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Öğe Analysis of urine biomarkers for early determination of acute kidney injury in non-septic and non-asphyxiated critically ill preterm neonates(Taylor & Francis Ltd, 2017) Elmas, A. T.; Karadag, A.; Tabel, Y.; Ozdemir, R.; Otlu, G.Objective: We designed the present study to test the hypothesis that urinary biomarkers might predict acute kidney injury (AKI) development in non-septic and non-asphyxiated critically ill preterm infants. We evaluated urine (u) sistatin-C (uCys-C), kidney injury molecule-1 (uKIM-1) and neutrophil gelatinase associate lipocaline (uNGAL) as markers of AKI. Methods: Sixty-four preterm infants with gestational age between 28 and 32 weeks were included in this study. Biomarkers were measured on day of life (DOL) 1, 3, and 7. Results: uNGAL levels in the AKI group were significantly higher than in no-AKI group on DOL 1, 3 and 7 (p = 0.016, p = 0.007 and p = 0.0014, respectively). Conclusions: uNGAL is sensitive, early, and noninvasive AKI biomarkers, increasing significantly in non-septic and non-asphyxiated critically ill preterm neonates.Öğe ASSESSMENT OF CURRENT APPROACHES OF SURFACTANT REPLACEMENT THERAPY IN NEONATAL INTENSIVE CARE UNITS AMONG TURKEY: NATIONAL SURVEY(Springer, 2016) Tunc, T.; Polat, A.; Acikel, C.; Karadag, A.; Bas, A. Y.; Erdeve, O.; Koc, E.[Abstract Not Available]Öğe Dexpanthenol Therapy Reduces Lung Damage in Hyperoxic Lung Injury in Neonatal Rats(Karger, 2015) Ozdemir, R.; Demirtas, G.; Parlakpinar, H.; Polat, A.; Tanbag, K.; Taslidere, E.; Karadag, A.[Abstract Not Available]Öğe Five complexes containing N,N-bis(2-hydroxyethyl)-ethylenediamine with tetracyanidopalladate(II): synthesis, crystal structures, thermal, magnetic, and catalytic properties(Taylor & Francis Ltd, 2013) Korkmaz, S. Aslan; Karadag, A.; Korkmaz, N.; Andac, O.; Gurbuz, N.; Ozdemir, I.; Topkaya, R.Five cyanide complexes, [Ni(N-bishydeten)Pd(CN)(4)] (1), [Cu(N-bishydeten)Pd(-CN)(2)(CN)(2)](n) (2), [Cu(N-bishydeten)(2)][Pd(CN)(4)] (3), [Zn(N-bishydeten)Pd(CN)(4)] (4), and [Cd(N-bishydeten)(2)][Pd(CN)(4)] (5) (N-bishydeten = N,N-bis(2-hydroxyethyl)-ethylenediamine), have been synthesized and characterized using various techniques. Different structures were formed when the M:L ratio was varied in copper complexes. The single-crystal X-ray diffraction analysis reveals that 2, a 1-D cyanide-bridged complex with 2,2-CT-type zigzag chain, was obtained by using 1:1M:L ratio whereas 3 was formed as a complex salt in a molar ratio of 1:2. The thermal stabilities determined from DTG(max) values of the first decomposition stages change in the order 1>5>4>3>2. Although an EPR signal was not observed for 1, the g parameters obtained from the EPR spectra of 2 and 3 indicate that Cu-II ions are located in tetragonally distorted octahedral sites (D-4h), and the ground state of the unpaired electron is (B-2(1g)). The magnetic behavior indicates a very small antiferromagnetic interaction below 10K for 1-3. In 3, there is a temperature-independent paramagnetism () due to the orbital moments of the d electrons. 1-3 were tested as catalysts in Suzuki and Heck coupling reactions.Öğe Human milk banking and milk kinship: perspectives of religious officers in a Muslim country(Springernature, 2015) Ozdemir, R.; Ak, M.; Karatas, M.; Ozer, A.; Dogan, D. G.; Karadag, A.OBJECTIVE: The present study aims to determine the knowledge, attitudes and views of the Muslim religious officers regarding infant feeding, breast milk, wet nursing, milk kinship and human milk banks (HMBs). STUDY DESIGN: A total of 401 religious officers were included in the study. Participants included 355 community service religious officers and 46 faculty religious officers. RESULTS: Two hundred fifty-four (63.3%) participants were in favor of administering donor human milk when breast milk is not available from the mothers. To the question 'What kind of human milk bank would you approve as far as the religious sensitivity is concerned?' a majority of the religious officers (71.3%) responded that they would only approve if the milk pool contained a restricted HMB where a limited number of recipients were allowed to use the mixtures in these milk pools. Only 7 (1.7%) participants advocated initiating Western-style HMBs in Turkey. CONCLUSION: Turkish religious officers have revealed that they would only approve the establishment of an alternative HMB by a maximum three donors where up to three recipients whose identities are known by one another are allowed to use donor milk from each milk pool.Öğe NEONATAL HEALTH SERVICES IN TURKEY(Medical & Surgical Research Journals Group, 2014) Karadag, A.; Dilmen, U.[Abstract Not Available]Öğe A NEW FINDING IN GLUTARIC ACIDEMIA TYPE II: DENTAL ANOMALIES(Medecine Et Hygiene, 2013) Simsek, N.; Bulut, E. T.; Yalcin, M.; Karadag, A.[Abstract Not Available]Öğe SIRENOMELIA ASSOCIATED WITH HYPOPLASTIC LEFT HEART IN A NEWBORN(Macedonian Acad Sciences Arts, 2017) Turgut, H.; Ozdemir, R.; Gokce, I. K.; Karakurt, C.; Karadag, A.Sirenomelia, also known as mermaid malformation/ syndrome, is a rare, serious congenital anomaly characterized by variable degrees of fusion of the lower limbs and associated with severe malformations of vertebral, genitourinary, cardiovascular system and single umbilical artery. The first pregnancy of a 25-year-old woman resulted in one twin born by Cesarian section at 32 weeks' gestation, who was referred to our hospital with cyanosis, a congenital anomaly and respiratory distress. On physical examination, there was no urogenital region and anal fissure and gender was indeterminate. The arms were in adduction and wrist in flexion position with four fingers on the right hand and two fingers on the left hand. There was a single lower extremity with a webbed single foot and two toes consistent with sirenomelia type IV radiologically. Abdominal ultrasonography showed urogenital system agenesis and echocardiography detected hypoplastic left heart. However, the patient died 4 hours after birth. The other twin was followed for 1 week for nutrition and respiratory support and was then discharged without any problems.