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Öğe Effects of sample temperature and storage time on arterial blood gases values(Drunpp-Sarajevo, 2012) Aydogan, Mustafa Said; Yucel, Aytac; Erdogan, Mehmet Ali; Sanli, Mukadder; Konur, Huseyin; Ozgul, Ulku; Togal, TurkanBackground: Arterial blood gas analysis is vital during diagnosis and treatment monitorization of mechanically ventilated patients. Work overload delays blood gas analysis lead to false results. Therefore syringes and the blood samples is recommended to kept cool or cold environment. The aim of this study is to investigate the effect of refrigerator-cooled syringes on blood gas analysis. Methods: We prepared 12 heparinized polypropylene plastic syringes for blood gas analysis for each patients before the study. Syringes divided in tree group as kept at room temperature (Group Room, n=4), or stored in the refrigerator for 30 minutes (Group Refrigerator, n=4), or stored in the refrigerator for 30 minutes but blood samples stored at room temperature (Group Refrigerator and Room, n=4). 40 for each patient's blood samples on mechanical ventilation were analyzed immediately as reference value (T-0). Samples analyzed at 15, 30, 45 and 60 minutes. Results: Patients characteristics and mechanical ventilation parameters were similar in the three groups. In terms of impact of sample temperature and storage time on arterial blood gas analysis; pH, pCO(2), and pO(2) values were not differ significantly among the groups (Table 2, P>0.05). There was significant difference in 60 minutes SpO(2) value among the groups (Table 2, P<0.05). Conclusion: Storage of syringes at room temperature or cooling in refrigerator was not affect arterial blood gas analysis results immediately before obtaining of blood samples. Blood gas analysis with plastic syringes at room temperature can provide safe results up to 60 minutes.Öğe Evaluation of pleth variability index as a predictor of fluid responsiveness during orthotopic liver transplantation(Wiley, 2016) Konur, Huseyin; Kayhan, Gulay Erdogan; Toprak, Huseyin Ilksen; Bucak, Nizamettin; Aydogan, Mustafa Said; Yologlu, Saim; Durmus, MahmutFluid management is challenging and still remains controversial in orthotopic liver transplantation (OLT). The pleth variability index (PVI) has been shown to be a reliable predictor of fluid responsiveness of perioperative and critically ill patients; however, it has not been evaluated in OLT. This study was designed to examine whether the PVI can reliably predict fluid responsiveness in OLT and to compare PVI with other hemodynamic indexes that are measured using the PiCCO(2) monitoring system. Twenty-five patients were enrolled in this study. Each patient was monitored using the noninvasive Masimo and PiCCO(2) monitoring system. PVI was obtained with a Masimo pulse oximeter. Cardiac index was obtained using a transpulmonary thermodilution technique (CITPTD). Stroke volume variation (SVV), pulse pressure variation, and systemic vascular resistance index were measured using the PiCCO(2) system. Fluid loading (10 mL/kg colloid) was performed at two different phases during the operation, and fluid responsiveness was defined as an increase in CITPTD >= 15%. During the dissection phase and the anhepatic phase, respectively, 14 patients (56%) and 18 patients (75%) were classified as responders. There were no differences between the baseline values of the PVI of responders and nonresponders. Area under the curve for PVI was 0.56 (sensitivity 35%, specificity 90%, p = 0.58) at dissection phase, and was 0.55 (sensitivity 55%, specificity 66%, p = 0.58) at anhepatic phase. Of the parameters, a higher area under the curve value was found for SVV. We conclude that PVI was unable to predict fluid responsiveness with sufficient accuracy in patients undergoing OLT, but the SVV parameter was reliable. Copyright (C) 2016, Kaohsiung Medical University. Published by Elsevier Taiwan LLC.Öğe Preoperative Iron Deficiency Increases Transfusion Requirements and Fatigue in Orthotopic Liver Transplantation(Wiley-Blackwell, 2012) Aydogan, Mustafa Said; Erdogan, Mehmet Ali; Yucel, Aytac; Konur, Huseyin; Bentli, Recep; Toprak, Huseyin Ilksen; Durmus, Mahmut[Abstract Not Available]Öğe The Use of Noninvasive Mechanical Ventilation in Myasthenic Crisis(Galenos Yayincilik, 2012) Aydogan, M. Said; Erdogan, M. Ali; Yucel, Aytac; Ozgul, Ulku; Konur, Huseyin; Togal, Turkan; Durmus, MahmutMyasthenia gravis is an autoimmune disease of the nicotinic acetylcholin receptors at the postsynaptic membrane of the neuromuscular junction. Myasthenic crisis, defined as respiratory failure requiring mechanical ventilation is a common life-threatening complication that occur approximately 15% to 20% of patients with MG. Endotracheal intubation and invasive mechanical ventilation have a number of complications and a high mortality. On the other hand, noninvasive mechanical ventilation is being successfully used in many pulmonary and neuromuscular diseases. There are few reports about the use of noninvasive mechanical ventilation in myasthenic crisis. We present a case with myasthenic crisis who was treated with noninvasive mechanical ventilation.
