Yazar "Korkmaz M.E." seçeneğine göre listele

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  • Küçük Resim Yok
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    Anti-aldosterone therapy in congestive heart failure
    (1994) Kizilkaya N.; Korkmaz M.E.; Muderrisoglu H.
    Apart from the well-defined renal effects, recent studies have shown the direct effects of aldosterone on cardiovascular system. These studies have shown that besides renal receptors, there are also aldosterone receptors in the heart, great vessels and brain. Stimulation of these receptors in mice may cause myocardial fibrosis and vasoconstriction while anti-aldosterone therapy can inhibit these untoward effects. Such therapy probably can also reduce the total mortality in patients with congestive heart failure. More importantly, aldosterone antagonists display these beneficial effects both on high and low blood pressure levels. These observations imply that anti-aldosterone therapy is effective through multiple mechanisms in congestive heart failure.
  • Küçük Resim Yok
    Öğe
    Monte Carlo studies in accelerator-driven systems for transmutation of high-level nuclear waste
    (2007) Şarer B.; Korkmaz M.E.; Günay M.; Aydin A.
    A spallation neutron source was modeled using a high energy proton accelerator. The aim is to maximize the minor actinides and fission products transmutation rates, which is created from the operation of nuclear power reactors for the production of electricity. The transmutation system is composed of a natural lead target, beam window, subcritical core, reflector, and structural material. The neutrons are produced by the spallation reaction of protons from a high intensity linear accelerator in the spallation target, and the fission reaction in the core. It is used a hexagonal lattice for the waste and fuel assemblies. The system is driven by a 1 GeV, 10 mA proton beam incident on a natural lead cylindrical target. The protons were uniformly distributed across the beam. The core is a cylindrical assembly. The main vessel is surrounded by a reflector made of graphite. The axes of the proton beam and the target are concentric with the main vessel axis. The structural walls and the beam window are made of the same material, stainless steel, HT9. We investigated the following neutronics parameters: spallation neutron and proton yields, spatial and energy distribution of the spallation neutrons, and protons, heat deposition, and the production rates of hydrogen and helium, transmutation rate of minor actinides and fission products. In the calculations, the Monte Carlo code MCNPX, which is a combination of LAHET and MCNP, was used. To transport a wide variety of particles, The Los Alamos High Energy Transport Code (LAHET) was used.