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    The association of ABO and serum ferritin levels with telogen effluvium in women
    (2018) Kaya Islamoglu, Zeynep Gizem; Sari, Nihal
    Aim: Telogen effluvium(TE) in women is a common problem in dermatology and has multiple etiologic causes. Low iron stores can be a possible contributing factor in TE. Although etiopathogenesis is not fully understood, many studies show remarkable associations between various diseases and ABO blood groups. Genomewide association studies have reported alleles in the ABO locus to be associated with ferritin levels. We had done this study with TE patients to detect serum ferritin levels and to find this relation between blood groups. Material and Methods: Healthy people and patients with TE were included in this study. A total of 103 females who have telogen effluvium and 125 controls were included. Results: ABO blood group and Rhesus factor distribution in patients with TE and distribution of healthy donors were similar. There haven’t any significant association between ferritin levels and blood groups in TE patients. Conclusion: There are many different causes in TE etiology, for this reason in our opinion, ferritin levels and other laboratory tests must be done. We conclude that there was no evocation between ABO blood groups, Rhesus factor and ferritin levels in TE, but this is the first study that can show this relationship and can be important for new studies which will be carried out in other centers with wider series.
  • Küçük Resim
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    Evaluation of frequency of irritable bowel syndrome in patients with chronic urticaria
    (2018) Kucuk, Adem; Unal, Mehmet; Kaya Islamoglu, Zeynep Gizem; Tuncez Akyurek, Fatma
    Aim: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder. Urticaria is a disease with papules and plaques accompanied by pruritus and edema. In this study, the relationship between these two diseases, which have many common features, was evaluated. Material and Methods: Patients with urticaria and volunteers who did not have any dermatologic disease were included in the study. Participants were assessed for diagnosis of IBS according to Rome III diagnostic criteria. In addition, findings supporting IBS diagnosis, and fecal shape and consistency were evaluated. Results: Fifty urticaria patients (18 males - 36% and 32 females - 64%) and 70 volunteers (38 males - 54.3% and 32 females - 45.7%) were evaluated. The mean age of the urticaria group was 34.8 ± 15.0; the mean age of the control group was 25.8 ± 10.9. IBS was detected in 34 (68%) patients in the urticaria group; and in 22 (31.4%) controls (p <0.001). Diagnosis-supporting findings were more frequently detected in the group of urticaria (p values respectively: 0.037; < 0.001; 0.036; 0.050). It was observed that the higher the serum IgE level, the higher the incidence of IBS in chronic urticaria patients ( p: 0.02; eta: 0.206). Conclusion: IBS was observed more frequently in urticaria patients. Diagnosis-supporting findings for IBS were found more frequently in urticaria patients. Serum IgE values also seem to be associated with IBS. These results indicate an association between chronic urticaria and IBS. For this reason, the presence of IBS in patients with chronic urticaria diagnosis should be questioned.