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    Comparison of histomorphological findings of cardinal ligament in patients with and without uterine prolapse
    (2020) Peker, Nurullah; Kirici, Pinar; Kaya, Sehmus; Yildirim, Ayhan; Karacor, Talip
    Aim: This study aimed to investigate histomorphological changes in cardinal ligaments between patients with and without uterine prolapse.Material and Methods: This study included 30 patients who underwent vaginal hysterectomy for POP-Q stage 4 uterine prolapse (Group 1) and 30 patients who underwent abdominal hysterectomy for benign reasons except uterine prolapse (Group 2) at a tertiary center hospital. Demographic data, parity, uterine weight, and histomorphological findings of cardinal ligaments were compared between the two groups.Results: Age and parity were significantly higher unlike uterine weight was lower in Group 1. In histomorphological findings of cardinal ligaments, vessel wall thickness, peripheral nerve thickness and the number of cells in the connective tissue stroma counted in 1 mm2 area were statistically significantly higher in Group 1. While the presence of extravasated erythrocytes was greater in Group 1, no significant difference was found between the two groups in terms of inflammation.Conclusion: It is obvious that some histomorphological changes are formed in the cardinal ligaments of patients with uterine prolapse due to pressure on the uterus. We believe that the increase in the number of extravasated erythrocytes and the thickness of the vascular wall and peripheral nerve should be supported by further studies.
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    Evaluation of specific heavy metal levels of pregnant women complicated by neural tube defects
    (2020) Karacor, Talip; Kirici, Pinar; Nacar, Mehmet Can; Bulbul, Mehmet; Onderci, Muhittin; Peker, Nurullah
    Aim: The etiology of neural tube defect (NTD) is still not clear enough. In our study, we aimed to evaluate plasma heavy metal levels of pregnant women with NTD and to determine whether there is a relationship between heavy metal levels and NTD severity.Material and Methods: TThis study was conducted in Adıyaman University, Department of Gynaecology and Obstetrics. The study included 38 pregnant women with NTD and 42 pregnant women with healthy infants. Pregnant women who have NTD were divided into two groups as NTD Type 1 and NTD Type 2 according to the anomaly type. Levels of heavy metals such as Mercury (Hg), Cadmium (Cd), Cobalt (Co), Lead (Pb), Manganese (Mn) and Arsenic (As) were compared between groups.Results: Plasma Hg, Co, Cd and Pb levels were higher in NTD group than control group. (p values, respectively; p 0.001, p = 0.001, p 0.001, p 0.001). As and Mn levels were not statistically different between the two groups (p values; p = .519, p = .819, respectively). In the NTD group, Hg was found to be higher in NTD Type 1 than NTD Type 2 (p 0.001).Conclusion: It is obvious that some histomorphological changes are formed in the cardinal ligaments of patients with uterine prolapse due to pressure on the uterus. We believe that the increase in the number of extravasated erythrocytes and the thickness of the vascular wall and peripheral nerve should be supported by further studies.
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    A rare cause of hypovolemic shock after cesarean delivery; Rectus sheath hematoma
    (2019) Bulbul, Mehmet; Karacor, Talip; Nacar, Mehmet Can; Simsek, Memet
    Rectus sheath hematoma (RSH) is usually a self-limiting uncommon condition seen under belly. It is very rare that the hematoma reaches the size of a surgical requirement and that it develops as a result of superior epigastric vessel injury. In this case, we presented treatment of RSH which caused hypovolemic shock due to superior epigastric vascular injury and treated with ligation of vessels with intraperitoneal sutures via Phannensteil incision. In conclusion, surgery should be considered in patients with a hematoma that is large enough to cause hemodynamic instability or hypovolemic shock. In these patients, treatment with good cosmetic results can be performed with the same incision with appropriate sutures without forming comorbidity in the patient.