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Öğe Değişik Evrelerdeki Sirotik Karaciğer . Hastalıklarında Portal Vasküler Sistem Hemodinamisinin Doppler Ultras.Onografi İle Değerlendirilmesi(İnönü Üniversitesi, 2001) Karaman, İbrahimHaziran 1999 ile Nisan 2001 tarihleri arasında İnönü Üniversitesi Turgut Özal Tıp Merkezi Gastroenteroloji Ana Bilim Dalında sirotik karaciğer hastalığı tanısı ile takip edilen 45 hasta çalışmaya alındı. İncelemeden önceki son beş hafta içerisinde gastrointestinal kanaması olan, portal basıncı düşürmeye yönelik ya da portal hemodinamiyi değiştirdiği bilinen herhangi bir ilaç alan, PV ve SVTerinde trombüsü bulunan, grade 2 veya daha yüksek ensefalopatisi olan olgular çalışma dışında tutuldu. 16 kadın, 29 erkek toplam 45 hasta ve 12 kadın, 13 erkek toplam 25 sağlıklı bireyden oluşan kontrol grubu prospektif olarak çalışıldı. Hastalar modifiye Child-Pugh skorlamasma göre (Tablo 1) A (n: 11), B (n: 16) ve C (n: 18) evrelerine ayrıldı (3).Öğe Lower prevalence of non tumoral perfusion defects in left hepatic lobe during CT arterial portography with splenic artery injection(Eur J Radiol, 2004) Kutlu, Ramazan; Akbulut, Ahmet; Sığırcı, Ahmet; Alkan, Alpay; Karaman, İbrahim; Baysal, Tamer; Saraç, KayaObjective: To determine whether there is a difference in the prevalence of non-tumoral perfusion defects (NTPD) in left hepatic lobe during CT arterial portography (CTAP) through splenic (SA) and superior mesenteric artery (SMA) injection. Methods and patients: For the preoperative evaluation, 59 patients (20 females, 39 males) who either have colorectal carcinoma metastasis (n: 42) or hepatocellular carcinoma (n: 17) underwent CTAP examination. Patients were divided into two groups (SA and SMA) according to the injection artery. The presence and type of NTPD in the left hepatic lobe were determined and compared. Results: There were significant differences in peripherally located wedge shaped, perihilar-periligamentous and pericholecystic NTPD, but no significant difference was found in lobar/segmental defects between the groups. Conclusions: Our study demonstrated lower prevalence of NTPD in the left hepatic lobe in CTAPs performed through SA injection and we think that this could be explained by the streamlining of portal blood flow.Öğe Quantitative doppler evaluation of the splenoportal venous system in various stages of cirrhosis differences between right and left portal veins(J Clin Ultrasound, 2002) Kutlu, Ramazan; Karaman, İbrahim; Akbulut, Ahmet; Baysal, Tamer; Sığırcı, Ahmet; Alkan, Alpay; Aladağ, Murat; Seçkin, Yüksel; Saraç, KayaPurpose. The purpose of our study was to evaluate the relationship between the splenoportal hemodynamics in patients with cirrhosis and the stage of the disease. Methods. Patients with cirrhosis were grouped according to modified Child-Pugh scoring into stages A, B, and C of cirrhosis. A control group of healthy volunteers was included. After gastroenterologic clinical and laboratory examinations, all participants underwent a splenoportal Doppler sonographic evaluation in which the vessels’ diameter, area, and blood flow velocity were measured and blood flow rate and the congestion index in the splenoportal venous system were calculated. Results. Seventy-five patients with cirrhosis (25 women and 50 men) were enrolled; the control group consisted of 30 healthy volunteers (15 women and 15 men) with no liver disease. The mean age (± standard deviation) of the patients was 54.4 ± 14.8 years (range, 13–80 years) and of the control subjects was 47.3 ± 14.5 years (range, 18–72 years). No significant differences in vessel diameter, blood flow velocity, and blood flow rate were found in the main and left portal veins between the study group and the control group. In the right portal vein, we found decreases in the vessel diameter, blood flow velocity, and blood flow rate, and in the splenic vein, we found increases in vessel diameter and blood flow rate. The congestion index was increased in the main portal and splenic veins but was unchanged in the left portal vein. Conclusions. Although our data indicate that there is no difference in Doppler sonographic parameters of the main portal vein according to Child-Pugh scores, the hemodynamic differences between the left and right branches of the portal vein may be clinically useful in patients with cirrhosis.