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  • Küçük Resim
    Öğe
    Comparison of preoperative myometrial invasion on MRI with intraoperative frozen section in predicting adverse prognostic factors and survival in endometrioid endometrial cancer
    (2019) Akar, Serra; Guler, Abdul Hamid; Gul, Ayhan; Harmankaya, Ismail; Koplay, Mustafa; Tataroglu, Sumeyye Nur; Celik, Cetin
    Aim: There are no studies that have evaluated the accuracy of the finding of myometrial invasion in each modality in predicting adverse prognostic factors and survival. We compared the association of myometrial invasion on MRI and frozen section with presence of adverse prognostic factors and decreased disease-specific survival (DSS) in endometrioid endometrial cance. Material and Methods: A total of 149 patients diagnosed and treated surgically for endometrioid endometrial cancer at a single institution between 2010 and 2017 were included in the study. Accuracies of radiological myometrial invasion and frozen section myometrial invasion in predicting the histopathological myometrial invasion, other adverse prognostic factors and DSS were compared. Results: Frozen section had an accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 89.2%, 100.0%, 84.7%, 72.8% and 100.0%, respectively in diagnosing histopathological deep (≥50%) myometrial invasion with a kappa value of 0.876 (p<0.001). MRI had an accuracy, sensitivity, specificity, PPV and NPV of 71.3%, 55.8%, 80.6%, 63.2%, 75.3%, respectively with a kappa value of 0.392 (p<0.001) in predicting deep myometrial invasion. The accuracy of the finding of deep myometrial invasion on frozen section was higher than the finding of deep myometrial invasion on MRI in predicting the presence of adverse prognostic factors. However, the specificities and NPV’s were higher than their respective sensitivity and PPV values overall for both modalitiesd. Conclusion: Although MRI is frequently used in the preoperative evaluation of patients with endometrial cancer, the finding of deep myometrial invasion on MRI was not as accurate as that of frozen section in predicting the presence of adverse prognostic factors and poor survival. However, both test modalities demonstrated high specificity and NPV. As such both tests may provide higher efficacy in identifying patients without advanced disease who may not require complete lymph node dissection.
  • Küçük Resim Yok
    Öğe
    Cortical and cerebellar atrophy, but no lesion in a patient with neuro-Behcet's disease
    (Springer Wien, 2013) Varoglu, Asuman Orhan; Aksoy, Asude; Kocaturk, Idris; Ertekin, Ayfer; Koplay, Mustafa; Odabas, Faruk Omer; Ozbek, Seda
    Neuro-Beh double dagger et's disease (NBD) is a rare clinical entity. There are no reports about cortical atrophy in NBD. We report a patient with NBD exhibiting only cortical and cerebellar atrophy without any lesions. A 38-year-old male was hospitalized due to gait disorder. He had experienced forgetfulness, irritability, sexual and behavioral dyscontrol, and incontinence for 5 years. Magnetic resonance imaging (MRI) showed cortical and cerebellar atrophy, but there were no lesions. In the differential diagnosis of NBD, physicians should take into account the presence of both brainstem and cerebellar and cortical atrophy even in the absence of typical lesions for NBD, particularly in the presence of cognitive dysfunctions.
  • Küçük Resim
    Öğe
    Idiopathic Infected Spermatic Cord Hydrocele: A Case Report
    (2013) Çiftci, İlhan; Karabağlı, Pınar; Koplay, Mustafa
    Abstract:Spermatik kord hidroseli testis ve epididimin üzerinde spermatic korddan ayrı şekilde lokalize kistik sıvı toplanmasıdır. Bu durum az görülen konjenital anomalilerdendir. Akkiz olarak ta ortaya çıkabilir. İnfantlarda kord hidroselinin enfekte olması oldukça nadirdir. İdiyopatik oluşması literatürde bildirilmemiştir. Biz çalışmamızda sebebi bilinmeyen ve antibiyotik tedavisine cevap vermeyen 2 yaşında enfekte spertatik kord hidroseli olguyu sunduk. Enfekte kord hidroseli nadir görülsede scrotal bölgedeki cerrahi lezyonlarında ayırıcı tanıda yer almasa bile akılda tutulmalıdır. Bu az görülen durum acil cerrahi müdahale gerektirebilir, bu açıdan dikkat edilmelidir.
  • Küçük Resim
    Öğe
    Sebebi bilinmeyen enfekte spermatik kord hidroseli: olgu sunumu
    (İnönü Üniversitesi Tıp Fakültesi Dergisi, 2013) Çiftçi, İlhan; Pınar Karabağlı; Koplay, Mustafa
    Spermatik kord hidroseli testis ve epididimin üzerinde spermatic korddan ayrı şekilde lokalize kistik sıvı toplanmasıdır. Bu durum az görülen konjenital anomalilerdendir. Akkiz olarak ta ortaya çıkabilir. İnfantlarda kord hidroselinin enfekte olması oldukça nadirdir. İdiyopatik oluşması literatürde bildirilmemiştir. Biz çalışmamızda sebebi bilinmeyen ve antibiyotik tedavisine cevap vermeyen 2 yaşında enfekte spertatik kord hidroseli olguyu sunduk. Enfekte kord hidroseli nadir görülsede scrotal bölgedeki cerrahi lezyonlarında ayırıcı tanıda yer almasa bile akılda tutulmalıdır. Bu az görülen durum acil cerrahi müdahale gerektirebilir, bu açıdan dikkat edilmelidir..