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  • Küçük Resim
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    Clinical management of mastodynia in female patients under 35 years of age
    (2020) Karapolat, Banu
    Aim: Seen frequently in young women, mastodynia impairs patients’ quality of life by raising worries about breast cancer.Material and Methods: In this study, 101 mastodynia patients under 35 years of age who presented to our clinic between July 2018 and July 2019 were reviewed retrospectively. The data collected included age, family history of breast cancer, time passed since the onset of mastodynia, localization, relationship with menstrual cycles, physical examination findings, regularity of menstruation, breast USG results, number of outpatient clinic revisits, diagnoses made for those who were resistant to treatment upon a psychiatric examination, and general follow-up outcomes.Results: The ages of the patients ranged between 19 and 35 years. A family history of breast cancer was present in 10%. Mastodynia was cyclic in 70%. In breast USG, 58.4% of the patients had signs of BI-RADS 1. Those who had BI-RADS 2 and BI-RADS 3 were followed up for an average of 7 months and no malignancy developed. A psychiatric examination was administered to patients who were resistant to treatment and 23 (22.8%) were diagnosed with various psychiatric disorders, mostly with anxiety disorder and panic disorder. Specific treatments were given to these patients and mastodynia alleviated or disappeared in half of them.Conclusion: The incidence of breast cancer is very low in mastodynia patients under the age of 35 years. The main treatment approach for these patients should be to eliminate their worries about cancer and to relieve them mentally. A psychiatric examination can be useful in treatment-resistant cases.
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    The effects of rifampicin on wound healing
    (2020) Karapolat, Banu; Karapolat, Sami; Buran, Alaaddin; Kemal Okatan, Burcu
    Aim: The effects of topical antibiotics on the wound healing are one of the interesting aspects of medicine. The aim of this study is to investigate the effects of topically applied rifampicin on wound healing in skin defects.Material and Methods: Forty-two male adult Sprague Dawley rats were divided into two groups: Group A (n = 21) and Group B (n = 21). Circular full-thickness skin defects were formed in the right thoracoabdominal regions. Group A received once daily local saline and Group B received once daily rifampicin 1 cc topically applied on the wounds. The defect sizes were photographed at the baseline, and days 3, 7 and 10 and the reductions in wound sizes were measured. In each group, 7 rats were sacrificed on each of days 3, 7 and 10 and their defected region was resected. Specimens were histopathologically evaluated, and scored for inflammatory cells, collagen accumulation, granulation tissue, re-epithelialization, and features of skin defect such as what layers of the skin are affected by it, its size and whether it involves any abscess-necrosis. The results were statistically analyzed.Results: There was no statistically significant difference between groups in terms of healing rate. Comparison of scores for inflammatory cells and features of skin defect revealed statistically significant differences. Statistically significant results were obtained for collagen accumulation and granulation tissue formation in both groups. No statistically significant difference was found in re-epithelialization between the groups.Conclusion: Topically applied rifampicin in experimentally induced skin defects does not have a positive effect on wound healings.
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    Risk factors for axillary lymph node metastasis in breast cancer
    (2019) Kurnaz, Eray; Celebi, Bilgin; Karapolat, Banu; Kucuktulu, Uzer; Eken, Huseyin
    Aim: As well as in Turkey as in the rest of the World, breast cancer is an increasing health problem. Although the axillary lymph node dissection is seen as an integral part in the breast cancer treatment, for it provides staging and local control, it also leads to complications and morbidity.