iraz, Mustafa; Kaya, Serdar; Tan, Mehmet; Kalcioglu, Mahmut TayyarObjectives. This experimental study investigated the possible protective effect of beta glucans on amikacin ototoxicity. Methods. Thirty-eight rats with normal distortion product otoacoustic emissions (DPOAEs) were divided into four groups. Group K was the control group. Group A was injected intramuscularly (i.m.) with amikacin 600 mg/kg/day between days 1-15. Group AB was given beta glucan gavage 1 mg/kg/day on days 0-15 and given amikacin 600 mg/kg/day i.m. on days 1-15. Group B was administered only beta glucan gavage, 1 mg/kg/day, on days 0-15.The DPOAEs were elicited in different frequency regions between 2,003 and 9,515 Hz, as distortion product diagrams (DPgrams), before and after the medication was administered, in all groups, on days 1, 5, 10, and 15. Results. No significant changes in the DPgrams were observed in group K. In group A, significant deterioration was observed at the 8,003 and 9,515 Hz frequencies on day 10, and at the 3,991, 4,557, 5,660, 6,726, 8,003, and 9,515 Hz frequencies on day 15. For group AB, statistically significant deterioration was observed at the 2,824, 8,003, and 9,515 Hz frequencies on day 15. The results for group B showed a significant improvement of hearing at the 2,378, 2,824, 3,363, and 3,991 Hz frequencies on day 1, at the 3,363, 3,991, and 8,003 Hz frequencies on day 10, and at the 8,003 Hz frequency on day 15. Conclusion. This study suggests that amikacin-induced hearing loss in rats may be limited to some extent by concomitant use of beta glucan.Öğe PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis) syndrome in children; surgical versus medical treatment?(2021) Toplu, Yuksel; Bayindir, Tuba; Tekin, Mehmet; Kalcioglu, Mahmut TayyarPFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical lymphadenopathy) syndrome usually presents in childhood and one of the most common periodic fever syndromes. The syndrome is self-limitted, characterized by periodic fevers at regular intervals and standard clinical features of pharyngitis, aphtous ulcers and cervical lympadenitis. The diagnosis is based upon clinical criteria with the exclusion of other recurrent fever causes. The treatment of PFAPA syndrome is divided two parts; to control of the acute attacks and to decrease the frequency of the attacks. In this retrospective study we aimed to compare the indications and efficiency of medical versus surgical treatment in children with PFAPA syndrome. Forty-five children with PFAPA syndrome whom treated with surgical or medical options were included and divided into two groups. The recovery rates before and after treatments were statistically analyzed. In both groups symptomatic improvement were seen. In surgical and medical treatment groups, complete clinical recovery was found 80% and 74%, respectively. Besides, statistically significant reduction in frequency (p<0.05) and duration (p<0.05) of recurrences in the incomplete clinical recovery cases were seen. Similar to literature our results support that both medical and surgical treatment are effective treatment methods. Surgery is a preferable treatment option especially in patients who do not response to medical treatment. The optimal strategy for management is depend on response to treatments.Öğe Prevalence of the Helicobacter pylori in the tonsils and adenoids(Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, 2015) Bayindir, Tuba; Toplu, Yuksel; Otlu, Baris; Yakupogullari, Yusuf; Yildirim, Ozge; Kalcioglu, Mahmut TayyarIntroduction: There is an ongoing debate about the existence and effects of Helicobacter pylori (Hp) in adenotonsillar tissue. Objective: A clinical study was conducted to assess the existence of Hp in the adenoid and/or adenotonsillar tissues, which were surgically excised due to chronic adenotonsillitis. Methods: Phosphoglucosamine mutase gene for the detection of Hp and cytotoxin-associated gene as virulence gene were examined in 84 adenotonsillar tissues obtained from 64 patients and patients' serum by using polymerase chain reaction. Results: Hp IgG was detected in 57 (89%) patients' serum. A total of seven tissue samples from 64 patients (10.9%) were found positive for Hp DNA, of which five were adenoids and two were tonsil tissues. All polymerase chain reaction positive samples were also positive for the cytotoxin-associated gene, which is a virulence determinant for the organism. Conclusion: This study suggests that children are exposed to Hp at an early age of their life in this province. Hp may have a role in the pathogenesis of chronic adenotonsillitis, especially in endemic areas. (C) 2015 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda. All rights reserved.Öğe Traumatic Thrombosis of Internal Carotid Artery Sustained by Transfer of Kinetic Energy(Lippincott Williams & Wilkins, 2012) Kalcioglu, Mahmut Tayyar; Celbis, Osman; Mizrak, Bulent; Firat, Yezdan; Selimoglu, ErolA 31-year-old male patient with a fatal thrombosis of the internal carotid artery caused by gun shot injury was presented in this case report. The patient was referred to the hospital with a diffuse edema on his left cheek. On otolaryngologic examination, there was a bullet entrance hole at the left mandibular corpus. No exit hole could be found. The finding from his axial computed tomography of neck and paranasal sinuses was normal. On neurological examination, a dense right hemiparesis was observed. In his cerebral angiogram, left common carotid artery was totally obliterated. Diffuse ischemia was observed in the left cerebral hemisphere. Despite intensive interventions, the patient died 4 days after the accident. In the autopsy, a large thrombosis was obtained in the left common carotid artery. This case emphasizes a fatal kinetic energy effect in vascular structures. It is stressed that a gun shot injury could be fatal with its indirect kinetic energy effects at subacute phase.
