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Öğe The effect of tramadole hcl and paracetamol on fracture healing in rat tibia model(2017) Ayranci, Baris; Kalender, Ali Murat; Sevimli, Reşit; Korkmaz, Mehmet Fatih; Bilal, ÖkkeşIn our research, we aim to study the effects of combined usage of tramadole HCl + paracetamol on rat tibia fracture model. In our study, 60 Wistar-Albino type male rats, weighted at 300-350 g., were divided as “control” and “test” ( tramadole HCl + paracetamol) groups Under general anesthesia, standard closed fractures were created on right tibias of all rats using blunt ended needle holder with three point principle and then closed reduction and fixing with intramedullary nail (0.7 mm) were provided. After fracture treatment of 30 rats in the test group, starting at the same day, 40mg/kg/day tramadole HCL was introduced as daily intermuscular dosage until they were sacrificed. Rats were sacrificed after the fractures as groups of 10 individuals at 2nd, 4th and 6th weeks. Healing fractured tibias were examined mechanically, radiologically, histopathologically. Results: No positive or negative radiological, biochemical and histological effect was detected after the long duration of tramadole HCL + paracetamol usage, starting from the first day and reaching to 6 weeks, in healing process of closed tibia fractures created and fixed with IM nails in rats. Considering the negative effects of NSAIDs on fracture healing, we think that tramadole HCl + paracetamol combination is a safe option in postoperative pain treatment after fractureÖğe İlimiz üst vericezaevi erkek tutuklularında kemik mineral yoğunluğu ölçümü(Türk Osteoporoz Dergisi, 2012) Bakan, Betül; Sucaklı, Mustafa Haki; Özer, Ali; Kalender, Ali Murat; Özkan, FuatÖz: Amaç: Kapalı cezaevinde kalan tutukluların kapalı ortamda ve sedanter yaşamaları sebebiyle osteoporoz gelişimi açısından artmış risk grubunda olup olmadıklarını araştırmak. Normal popülasyona göre düşük kemik mineral yoğunluğu (KMY) değerleri saptanması halinde koruyucu önlemler yönünden tutukluları ve sorumluları bilgilendirmek. Gereç ve Yöntemler: İlimiz E Tipi Kapalı Ceza İnfaz Kurumunda kalan 45 yaş üstü 66 erkek tutuklu ve kontrol grubu olarak cezaevinde kalmayan 45 yaş üstü 66 erkek gönüllü çalışmaya dahil edildi. Bütün katılımcıların yaş, meslek, cezaevinde kalma süresi, alışkanlıkları, beslenmeleri, egzersiz yapıp-yapmadıkları, hastalıkları ve kullandıkları ilaçlar sorgulanarak kaydedildi. KMY değerleri falangial radyografik absorbsiyometri (Alara MetriScan®) aleti ile ölçüldü. Bulgular: Çalışma grubunda falangial KMY 0,341±0,030 gr/cm2, kontrol grubunda 0,346±0,029 gr/cm2 olarak ölçülüp (p=0,968), çalışma grubunun falangial KMY değerleri kontrol grubundan daha düşük olarak bulundu. Sonuç: Kapalı cezaevinde kalan tutukluların falangial KMY değerleri kontrol grubundan daha düşük olup, cezaevinde kalma süresi ile falangial KMY değerleri arasında negatif korelasyon olduğu saptandı. Fakat grupların falangial KMY değerleri arasındaki fark istatistiksel olarak anlamlı bulunmadı.Öğe Measurement of Bone Mineral Density in Male Detainees(Galenos Yayincilik, 2012) Bakan, Betul; Sucakli, Mustafa Haki; Ozer, Ali; Kalender, Ali Murat; Ozkan, FuatAim: We aimed to investigate the increased risk for osteoporosis due to closed environment and sedentary lifestyle of prisoners. In his way, we planned to inform prisoners and supervisors for protective measures that should be taken if low bone mineral density (BMD) is detected compared with normal population. Materials and Methods: Sixty six prisoner men over the age of 45 as the study group and 66 male volunteers who are not detainees over the age of 45 as a control group were included in the study. All participants' age, occupation, duration in prison, habits, nutrition, exercise, diseases and medications used were noted. BMD values were measured using a phalangeal radiographic absorptiometry (Alara Metriscan(6)). Results: BMD values in the study group were measured as 0.341 +/- 0.030 g/cm(2) and as 0.346 +/- 029 g/cm(2) in the control group (p=0.968) BMD values of the study group were lower than those of the control group. Conclusion: In this study, we found that BMD values of the detainees were lower than those of the control group but this difference was not statistically significant. However, there was a negative correlation between BMD values and duration in prison.Öğe The Osteoporotic Effect of Arteriovenous Fistula on the lpsilateral Upper Extremity in Hemodialysis Patients(Galenos Yayincilik, 2013) Bakan, Betul; Kalender, Ali Murat; Ozer, Ali; Sucakli, Mustafa Haki; Ozkan, Fuat; Dogan, EkremObjective: Hemodialysis requires an arteriovenous fistula (AVF), the presence of which may influence the structure of nearby bone. This study analyzed the effect of AVF on ipsilateral upper extremity bone mineral density (BMD), as measured by phalangeal radiographic absorptiometry (RA). Materials and Methods: In this cross-sectional study, phalangeal BMD was measured in both arms by RA in a convenience sample of end-stage renal disease (ESRD) patients with a forearm AVF Patients were excluded if the patient had pathology which might affect distal arm circulation. BMD values (g/cm(2)) from forearms with AVF were compared with values from forearms without AVF Predialysis values of complete blood count, calcium, phosphorus, alkaline phosphatase, parathyroid hormone, urea, creatinine, potassium, albumin, total cholesterol, HDL cholesterol, and LDL cholesterol were determined in all patients; dialysis adequacy values were also calculated. Results: One hundred and sixteen patients agreed to participate in the study. Thirty-three patients were excluded, thus, data were analyzed from 83 patients (59% male, 41% female, mean hemodialysis time: 156 +/- 6 months, mean age: 53 +/- 16 years). AVFs were located in the nondominant hand in all patients. Phalangeal BMD in forearms with AVF (0.28 +/- 0.05 g/cm(2), range: 0.14-0.40) was significantly lower than that in the contralateral forearm (0.30 +/- 0.04 g/cm2, range: 0.79-0.40, p<0.05). Conclusion: In ESRD patients on hemodialysis, BMD is lower in the ipsilateral-to-AVF hand compared to the contralateral-to-AVF hand. In these patients, further investigations should be made to ascertain the ability of BMD assessment in determining fracture risk and to prompt physicians to initiate treatments which will preserve BMD and reduce fractures.Öğe The osteoporotic effect of arteriovenous fistula on the ıpsilateral upper extremity in hemodialysis patients(2013) Kalender, Ali Murat; Sucaklı, Mustafa Haki; Bakan, Betül; Özkan, Fuat; Doğan, EkremAmaç: Hemodiyaliz hastalarındaki arterio-venöz fistül (AVF), çevresindeki kemik dokunun yapısını etkileyebilir. Bu çalışmada falangial radyografik absorbsiyometri (RA) ölçümü ile AVFnin ipsilateral üst ekstremite kemik mineral yoğunluğu (KMY) üzerine etkisi araştırılacaktır. Gereç ve Yöntem: Bu kesitsel çalışmada, ön kollarında AVF olan son dönem böbrek yetmezlikli hastaların (SDBY) falangial KMY değerleri her iki koldan RA ile ölçüldü. Distal kol dolaşımını etkileyebilecek herhangi bir patolojisi olan hastalar çalışma dışı bırakıldı. Fistüllü kol falangial KMY değerlericm2) fistülsüz kol falangial KMY değerleri (g/cm2) ile karşılaştırıldı. Tüm hastalara diyaliz öncesi tam kan sayımı yapıldı, kalsiyum, fosfor, alkalen fosfataz, paratiroid hormon, üre, kreatinin, potasyum, albümin, total kolesterol, HDL kolesterol ve LDL kolesterol değerleri ölçüldü; diyaliz yeterliliği değerleri hesaplandı. Bulgular: Çalışmaya 116 hasta katıldı. Otuz üç hasta çalışma dışı bırakıldı, 83 hastanın sonuçları değerlendirildi. Hastaların %59u erkek, %41i kadın olup, hemodiyalize girme süreleri 156± 6 ay ve yaşları 53±16 yıldı. AVF tüm hastalarda nondominant koldaydı. Fistüllü kolun falangial KMY değerleri (0,28±0,05 gr/cm2, aralık 0,14-0,40), kontralateral kola oranla anlamlı derecede düşüktü (0,30±0,04 gr/cm 2, aralık 0,19-0,40, p<0,05). Sonuç: SDBYli hemodiyaliz hastalarında fistüllü kol falangial KMY değerleri, fistülsüz kol falangial KMY değerlerine göre daha düşük bulundu. Bu hastalarda, kırık riskinin belirlenmesinde KMY ölçümünün rolünükoruyucu tedavinin gerekliliğini tespit etmek için daha ileri çalışmalara ihtiyaç vardır. Türk Fiz T p Rehab Derg 2012;59:236-41.Öğe Percutaneous surgery using Admix NoKorTM Non-Coring 16 G needle in cases with trigger finger(2017) Sevimli, Reşit; Korkmaz, Mehmet Fatih; Kurt, İbrahim; Kalender, Ali MuratIn this study mid- and long-term outcomes of the cases with trigger finger we treated using Admix NoKorTM have been presented. Percutaneous release procedures were applied for 24 fingers of 22 patients between May 2009 and May 2011. Preoperatively US was performed so as to confirm the presence of trigger finger. Diameters of the tendons of the affected and intact hands measured using US, were compared so as to be able to demonstrate thickening of the tendon of the trigger finger. The patients were monitored for an average period of 25.2 months. During surgery, clinically loss of the catching sensation was observed. In two patients percutaneous trigger finger release failed, so we have to proceed with open surgery. During open surgery, we observed longitudinal wounds on the tendon. One patient developed unilateral radial digital nerve damage. Percutaneous release of the trigger finger using Admix NoKorTM 16-G gauge needle can be preferred in the treatment of trigger finger. Trigger finger of the first digit requires more attentive approach and one should be aware of the complications. If required open surgery can be preferred
