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  • Küçük Resim Yok
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    Comparison of dialysate and plasma NTproBNP in prediction of clinical outcomes of diabetic and nondiabetic peritoneal dialysis patients
    (DUSTRI-VERLAG DR KARL FEISTLE, BAHNHOFSTRASSE 9 POSTFACH 49, D-82032 DEISENHOFEN-MUENCHEN, GERMANY, 2018) Koz, Süleyman; Şahin, İdris; Kayataş, Mansur; Koz, Sema Tülay
    Background: Plasma level of N-terminal pro-brain natriuretic peptide (P-NTproBNP) is a useful marker in prediction of mortality in peritoneal dialysis (PD) patients. However, the predictive value of spent dialysate counterpart (D-NTproBNP) of plasma NTproBNP on mortality and dropout is not known. Materials and methods: Simultaneous P-NTproBNP and D-NTproBNP assays were performed after an overnight dwell in 44 scheduled ambulatory PD patients. Patients were followed for similar to 47 months. Deceased patients or patients who were transferred to hemodialysis were regarded as dropouts. Results: 14 patients (31.8%) dropped out at similar to 4 years (9 deaths and 5 transfers to hemodialysis). Diabetics, males, and patients with higher membrane permeability had higher dropout rates. Patients with P-and D-NTproBNP higher than median values had higher mortality and dropout rates (Kaplan-Meier test, log-rank Test p < 0.05). Odds ratios of D-NTproBNP for death and dropouts were (3.807 (0.907-15.971), p = 0.068) and (2.87 (1.009-8.138) p = 0.048), respectively; odds ratios of P-NTproBNP for death and dropouts were (4.652 (0.914-23.693), p = 0.064) and (2.67 (0.924-7.716), p = 0.07), respectively; in ROC analysis for death, AUC for P-and D-NTproBNP were 0.762 (0.578-0.946, p = 0.016) and 0.765 (0.590-0.940, p = 0.015), respectively. Exclusion of diabetic patients from the analyses resulted in significant changes in the predictive value P-and D-NTproBNP. Although death and dropout rates were still higher in nondiabetic patients with higher NTproBNP levels, the differences between groups lost statistical significance. Conclusion: Both P-NTproBNP and D-NTproBNP are significant predictors of outcomes of interest. Predictive value of NTproBNP might be different in diabetics and non-diabetic CAPD patients.
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    A kidney transplant centers Initial experiences in eastern Turkey
    (Transplantation Proceedings, 2012) Pişkin, Turgut; Ünal, Bülent; Koz, Süleyman; Ulutaş, Oğuz; Yağmur, Jülide; Kayhan, Başak; Taşkapan, Hülya; Şahin, İdris; Baysal, Tamer
    Objectives. Kidney transplantation is the best treatment method associated with improved quality of life and better survival for patients with end-stage renal disease. We started performing kidney transplantations in November 2010. We have performed 19 kidney transplantations so far. Fourteen of these were from living donors and five from deceased donors. Here, we present our initial experiences with 14 kidney transplant recipients from living donor kidney transplantations. Materials and methods. All recipients and their donors underwent detailed clinical history and examination. Recipients and their donors were followed in the transplant clinic during hospitalization. Results. The male-to-female ratio was 11:3 in recipients. The mean age of recipients was 27.8 years (range 4 –58 years). The number of the related, emotionally related, and unrelated transplantations were 9, 3, 2, respectively. The mean warm ischemic time was 95.7 seconds (range 52–168 seconds). Urine output started immediately after vascular anastomosis in all. The mean time of discharge from hospital was postoperative day 8 (range 4 –18 days). The mean flow up was 125 days (range 18 –210 days). Graft survival was 100% in this period, but one patient died from sepsis after 56 days. No kidney was lost from rejection, technical causes, infection, or recurrent disease. Conclusion. If transplant centers are as equipped and experienced as ours, kidney transplant programs should be started immediately so that they can reduce the number of the patients in waiting list for kidney transplantation.
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    Systemic lupus erythematosus associated gastrointestinal system vasculopathy in a patient with lupus nephropathy
    (Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, 2011) Ulutaş, Özkan; Cömert, Melda; Taşkapan, Hülya; Baysal, Tamer; Gündüz, Ercan; Koz, Süleyman; Pişkin, Turgut
    Öz: Sistemik lupus eritematosus (SLE) hastalarında gastrointestinal sistem (GİS) semptomları sıktır. SLE' ye bağlı GİS vaskülopatisi daha önce literatürde az bildirilmiş nadir bir klinik durumdur fakat kortikosteroidler ve diğer immünosüpresiflerle doğru tedavinin verilmesi ve gereksiz cerrahi uygulamalardan kaçınılması açısından akılda tutulması gerekir. Burada SLE tanısıyla Nefroloji Bölümünde takip edilen ve akut batın semptomlarıyla başvuran 33 yaşındaki hastanın GİS vaskülopati tanısı konulduktan sonra yüksek doz kortikosteroid ve siklofosfamidle tedavisi anlatılmaktadır.