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One of the rare causes of recurrent otitis media: Bruton’s disease
(2021) Kaplan, Bilge Kurmaz; Kaplan, Fatih
Bruton’s disease is an X-linked immunodeficiency. Recurrent bacterial infections are seen in patients with this disease. A 2-year-old male patient was brought to the otolaryngology clinic due to pain in both ears and tenderness. It was learned from his anamnesis that he had recurrent otitis media and pneumonia attacks previously. Lymphadenopathy was not palpable in head and neck examination. Tonsillar tissue was small in oropharyngeal examination. It was learned that the patient’s parents were cousins; there were no other features in his family history. The patient, who had a history of recurrent sinopulmonary infections and whose parents were related, was re- ferred to pediatric immunology clinic with a pre-diagnosis of immunodeficiency. The patient was diagnosed with Bruton’s disease. Regular intravenous immunoglobulin treatment every three weeks was started. No new infection was observed in the follow-up.