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Öğe Acute amiodarone toxicity causing respiratory failure(Assoc Medica Brasileira, 2017) Kaya, Saltuk Bugra; Deger, Seyda; Hacievliyagil, Suleyman Savas; Aytemur, Zeynep AyferA 66-year-old male patient was referred to our clinic with severe pneumonia. Bronchoscopy was performed due to clinical worsening despite antibiotics and diuretic therapy, respiratory failure and radiographic progression. Because bacterial cultures of the bronchoalveolar lavage fluid were negative and after using amiodarone for almost one month, we eliminated amiodarone from his medication regimen due to suspicion of amiodarone toxicity. Accordingly, we also initiated systemic steroid therapy. Chest X-ray done after 72 hours showed a significant resolution of lung consolidations and the patient exhibited significant clinical improvement, with decline of his oxygen requirements.Öğe Assessment of clinical phenotypic characteristics of patients with angioedema without wheals in a turkish population(Ocean Side Publications Inc, 2024) Cakmak, Mehmet Erdem; Bostan, Ozge Can; Kaya, Saltuk Bugra; Karakaya, Gul; Kalyoncu, Ali Fuat; Damadoglu, EbruBackground: Angioedema (AE) is defined fi ned as localized, self-limited swelling of subcutaneous tissues and mucosa. Objective: The aim of this study was to compare the phenotypic characteristics of patients with AE without wheals. Methods: This prospective study included adult patients with recurrent AE without wheals. Demographic and laboratory data of the patients were recorded in the patient fi le when they presented to the outpatient clinic between August 2018 and August 2020. The patients were contacted by phone to evaluate whether their AE had gone into remission between October 2023 and January 2024. The phenotypic characteristics of AE subtypes were compared. Results: The study included a total of 143 patients. The average age, age of onset of AE, rates of diabetes mellitus, hypertension and coronary artery disease were higher in the patients with angiotensin-converting enzyme inhibitor (ACEI) use related acquired AE (AAE) (AAE-ACEI). The rates of allergic rhinitis, drug allergy, atopy, and aeroallergen sensitivity, and the median total immunoglobulin E level were higher in patients with idiopathic histaminergic AAE (AAE-IH). The rate of face and/or perioral AE attacks was higher in the patients with AAE-ACEI, AAE-IH, and idiopathic non-histaminergic AAE. The rate of AE attacks in limbs, abdominal, genital and other parts of the body was higher in patients with hereditary AE (HAE). The baseline AE activity score was lower in the patients with AAE-IH and higher in the patients with HAE. In longterm follow-up, the remission rate of AE attacks was significant fi cant higher in patients with AAE-ACEI and AAE-IH. Conclusion: The phenotypic characteristic features of Turkish patients with AE without wheals may vary, depending on the underlying AE pathogenesis. C1 inhibitor level and function, complement C4 and C1q, and genetic tests contributed to the diagnosis; other laboratory tests did not contribute to the diagnosis.Öğe A case report: Pulmonary involvement in rheumatoid arthritis(Inonu University Faculty of Medicine, Department of Chest Diseases, Malatya, Turkey, 2017) Kaya, Saltuk Bugra; Keles, Emir Omer; Otlu, Ceren; Hacievliyagil, Suleyman Savas; Aytemur, Zeynep Ayfer[Abstract Not Acailable]Öğe A Case Report: Pulmonary Involvement In Rheumatoid Arthritis(2017) Kaya, Saltuk Bugra; Keles, Emir Omer; Otlu, Ceren; Hacievliyagil, Suleyman Savas; Aytemur, Zeynep Ayfer57 years old male patient, due to the increase in 15 years follow-up of RA patients under cyclosporine therapy because of complaints by the rheumatology clinic patients considered as appropriate to launch abatement was directed to us by the patient isoniazid prophylaxis. A pleural effusion was diagnosed on chest X-ray. The patient was accompanied by thoracentesis on USG. The pleural effusions were exudative. Tracking of fever, cough, sputum complaint and low acute phase reactants excluded empyema. ADA levels were under 70, and TB pleurisy was excluded by the lack of growth in ARB and culture results. The lung involvement of RA was suspected without interstitial lung disease. Rheumatoid arthritis with interstitial lung disease is the commonest form of lung involvement; the incidence of pleural effusion and nodular lesions in the form is less common. Although pleural effusion has been reported before it was thought be caused by the new biological agents for treatment of rheumatoid arthritis.Öğe The effects of urban areas, neighborhood and housing on urban health: A systematic review and meta-analysis on asthma(Elsevier Sci Ltd, 2023) Kaya, Ahmet Burak; Camur, Kubra Cihangir; Cetin, Hasan Murat; Kaya, Saltuk Bugra; Erdoganaras, FatmaThe World Health Organization estimates that asthma will affect 5 % of the global population by 2025 when the number of patients will reach 400 million. In the past ten years, there has been a rise in the number of studies explaining the substantial development of illness in the 21st century (excluding hereditary causes) via urban structure components, and several pieces of evidence have been published on this subject. This study intends to perform a systematic review and meta-analysis to identify urban asthma risk factors. From April to November 2022, databases on PubMed, Scopus, and WoS were examined in this context. Only studies examining asthma and urbanization-related factors were included in the study. 127 articles were examined from 3276 studies obtained from databases. The analysis revealed that the pace of urbanization, air pollution, transportation network components, housing situation, and the locations of industrial regions were the most often highlighted risk factors. As conclusion; several urban factors were shown to have a substantial link with asthma. However, it was suggested that some of the urban risk variables used to define the urban area were insufficient and that the risk factors used to define the urban space should be varied or altered.Öğe Noninfectious causes of diffuse pulmonary infiltrations in chronic renal failure: metastatic pulmonary calsification(Via Medica, 2019) Kaya, Saltuk Bugra; Deger, Seyda; Hacievliyagil, Suleyman Savas; Aytemur, Zeynep AyferMetastatic pulmonary calsification (MPC) is a metabolic lung disease characterized by the deposition of calcium in pulmonary parenchyma. It may occur due to many bening or malign pathologies. Especially it is most commonly seen in patients with end stage chronic renal failure received renal replacement treatment. The case we report here involved a history of renal transplantation about 22 months ago. His thorax computed tomography had demonstrated bilateral disseminated infiltrations with ground-glass densities predominantly in the upper lobes and it was seen partially preserved subpleural areas and basal zones. The histopathological results in transbronchial lung biopsy indicated metastatic pulmonary calsification. We wanted to discuss patient with the accompaniment of literature.
