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    Evaluation of balance with video head impulse test and vestibulospinal tests in patients with substance use disorder
    (2022) Aydin, Ahmet; Kutluhan, Ahmet; Sahiner, Safak; Kaya, Sule
    Aim: The aim of this study was to investigate the long-term complications of substance use on the vestibular system. Substance use disorders are thought to impair the vestibular apparatus as well as the auditory system. Materials and Methods: Sixty-five cases with a history of non-alcohol drug addiction who survived the withdrawal phase and 22 healthy controls were included in the study. The cases were categorized into 2 different subgroups as those who had used only opioids ("opioid") and those who had used an opioid and chemical simultaneously or otherwise ("opioid &chemical"). Vestibulospinal tests and video Head Impulse Test (vHIT) were performed on all participants and the results were analyzed. Results: A total of 65 (61 males/4 females, mean age was 25 ± 3.95 years) cases and 22 (males, mean age was 25 ± 3.3 years) healthy controls were included in the study. The mean age of the "opioid" group (n=33) was 25 ± 3.95 years, and the mean age of the "opioid & chemical" group (n=32) was 25 ± 3.13 years (p>0.05). When the cases and controls were evaluated according to vestibulospinal tests, a high level statistically significant difference was observed (p<0.001), but no significant difference was found according to vHIT. Conclusion: This is the first study evaluating long-term vestibular functions with the vHIT test in patients with substance use disorder. Although the results suggest that there is no vestibulo-ocular reflex (VOR) involvement in the groups according to the vHIT, it has been revealed that substance use has negative effects on balance and walking.
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    Regional differences of Turkey in risk factors of newborn hearing loss
    (Elsevier Ireland Ltd, 2017) Konukseven, Ozlem; Kaya, Sule; Genc, Aydan; Muluk, Nuray Bayar; Basar, Figen Suren; Kirkim, Gunay; Tuncer, Ulku
    Objective: The aim of this study was to discover Turkish regional differences in the risk factors of newborn hearing loss. Method: A multi-centered retrospective design was used. A total of 443 children, registered to the national newborn hearing screening programme, with bilateral hearing loss, from five different regions of Turkey, were evaluated in terms of the types of hearing loss, the degree of hearing loss, the types of risk factors, parental consanguinity, age at diagnosis and age of auditory intervention, respectively. Results: There was no significant difference in the prevalence of hearing loss between regions (chi(2) = 3.210, P = 0.523). Symmetric Sensorineural Hearing Loss (SSHL) was the most common type of HL in all regions (91.8%). Profound HL was the most common degree of HL in all regions (46.2%). There were statistically significant differences between regions in terms of types of HL (chi(2) = 14.151, P = 0.000). As a total, 323 (72.9%) of subjects did not have any risk factors. There were statistically significant differences between regions in terms of the types of risk factors (pre, pen and post-natal) for SSNHL (chi(2) = 16.095, P = 0.000). For all regions, the age of diagnosis was convenient with the JCIH criteria. However the age of hearing aid application was prolonged in some regions. There were statistically significant differences between regions in terms of the age of diagnosis (chi(2) = 93.570, P = 0.000) and the age of auditory intervention (chi(2) = 47.323, P = 0.000). The confounding effects of gender, age of diagnosis, age of hearing aids applications, HL in the family, types of risk factors for HL on SSNHL were detected. Conclusion: To reach the goal of a high quality newborn hearing screening, there is a need to develop an evidence-based standard for follow up guideline. In addition, risk factors should be re-evaluated according to regional differences and all regions should take their own precautions according to their evidence based data. (C) 2017 Elsevier B.V. All rights reserved.