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  • Küçük Resim
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    The evaluation of chickenpox in the post-vaccination period in Turkey
    (2019) Bucak, Ibrahim Hakan; Almis, Habip; Kayak, Davut; Kilic, Fedli Emre; Geyik, Mehmet; Tekin, Mehmet; Konca, Capan; Turgut, Mehmet
    Keywords: key.br /Mateial and Methods: Patients aged 0-17 years presented to Adiyaman University Training and Research Hospital Pediatrics clinics and diagnosed with chickenpox between January 2013 and December 2016 were included in the study. Data were analyzed on Statistical Package for the Social Sciences (SPSS, version 22.0, Chicago, IL, USA) software. p0.05 was regarded as statistically significant.br /Results: 314 patients diagnosed with chickenpox were included in the study. Mean age of the subjects included was 84.76 ± 41.67 months, and 54.1% were males and 46.9% females. A significant difference was observed between the groups in terms of age (p=0.001). Cases’ ages decreased on a year-by-year basis. Fifty (15.9%) cases of chickenpox were identified as having been infected despite vaccine. A significant difference was determined between the mean ages of vaccinated and non-vaccinated patients with chickenpox.br /Conclusion: Although the addition of a single dose chickenpox vaccine to the national immunization schedule in Turkey reduces both severe complication and the incidence of the disease. In the light of our study we think that the addition of a second dose of chickenpox vaccination to our routine vaccine schedule will further reduce hospitalization numbers resulting from chickenpox-related complications. More comprehensive studies on the subject are now needed.br / Chickenpox, Child, Varicella, Vaccine.
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    Multidrug-resistant uropathogens in pediatric urinary tract ınfections: a multicenter retrospective trend analysis (2020-2024)
    (Springer, 2026) Erdogan, Esra; Yetisgen, Azize; Dogan, Serpil; Sinanoglu, Muhammed Selcuk; Kilic, Fedli Emre; Kurt, Osman
    Large-scale public health disruptions, including pandemics and natural disasters, may influence healthcare delivery, pathogen distribution, and antimicrobial resistance (AMR). This retrospective multicenter study evaluated uropathogen profiles and temporal trends in antibacterial resistance among hospitalized pediatric patients with urinary tract infections (UTIs) across periods corresponding to the COVID-19 pandemic, the February 6, 2023 Kahramanmara & scedil; earthquakes, and the post-earthquake phase in heavily affected regions of T & uuml;rkiye. Hospitalized pediatric patients (0-18 years) with culture-confirmed UTIs admitted between January 2020 and December 2024 to three tertiary care hospitals were included. Pathogen identification and antibacterial susceptibility testing were performed using standard microbiological methods in accordance with EUCAST criteria. Uropathogen distribution and resistance patterns were compared across predefined study periods. A total of 1131 pediatric patients were analyzed, of whom 54.29% were female. Gram-negative bacteria predominated (89.57%), with Escherichia coli (59.86%) and Klebsiella spp. (18.92%) being the most frequently isolated pathogens. Across the study periods, E. coli demonstrated significant increases in resistance to ampicillin (63.26% to 81.90%), ceftriaxone (41.99% to 53.76%), ceftazidime (39.46% to 63.10%), and trimethoprim-sulfamethoxazole (32.27% to 40.34%) (all p < 0.01). Among Klebsiella spp., a significant temporal increase was observed only for imipenem resistance, which rose from 18.64% during the COVID-19 period to 37.50% during the earthquake period before declining to 13.21% in the post-earthquake period (p = 0.021). Multidrug-resistant (MDR) phenotypes were predominantly detected among Gram-negative organisms, with the highest proportions observed in Serratia spp., Citrobacter spp., Enterobacter spp., and Pseudomonas spp., while MDR prevalence in E. coli was comparatively lower. Temporal variations in antibacterial resistance were observed among pediatric UTI pathogens during periods of major public health disruption. These findings highlight the importance of sustained regional surveillance and context-aware empiric treatment strategies in settings exposed to systemic healthcare stressors.